SU604494A3 - Method of preparing 2,5-dimethyl-thieno-(3,2-f) morphane - Google Patents

Method of preparing 2,5-dimethyl-thieno-(3,2-f) morphane

Info

Publication number
SU604494A3
SU604494A3 SU762396747A SU2396747A SU604494A3 SU 604494 A3 SU604494 A3 SU 604494A3 SU 762396747 A SU762396747 A SU 762396747A SU 2396747 A SU2396747 A SU 2396747A SU 604494 A3 SU604494 A3 SU 604494A3
Authority
SU
USSR - Soviet Union
Prior art keywords
dimethyl
morphane
thieno
preparing
formula
Prior art date
Application number
SU762396747A
Other languages
Russian (ru)
Inventor
Гранадос Харке Рикардо
Алварес Доминго Мерседес
Босч Картес Хуан
Каналс Кабиро Хорхе
Мартинес Ролдан Кристобал
Рабадан Пейнадо Фернандо
Original Assignee
Лабораториос Маде С.А., (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лабораториос Маде С.А., (Фирма) filed Critical Лабораториос Маде С.А., (Фирма)
Application granted granted Critical
Publication of SU604494A3 publication Critical patent/SU604494A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)

Description

(54) СПОСОБ ПОЛУЧЕНИЯ 2,5-ДИMETИЛ-TИEHO(3,2-f)MOPФAHA Вычислено. %: с 59,11; Н 7,44; N5.74; а 14,54. Формуле  зовр« вии I 1. Сооооб получени  2 димет л- тш о- (3,2-f) морфмш формулы СИз10 . А 27 II / отпи аюшийс  тем, что смесь 2-(2 тенил)|, димет л 1,2,3,6тетрагидропнридина формулы ,-20 S . 8 tHg м O-IQ (а) т   2- (2 те|аш)г 1,4-рцтт -1,2, твтрашдроп р й «формулыг  . vn« S ««2 И trp СГ W си.  агревакпг при темперв у ж 130-135 С в йр сут ств и каслоты. 2. Способ во в., отл чвмщнйс  n«i, что в качестве кислоты иаюльзуют (мнсто водородную кислоту.(54) METHOD FOR OBTAINING 2,5-DIMETHYL-TIEHO (3,2-f) MOPHAHA Calculated. %: from 59.11; H 7.44; N5.74; a 14.54. Formula C i v i 1. Soooob for 2 dimetr (3,2-f) morphm of formula Siz10. A 27 II / otpi yuyus with the fact that a mixture of 2- (2 tenyl) |, dimetl 1,2,3,6 tetrahydropyridine of the formula, -20 S. 8 tHg m O-IQ (a) t 2- (2 te | Ash) g 1,4-rctt -1,2, tv trashdrop p ry "formulas. vn "S" "2 And trp SG W si. agrevakpg with temper at y 130-135 С per day of stv and caslotte. 2. A method in a century., Except for n i i, that as an acid is used (a lot of hydrogen acid.

SU762396747A 1975-09-20 1976-09-15 Method of preparing 2,5-dimethyl-thieno-(3,2-f) morphane SU604494A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES441142A ES441142A1 (en) 1975-09-20 1975-09-20 2-(2-thenyl)-1,4-dimethylpyridinium halides

Publications (1)

Publication Number Publication Date
SU604494A3 true SU604494A3 (en) 1978-04-25

Family

ID=8470020

Family Applications (5)

Application Number Title Priority Date Filing Date
SU762396747A SU604494A3 (en) 1975-09-20 1976-09-15 Method of preparing 2,5-dimethyl-thieno-(3,2-f) morphane
SU772472890A SU637084A3 (en) 1975-09-20 1977-04-22 Method of obtaining 2-(2-thenyl)-1,4-dimethyl-1,2,3,6-tetra-hydropyridines
SU772473620A SU626699A3 (en) 1975-09-20 1977-04-22 Method of producing 2-(2-thienyl)-1,4-dimethylpyridin bromide
SU772474104A SU633481A3 (en) 1975-09-20 1977-04-22 Method of obtaining 2-thienyl-(4-methyl-2-pyridyl) ketone
SU772472888A SU625611A3 (en) 1975-09-20 1977-04-22 Method of producing 2-(2-thienyl)-4-methylpyridine

Family Applications After (4)

Application Number Title Priority Date Filing Date
SU772472890A SU637084A3 (en) 1975-09-20 1977-04-22 Method of obtaining 2-(2-thenyl)-1,4-dimethyl-1,2,3,6-tetra-hydropyridines
SU772473620A SU626699A3 (en) 1975-09-20 1977-04-22 Method of producing 2-(2-thienyl)-1,4-dimethylpyridin bromide
SU772474104A SU633481A3 (en) 1975-09-20 1977-04-22 Method of obtaining 2-thienyl-(4-methyl-2-pyridyl) ketone
SU772472888A SU625611A3 (en) 1975-09-20 1977-04-22 Method of producing 2-(2-thienyl)-4-methylpyridine

Country Status (16)

Country Link
JP (1) JPS5257193A (en)
AR (1) AR214297A1 (en)
AT (1) AT352299B (en)
AU (1) AU502649B2 (en)
BE (1) BE845756A (en)
CA (1) CA1066283A (en)
CH (1) CH615682A5 (en)
DE (1) DE2641320C3 (en)
ES (1) ES441142A1 (en)
FR (5) FR2324302A1 (en)
GB (1) GB1553614A (en)
NL (1) NL7610438A (en)
NZ (1) NZ181891A (en)
PT (1) PT65595B (en)
SE (2) SE7610336L (en)
SU (5) SU604494A3 (en)

Also Published As

Publication number Publication date
AU502649B2 (en) 1979-08-02
GB1553614A (en) 1979-09-26
AR214297A1 (en) 1979-05-31
DE2641320A1 (en) 1977-03-24
FR2339610A1 (en) 1977-08-26
SU637084A3 (en) 1978-12-05
FR2324302B1 (en) 1978-12-15
AT352299B (en) 1979-09-10
BE845756A (en) 1977-03-01
DE2641320B2 (en) 1979-08-02
FR2339611A1 (en) 1977-08-26
SE8000206L (en) 1980-01-10
ES441142A1 (en) 1977-07-01
AU1762376A (en) 1978-03-16
FR2339609A1 (en) 1977-08-26
NZ181891A (en) 1979-01-11
SU625611A3 (en) 1978-09-25
ATA657776A (en) 1979-02-15
CA1066283A (en) 1979-11-13
FR2339608A1 (en) 1977-08-26
FR2324302A1 (en) 1977-04-15
NL7610438A (en) 1977-03-22
SU633481A3 (en) 1978-11-15
SU626699A3 (en) 1978-09-30
PT65595A (en) 1976-10-01
PT65595B (en) 1978-03-28
DE2641320C3 (en) 1980-04-03
JPS5257193A (en) 1977-05-11
CH615682A5 (en) 1980-02-15
SE7610336L (en) 1977-03-21

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