ES447114A1 - Nuevo procedimiento para la preparacion de derivados con en-lace peptidico. - Google Patents
Nuevo procedimiento para la preparacion de derivados con en-lace peptidico.Info
- Publication number
- ES447114A1 ES447114A1 ES447114A ES447114A ES447114A1 ES 447114 A1 ES447114 A1 ES 447114A1 ES 447114 A ES447114 A ES 447114A ES 447114 A ES447114 A ES 447114A ES 447114 A1 ES447114 A1 ES 447114A1
- Authority
- ES
- Spain
- Prior art keywords
- rho
- see formula
- acid derivatives
- isobutyric acid
- chlorophenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZCMYWRGSXUDLSC-UHFFFAOYSA-N ClC1=CC=C(ON(C(=O)N)C(C(C)C)=O)C=C1 Chemical compound ClC1=CC=C(ON(C(=O)N)C(C(C)C)=O)C=C1 ZCMYWRGSXUDLSC-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 150000001336 alkenes Chemical class 0.000 abstract 1
- 150000001345 alkine derivatives Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000005902 aminomethylation reaction Methods 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES447114A ES447114A1 (es) | 1976-04-15 | 1976-04-15 | Nuevo procedimiento para la preparacion de derivados con en-lace peptidico. |
| JP254077A JPS52128383A (en) | 1976-04-15 | 1977-01-14 | Method of producing ppchlorophenoxy isobutyric acid derivative |
| GB15327/77A GB1535683A (en) | 1976-04-15 | 1977-04-13 | Rho-chlorophenoxy isobutyric acid derivatives |
| DE2716374A DE2716374C2 (de) | 1976-04-15 | 1977-04-13 | N-2-(p-Chlorphenoxy)-isobutyryl-N'-morpholinmethylharnstoff, dessen Salze, Verfahren zu deren Herstellung und pharmazeutische Zubereitung |
| FR7711801A FR2348207A1 (fr) | 1976-04-15 | 1977-04-14 | Derive a liaison peptidique utilisable en medecine humaine et son procede de preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES447114A ES447114A1 (es) | 1976-04-15 | 1976-04-15 | Nuevo procedimiento para la preparacion de derivados con en-lace peptidico. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES447114A1 true ES447114A1 (es) | 1977-11-01 |
Family
ID=8471384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES447114A Expired ES447114A1 (es) | 1976-04-15 | 1976-04-15 | Nuevo procedimiento para la preparacion de derivados con en-lace peptidico. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS52128383A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2716374C2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES447114A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2348207A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1535683A (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES472295A1 (es) * | 1978-08-02 | 1979-02-16 | Invest Tecnica Aplicada | Procedimiento de obtencion de nuevas acilureas con actividadfarmacologica |
| CA2052014A1 (en) * | 1990-10-19 | 1992-04-20 | Henry Y. Pan | Method for preventing diabetic complications employing a cholesterol lowering drug alone or in combination with an ace inhibitor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1296513B (de) * | 1965-12-30 | 1969-05-29 | Adox Du Pont Fotowerke | Verfahren zum Haerten von gelatinehaltigen photographischen Schichten, insbesondere Halogensilberemulsionsschichten |
| US3927092A (en) * | 1968-06-24 | 1975-12-16 | Merck & Co Inc | Amides of 2-{8 halophenoxy (or halophenylthio){9 -alkanoic acids |
| DE1936282A1 (de) * | 1969-07-17 | 1971-01-28 | Ruhrchemie Ag | Verfahren zur Herstellung von N,N'-disubstituierten Harnstoffen und Thioharnstoffen |
| FR2187311B1 (cg-RX-API-DMAC7.html) * | 1972-06-02 | 1975-06-20 | Bouchara Emile |
-
1976
- 1976-04-15 ES ES447114A patent/ES447114A1/es not_active Expired
-
1977
- 1977-01-14 JP JP254077A patent/JPS52128383A/ja active Pending
- 1977-04-13 DE DE2716374A patent/DE2716374C2/de not_active Expired
- 1977-04-13 GB GB15327/77A patent/GB1535683A/en not_active Expired
- 1977-04-14 FR FR7711801A patent/FR2348207A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2716374C2 (de) | 1986-09-25 |
| FR2348207B1 (cg-RX-API-DMAC7.html) | 1980-02-08 |
| FR2348207A1 (fr) | 1977-11-10 |
| GB1535683A (en) | 1978-12-13 |
| DE2716374A1 (de) | 1977-11-03 |
| JPS52128383A (en) | 1977-10-27 |
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