ES451135A1 - Dithiolanes and dithianes - Google Patents
Dithiolanes and dithianesInfo
- Publication number
- ES451135A1 ES451135A1 ES451135A ES451135A ES451135A1 ES 451135 A1 ES451135 A1 ES 451135A1 ES 451135 A ES451135 A ES 451135A ES 451135 A ES451135 A ES 451135A ES 451135 A1 ES451135 A1 ES 451135A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- chain
- carbon atoms
- hydroxyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Novel sulphur-containing compounds which have coronary-dilating properties, of the formula < IMAGE > in which R represents a radical of the formula < IMAGE > or < IMAGE > R1, R2 and R3 represent hydrogen, halogen, lower alkyl, lower alkoxy, aryl-lower-alkoxy, aryloxy, phenyl, nitro, amino, lower alkylthio, trifluoromethyl, hydroxyl, cyano, di-lower alkylamino, lower alkanoylamino, carboxyl, lower alkoxycarbonyl, lower alkylsulphonyl, hydroxymethyl, lower alkanoyloxy, amido, lower alkanoyl, sulphamoyl, mono- or di-lower-alkyl-sulphamoyl, aminocarbonyloxy, mono- or di-lower-alkyl-aminocarbonyloxy, lower-alkyl-amino-lower-alkyl, or two adjacent radicals together represent methylenedioxy, ethylenedioxy or butadien-1,3-yl-1,4-ene, R4 represents hydrogen or lower alkyl, R5, R6 and R7 represent hydrogen, halogen, lower alkyl, lower alkoxy, hydroxyl or benzyloxy, or two adjacent radicals together represent methylenedioxy or ethylenedioxy, X represents a sulphur atom, SO or SO2, Y represents a straight-chain or branched, optionally hydroxyl-substituted aliphatic radical having 2-8 carbon atoms of which 2-4 carbon atoms are located in the chain, and Z represents a straight-chain or branched, optionally hydroxyl-substituted aliphatic radical having 1-8 carbon atoms of which 1-4 carbon atoms are located in the chain, m denotes the numbers 0 or 1 and n denotes the numbers 2 or 3, and acid addition salts thereof are described. These compounds are prepared by a suitable 2-substitution of compounds of the formula
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1803073A CH611614A5 (en) | 1973-12-21 | 1973-12-21 | Process for the preparation of heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES451135A1 true ES451135A1 (en) | 1977-08-16 |
Family
ID=4429892
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES433172A Expired ES433172A1 (en) | 1973-12-21 | 1974-12-20 | Dithiolanes and dithianes |
| ES451137A Expired ES451137A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
| ES451134A Expired ES451134A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
| ES451136A Expired ES451136A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
| ES451135A Expired ES451135A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES433172A Expired ES433172A1 (en) | 1973-12-21 | 1974-12-20 | Dithiolanes and dithianes |
| ES451137A Expired ES451137A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
| ES451134A Expired ES451134A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
| ES451136A Expired ES451136A1 (en) | 1973-12-21 | 1976-09-01 | Dithiolanes and dithianes |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS595594B2 (en) |
| AT (5) | AT344693B (en) |
| AU (1) | AU511714B2 (en) |
| BE (1) | BE823625A (en) |
| CA (4) | CA1057295A (en) |
| CH (3) | CH611614A5 (en) |
| DD (1) | DD116829A5 (en) |
| DE (2) | DE2460593C3 (en) |
| DK (1) | DK148323C (en) |
| ES (5) | ES433172A1 (en) |
| FI (1) | FI67216C (en) |
| FR (1) | FR2255064B1 (en) |
| GB (3) | GB1489087A (en) |
| HK (1) | HK43380A (en) |
| HU (1) | HU170429B (en) |
| IE (1) | IE40788B1 (en) |
| IL (3) | IL46146A (en) |
| LU (1) | LU71530A1 (en) |
| NL (1) | NL158496B (en) |
| NO (1) | NO142669C (en) |
| PH (3) | PH19393A (en) |
| SE (2) | SE415763B (en) |
| YU (1) | YU39311B (en) |
| ZA (1) | ZA747526B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2515173A1 (en) * | 1981-10-28 | 1983-04-29 | Delalande Sa | 3-Methoxy 4-alkoxy benzaldehyde(s) - useful as intermediates for antibacterials, esp. trimethoprim and tetroxoprim |
| JPS60142297U (en) * | 1984-02-29 | 1985-09-20 | 株式会社豊田自動織機製作所 | Rotating device for swiveling driver's seat in forklift |
| JPS62171328U (en) * | 1986-04-23 | 1987-10-30 | ||
| DE3642331A1 (en) * | 1986-12-11 | 1988-06-23 | Basf Ag | BASICLY SUBSTITUTED PHENYL ACETONITRILES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM |
| US5434179A (en) * | 1989-06-06 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Method for improving brain function using cholinesterase-inhibiting aminoketone compounds |
| US7132547B2 (en) * | 2001-12-28 | 2006-11-07 | Takeda Pharmaceutical Company Limited | Preventives/remedies for urinary disturbance |
| US20100137403A1 (en) * | 2008-07-10 | 2010-06-03 | Scott Malstrom | Method for enhancing cognition or inhibiting cognitive decline |
-
1973
- 1973-12-21 CH CH1803073A patent/CH611614A5/en not_active IP Right Cessation
-
1974
- 1974-07-19 PH PH20012A patent/PH19393A/en unknown
- 1974-11-25 ZA ZA00747526A patent/ZA747526B/en unknown
- 1974-11-28 IL IL46146A patent/IL46146A/en unknown
- 1974-12-05 FI FI3527/74A patent/FI67216C/en active
- 1974-12-09 IE IE2531/74A patent/IE40788B1/en unknown
- 1974-12-17 PH PH16639A patent/PH13326A/en unknown
- 1974-12-18 NL NL7416507.A patent/NL158496B/en not_active IP Right Cessation
- 1974-12-18 CA CA216,313A patent/CA1057295A/en not_active Expired
- 1974-12-18 YU YU3368/74A patent/YU39311B/en unknown
- 1974-12-19 SE SE7416086A patent/SE415763B/en not_active IP Right Cessation
- 1974-12-19 DD DD183214A patent/DD116829A5/xx unknown
- 1974-12-19 LU LU71530A patent/LU71530A1/xx unknown
- 1974-12-19 DK DK668174A patent/DK148323C/en not_active IP Right Cessation
- 1974-12-20 GB GB23144/77A patent/GB1489087A/en not_active Expired
- 1974-12-20 AT AT1022674A patent/AT344693B/en not_active IP Right Cessation
- 1974-12-20 DE DE2460593A patent/DE2460593C3/en not_active Expired
- 1974-12-20 BE BE151729A patent/BE823625A/en not_active IP Right Cessation
- 1974-12-20 ES ES433172A patent/ES433172A1/en not_active Expired
- 1974-12-20 GB GB55146/74A patent/GB1489086A/en not_active Expired
- 1974-12-20 NO NO744615A patent/NO142669C/en unknown
- 1974-12-20 HU HUHO1757A patent/HU170429B/hu unknown
- 1974-12-20 GB GB23143/77A patent/GB1489088A/en not_active Expired
- 1974-12-20 JP JP49145875A patent/JPS595594B2/en not_active Expired
- 1974-12-20 DE DE2463173A patent/DE2463173C2/de not_active Expired
- 1974-12-23 FR FR7442521A patent/FR2255064B1/fr not_active Expired
-
1976
- 1976-09-01 ES ES451137A patent/ES451137A1/en not_active Expired
- 1976-09-01 ES ES451134A patent/ES451134A1/en not_active Expired
- 1976-09-01 ES ES451136A patent/ES451136A1/en not_active Expired
- 1976-09-01 ES ES451135A patent/ES451135A1/en not_active Expired
-
1977
- 1977-07-19 PH PH20013A patent/PH13396A/en unknown
- 1977-08-29 IL IL52844A patent/IL52844A0/en unknown
- 1977-08-29 IL IL52843A patent/IL52843A0/en not_active IP Right Cessation
-
1978
- 1978-01-06 AU AU32242/78A patent/AU511714B2/en not_active Expired
- 1978-01-19 AT AT38978A patent/AT350053B/en not_active IP Right Cessation
- 1978-01-19 AT AT38778A patent/AT349012B/en not_active IP Right Cessation
- 1978-01-19 AT AT39178A patent/AT349014B/en not_active IP Right Cessation
- 1978-01-19 AT AT38878A patent/AT349013B/en not_active IP Right Cessation
- 1978-04-27 SE SE7804879A patent/SE434746B/en not_active IP Right Cessation
- 1978-06-15 CH CH654178A patent/CH620921A5/en not_active IP Right Cessation
- 1978-06-15 CH CH654078A patent/CH620920A5/en not_active IP Right Cessation
-
1979
- 1979-03-26 CA CA324,131A patent/CA1079290A/en not_active Expired
- 1979-03-26 CA CA324,132A patent/CA1072966A/en not_active Expired
- 1979-03-26 CA CA324,130A patent/CA1086320A/en not_active Expired
-
1980
- 1980-08-14 HK HK433/80A patent/HK43380A/en unknown
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