ES446387A1 - Procedimiento para preparar sales amonicas de acido 6-fosfi-toamidopenicilanico y acido 7-fosfitoamidocefalosporanico - Google Patents

Procedimiento para preparar sales amonicas de acido 6-fosfi-toamidopenicilanico y acido 7-fosfitoamidocefalosporanico

Info

Publication number
ES446387A1
ES446387A1 ES446387A ES446387A ES446387A1 ES 446387 A1 ES446387 A1 ES 446387A1 ES 446387 A ES446387 A ES 446387A ES 446387 A ES446387 A ES 446387A ES 446387 A1 ES446387 A1 ES 446387A1
Authority
ES
Spain
Prior art keywords
cephem compounds
penam
preparation
ammonium salts
secondary ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES446387A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1278875A external-priority patent/GB1546385A/en
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of ES446387A1 publication Critical patent/ES446387A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65611—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. penicillins and analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Fosfitoamidas particularmente valiosas para utilizarse en la reacción en la cual el grupo 7- amino de ésteres de ácido 7-aminocefalosporánico (7-ACA) se acila con un haluro de acilo. Enpresencia de bases, tales como ésteres, se isomerizan fácilmente con lo cual los compuestos 3-cefem valiosos se convierten en compuestos 2-cefem
ES446387A 1975-03-26 1976-03-26 Procedimiento para preparar sales amonicas de acido 6-fosfi-toamidopenicilanico y acido 7-fosfitoamidocefalosporanico Expired ES446387A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1278875A GB1546385A (en) 1975-03-26 1975-03-26 Process for the preparation of phosphorus derivatives of secondary ammonium salts of penam and cephem compounds
GB2682675 1975-06-24

Publications (1)

Publication Number Publication Date
ES446387A1 true ES446387A1 (es) 1979-06-01

Family

ID=26249265

Family Applications (1)

Application Number Title Priority Date Filing Date
ES446387A Expired ES446387A1 (es) 1975-03-26 1976-03-26 Procedimiento para preparar sales amonicas de acido 6-fosfi-toamidopenicilanico y acido 7-fosfitoamidocefalosporanico

Country Status (12)

Country Link
US (1) US4082745A (es)
JP (1) JPS51118791A (es)
CH (1) CH614450A5 (es)
DE (1) DE2612523A1 (es)
DK (1) DK140989B (es)
ES (1) ES446387A1 (es)
FI (1) FI760756A (es)
FR (1) FR2305439A1 (es)
NL (1) NL7603231A (es)
NO (1) NO761053L (es)
PT (1) PT64936B (es)
SE (1) SE7603560L (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926954A (en) * 1970-05-27 1975-12-16 Erwin Kiesewetter Preparation of salts of carboxylic acids containing a beta-lactam groups
US3962215A (en) * 1971-10-04 1976-06-08 American Home Products Corporation Intermediates for preparing semi-synthetic penicillins and processes relating thereto
BE791099A (fr) * 1971-11-09 1973-05-08 American Home Prod Intermediaires pour la production de penicillines semi-synthetiques et procedes pour les obtenir
US3994911A (en) * 1971-11-09 1976-11-30 American Home Products Corporation Intermediate for producing semi-synthetic penicillins and cephalosporins
US3932391A (en) * 1972-10-02 1976-01-13 American Home Products Corporation Cephalosporin isocyanates
GB1459999A (en) * 1972-12-27 1976-12-31 Novo Industri As Penicillin and cephalosporin intermediates
US3953436A (en) * 1974-04-19 1976-04-27 Eli Lilly And Company 3,4-Dicarboxycephalosporins and derivatives

Also Published As

Publication number Publication date
NO761053L (es) 1976-09-28
FI760756A (es) 1976-09-27
DK140989C (es) 1980-06-02
PT64936B (en) 1977-08-25
NL7603231A (nl) 1976-09-28
CH614450A5 (es) 1979-11-30
PT64936A (en) 1976-04-01
FR2305439A1 (fr) 1976-10-22
US4082745A (en) 1978-04-04
DK136276A (es) 1976-09-27
SE7603560L (sv) 1976-09-27
DE2612523A1 (de) 1976-10-14
DK140989B (da) 1979-12-17
JPS51118791A (en) 1976-10-18

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