ES458153A1 - Process for preparing 4-substituted imidazole compounds - Google Patents

Process for preparing 4-substituted imidazole compounds

Info

Publication number
ES458153A1
ES458153A1 ES458153A ES458153A ES458153A1 ES 458153 A1 ES458153 A1 ES 458153A1 ES 458153 A ES458153 A ES 458153A ES 458153 A ES458153 A ES 458153A ES 458153 A1 ES458153 A1 ES 458153A1
Authority
ES
Spain
Prior art keywords
preparing
imidazole compounds
substituted imidazole
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458153A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,044 external-priority patent/US4119781A/en
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of ES458153A1 publication Critical patent/ES458153A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Abstract

The imidazole compounds of the general formula II represent valuable intermediates for preparing pharmacologically active compounds. They are obtained by reacting a compound of the formula I in an organic solvent under basic conditions with a compound of formula R<2>-H. The symbols used in the general formulae I and II are defined in Claim 1.
ES458153A 1977-02-22 1977-04-25 Process for preparing 4-substituted imidazole compounds Expired ES458153A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/771,044 US4119781A (en) 1975-10-29 1977-02-22 Process for preparing 4-substituted imidazole compounds

Publications (1)

Publication Number Publication Date
ES458153A1 true ES458153A1 (en) 1978-04-01

Family

ID=25090518

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458153A Expired ES458153A1 (en) 1977-02-22 1977-04-25 Process for preparing 4-substituted imidazole compounds

Country Status (22)

Country Link
AR (1) AR217073A1 (en)
AT (1) AT355015B (en)
BE (1) BE853954R (en)
CA (1) CA1084052A (en)
CH (2) CH631167A5 (en)
DE (1) DE2718715A1 (en)
DK (1) DK168277A (en)
ES (1) ES458153A1 (en)
FI (1) FI73208C (en)
FR (1) FR2381031A2 (en)
GB (1) GB1582865A (en)
HU (1) HU174840B (en)
IE (1) IE45035B1 (en)
IL (1) IL51898A (en)
IN (1) IN148285B (en)
IT (1) IT1078449B (en)
LU (1) LU77200A1 (en)
MX (1) MX4663E (en)
NL (1) NL7704617A (en)
NO (1) NO152903C (en)
PT (1) PT66446B (en)
SE (2) SE442199B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AR217073A1 (en) 1980-02-29
AT355015B (en) 1980-02-11
FI73208B (en) 1987-05-29
IN148285B (en) 1981-01-03
SE8008935L (en) 1980-12-18
IT1078449B (en) 1985-05-08
FI771291A (en) 1978-08-23
SE442199B (en) 1985-12-09
IL51898A0 (en) 1977-06-30
IE45035L (en) 1978-08-22
SE452887B (en) 1987-12-21
DE2718715A1 (en) 1978-08-31
FR2381031A2 (en) 1978-09-15
NL7704617A (en) 1978-08-24
LU77200A1 (en) 1977-08-17
NO152903B (en) 1985-09-02
ATA289577A (en) 1979-07-15
DK168277A (en) 1978-08-23
IE45035B1 (en) 1982-06-02
BE853954R (en) 1977-10-26
CA1084052A (en) 1980-08-19
NO152903C (en) 1985-12-11
MX4663E (en) 1982-07-21
PT66446B (en) 1978-09-22
PT66446A (en) 1977-05-01
FR2381031B2 (en) 1982-09-17
CH631167A5 (en) 1982-07-30
NO771453L (en) 1978-08-23
IL51898A (en) 1980-07-31
SE7704870L (en) 1978-08-23
GB1582865A (en) 1981-01-14
HU174840B (en) 1980-03-28
CH631168A5 (en) 1982-07-30
FI73208C (en) 1987-09-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201