ES455870A1 - Diarylacetamidopropanes processes for producing them and compositions containing them - Google Patents

Diarylacetamidopropanes processes for producing them and compositions containing them

Info

Publication number
ES455870A1
ES455870A1 ES455870A ES455870A ES455870A1 ES 455870 A1 ES455870 A1 ES 455870A1 ES 455870 A ES455870 A ES 455870A ES 455870 A ES455870 A ES 455870A ES 455870 A1 ES455870 A1 ES 455870A1
Authority
ES
Spain
Prior art keywords
amine
diarylacetamidopropanes
processes
producing
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455870A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of ES455870A1 publication Critical patent/ES455870A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of formula: < IMAGE > are prepared from a correspondingly substituted diphenylacetic acid, either by condensation with an amine R1NH-(CH2)3-NR2R3, R2 representing hydrogen or a benzyl group, in which case a debenzylation is then carried out, or by condensation with an amine R1NH-(CH2)3-Z, Z representing certain radicals which can be split off, followed by a reaction with an amine R3NH2. For the meaning of the various symbols, reference will be made to Claim 1. The compounds and their salts have antiarrhythmic properties they can be used in the treatment of tachycardias or of disorders of the rhythm caused by digitalis.
ES455870A 1976-02-13 1977-02-11 Diarylacetamidopropanes processes for producing them and compositions containing them Expired ES455870A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7603929A FR2340724A2 (en) 1976-02-13 1976-02-13 NEW SUBSTITUTE DIARYLACETAMIDES, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING

Publications (1)

Publication Number Publication Date
ES455870A1 true ES455870A1 (en) 1978-01-16

Family

ID=9169055

Family Applications (1)

Application Number Title Priority Date Filing Date
ES455870A Expired ES455870A1 (en) 1976-02-13 1977-02-11 Diarylacetamidopropanes processes for producing them and compositions containing them

Country Status (12)

Country Link
JP (1) JPS52105156A (en)
AU (1) AU2222277A (en)
BE (1) BE851372A (en)
CA (1) CA1093582A (en)
CH (1) CH620906A5 (en)
DE (1) DE2705639A1 (en)
ES (1) ES455870A1 (en)
FR (1) FR2340724A2 (en)
GB (1) GB1574046A (en)
IL (1) IL51425A0 (en)
NL (1) NL7701509A (en)
PT (1) PT66182B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236956A (en) * 1988-11-04 1993-08-17 Kabi Pharmacia Aktiebolag Compounds for the treatment of urinary incontinence
SE8804003D0 (en) * 1988-11-04 1988-11-04 Pharmacia Ab COMPOUNDS FOR THE TREATMENT OF URINARY INCONTINENCE
US5066680A (en) * 1989-02-14 1991-11-19 Fujisawa Pharmaceutical Co., Ltd. Novel substituted-acetamide compound and a process for the preparation thereof
US5192779A (en) * 1989-02-14 1993-03-09 Fujisawa Pharmaceutical Co., Ltd. Substituted-acetamide compound and a process for the preparation thereof

Also Published As

Publication number Publication date
GB1574046A (en) 1980-09-03
JPS52105156A (en) 1977-09-03
PT66182A (en) 1977-03-01
AU2222277A (en) 1978-08-17
FR2340724B2 (en) 1980-05-23
FR2340724A2 (en) 1977-09-09
BE851372A (en) 1977-08-11
CH620906A5 (en) 1980-12-31
IL51425A0 (en) 1977-04-29
PT66182B (en) 1978-07-11
NL7701509A (en) 1977-08-16
DE2705639A1 (en) 1977-08-18
CA1093582A (en) 1981-01-13

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