ES455791A1 - Procedimiento para preparar derivados de tetrahidro-equino- candina b. - Google Patents
Procedimiento para preparar derivados de tetrahidro-equino- candina b.Info
- Publication number
- ES455791A1 ES455791A1 ES455791A ES455791A ES455791A1 ES 455791 A1 ES455791 A1 ES 455791A1 ES 455791 A ES455791 A ES 455791A ES 455791 A ES455791 A ES 455791A ES 455791 A1 ES455791 A1 ES 455791A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- carried out
- acid
- candina
- equino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical group [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 229940098779 methanesulfonic acid Drugs 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- KJIFKLIQANRMOU-UHFFFAOYSA-N oxidanium;4-methylbenzenesulfonate Chemical compound O.CC1=CC=C(S(O)(=O)=O)C=C1 KJIFKLIQANRMOU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003880 polar aprotic solvent Substances 0.000 abstract 1
- CSFSSKWGOYOSPM-UHFFFAOYSA-N tetrahydroechinocandin b Chemical class N1C(=O)C2CC(O)CN2C(=O)C(C(C)O)NC(=O)C(NC(=O)CCCCCCCCCCCCCCCCC)CC(O)C(O)NC(=O)C2C(O)C(C)CN2C(=O)C(C(C)O)NC(=O)C1C(O)C(O)C1=CC=C(O)C=C1 CSFSSKWGOYOSPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH170676 | 1976-02-12 | ||
| CH340376 | 1976-03-18 | ||
| CH1446876 | 1976-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES455791A1 true ES455791A1 (es) | 1978-11-01 |
Family
ID=27173191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES455791A Expired ES455791A1 (es) | 1976-02-12 | 1977-02-10 | Procedimiento para preparar derivados de tetrahidro-equino- candina b. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS52116496A (ref) |
| AU (1) | AU2222977A (ref) |
| DE (1) | DE2704030A1 (ref) |
| DK (1) | DK46577A (ref) |
| ES (1) | ES455791A1 (ref) |
| FI (1) | FI770377A7 (ref) |
| FR (1) | FR2340947A1 (ref) |
| IL (1) | IL51426A0 (ref) |
| NL (1) | NL7701295A (ref) |
| PT (1) | PT66186B (ref) |
| SE (1) | SE7701155L (ref) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2742435A1 (de) * | 1976-09-28 | 1978-04-06 | Sandoz Ag | Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung |
| FI801773A7 (fi) * | 1979-06-08 | 1981-01-01 | Lilly Co Eli | Antibiootti A-30912 tekijä H. |
| FR2476074A1 (fr) * | 1979-12-13 | 1981-08-21 | Lilly Co Eli | Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques |
| CA1170598A (en) * | 1979-12-13 | 1984-07-10 | Bernard J. Abbott | Process for the preparation of cyclic peptide nuclei |
| US4803261A (en) * | 1986-06-27 | 1989-02-07 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide |
| US5055479A (en) * | 1988-06-16 | 1991-10-08 | Sankyo Company, Limited | Method of treating cachexia |
| US6030944A (en) * | 1991-10-01 | 2000-02-29 | Merck & Co., Inc. | Cyclohexapeptidyl bisamine compounds |
| US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
| US5552521A (en) * | 1995-02-10 | 1996-09-03 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
| CN120484066A (zh) * | 2019-12-06 | 2025-08-15 | 福建盛迪医药有限公司 | 棘白菌素类似物及其制备方法 |
-
1977
- 1977-02-01 DE DE19772704030 patent/DE2704030A1/de active Pending
- 1977-02-03 FI FI770377A patent/FI770377A7/fi not_active Application Discontinuation
- 1977-02-03 DK DK46577A patent/DK46577A/da not_active Application Discontinuation
- 1977-02-03 SE SE7701155A patent/SE7701155L/xx unknown
- 1977-02-08 NL NL7701295A patent/NL7701295A/xx not_active Application Discontinuation
- 1977-02-10 ES ES455791A patent/ES455791A1/es not_active Expired
- 1977-02-10 FR FR7703706A patent/FR2340947A1/fr not_active Withdrawn
- 1977-02-10 JP JP1315077A patent/JPS52116496A/ja active Pending
- 1977-02-11 IL IL51426A patent/IL51426A0/xx unknown
- 1977-02-11 PT PT66186A patent/PT66186B/pt unknown
- 1977-02-11 AU AU22229/77A patent/AU2222977A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT66186B (fr) | 1978-10-13 |
| NL7701295A (nl) | 1977-08-16 |
| AU2222977A (en) | 1978-08-17 |
| DK46577A (da) | 1977-08-13 |
| DE2704030A1 (de) | 1977-08-18 |
| PT66186A (fr) | 1977-03-01 |
| FI770377A7 (ref) | 1977-08-13 |
| IL51426A0 (en) | 1977-04-29 |
| SE7701155L (sv) | 1977-08-13 |
| JPS52116496A (en) | 1977-09-29 |
| FR2340947A1 (fr) | 1977-09-09 |
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