ES449989A1 - Procedimiento para la obtencion de 9 alfa-fluoresteroides 11,12-insaturados. - Google Patents
Procedimiento para la obtencion de 9 alfa-fluoresteroides 11,12-insaturados.Info
- Publication number
- ES449989A1 ES449989A1 ES449989A ES449989A ES449989A1 ES 449989 A1 ES449989 A1 ES 449989A1 ES 449989 A ES449989 A ES 449989A ES 449989 A ES449989 A ES 449989A ES 449989 A1 ES449989 A1 ES 449989A1
- Authority
- ES
- Spain
- Prior art keywords
- unsaturated
- alpha
- compounds
- novel
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- -1 N,N-disubstituted aminosulphur trifluoride Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003128 pregnanes Chemical class 0.000 abstract 1
- 210000001541 thymus gland Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/009—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by only one oxygen atom doubly bound
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH962075A CH611631A5 (en) | 1975-07-23 | 1975-07-23 | Process for the preparation of 11,12-unsaturated 9alpha-fluorosteroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449989A1 true ES449989A1 (es) | 1977-12-01 |
Family
ID=4353884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449989A Expired ES449989A1 (es) | 1975-07-23 | 1976-07-21 | Procedimiento para la obtencion de 9 alfa-fluoresteroides 11,12-insaturados. |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5214761A (OSRAM) |
| AT (1) | AT353989B (OSRAM) |
| AU (1) | AU505846B2 (OSRAM) |
| BE (1) | BE844378A (OSRAM) |
| CH (1) | CH611631A5 (OSRAM) |
| DE (1) | DE2632550A1 (OSRAM) |
| DK (1) | DK329976A (OSRAM) |
| ES (1) | ES449989A1 (OSRAM) |
| FR (1) | FR2318644A1 (OSRAM) |
| GB (1) | GB1520356A (OSRAM) |
| IE (1) | IE43926B1 (OSRAM) |
| NL (1) | NL7608141A (OSRAM) |
| NZ (1) | NZ181538A (OSRAM) |
| SE (1) | SE7608369L (OSRAM) |
| ZA (1) | ZA764405B (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5423643A (en) * | 1977-07-22 | 1979-02-22 | Aikawa Tekko | Doctor blade stablizing apparatus |
| EP0029151B1 (en) * | 1979-11-16 | 1985-09-25 | STEROSYNT Ltd. | 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates |
| FI911202L (fi) * | 1990-12-28 | 1992-06-29 | Albany Int Corp | Schaberblad. |
-
1975
- 1975-07-23 CH CH962075A patent/CH611631A5/xx not_active IP Right Cessation
-
1976
- 1976-07-20 DE DE19762632550 patent/DE2632550A1/de active Pending
- 1976-07-21 ES ES449989A patent/ES449989A1/es not_active Expired
- 1976-07-21 FR FR7622212A patent/FR2318644A1/fr active Granted
- 1976-07-22 AT AT539376A patent/AT353989B/de not_active IP Right Cessation
- 1976-07-22 DK DK329976A patent/DK329976A/da unknown
- 1976-07-22 AU AU16121/76A patent/AU505846B2/en not_active Expired
- 1976-07-22 BE BE169116A patent/BE844378A/xx unknown
- 1976-07-22 NZ NZ181538A patent/NZ181538A/xx unknown
- 1976-07-22 SE SE7608369A patent/SE7608369L/xx unknown
- 1976-07-22 GB GB30616/76A patent/GB1520356A/en not_active Expired
- 1976-07-22 NL NL7608141A patent/NL7608141A/xx not_active Application Discontinuation
- 1976-07-22 ZA ZA764405A patent/ZA764405B/xx unknown
- 1976-07-22 IE IE1623/76A patent/IE43926B1/en unknown
- 1976-07-23 JP JP51087371A patent/JPS5214761A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2318644B1 (OSRAM) | 1978-12-15 |
| DK329976A (da) | 1977-01-24 |
| CH611631A5 (en) | 1979-06-15 |
| DE2632550A1 (de) | 1977-02-10 |
| AU505846B2 (en) | 1979-12-06 |
| SE7608369L (sv) | 1977-01-24 |
| NL7608141A (nl) | 1977-01-25 |
| GB1520356A (en) | 1978-08-09 |
| NZ181538A (en) | 1978-09-20 |
| AT353989B (de) | 1979-12-10 |
| JPS5214761A (en) | 1977-02-03 |
| ZA764405B (en) | 1977-08-31 |
| ATA539376A (de) | 1979-05-15 |
| FR2318644A1 (fr) | 1977-02-18 |
| BE844378A (fr) | 1977-01-24 |
| AU1612176A (en) | 1978-01-26 |
| IE43926L (en) | 1977-01-23 |
| IE43926B1 (en) | 1981-07-01 |
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