ES445913A1 - Un procedimiento para la preparacion de una sal dibasica farmaceuticamente aceptable de m. m. 17880. - Google Patents
Un procedimiento para la preparacion de una sal dibasica farmaceuticamente aceptable de m. m. 17880.Info
- Publication number
- ES445913A1 ES445913A1 ES445913A ES445913A ES445913A1 ES 445913 A1 ES445913 A1 ES 445913A1 ES 445913 A ES445913 A ES 445913A ES 445913 A ES445913 A ES 445913A ES 445913 A1 ES445913 A1 ES 445913A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- pharmaceutically acceptable
- dibasic salt
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 108090000204 Dipeptidase 1 Proteins 0.000 abstract 1
- 241000218589 Streptomyces olivaceus Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 102000006635 beta-lactamase Human genes 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/58—Streptomyces olivaceus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Enzymes And Modification Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB10914/75A GB1483142A (en) | 1975-03-15 | 1975-03-15 | Streptomycetal antibiotic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES445913A1 true ES445913A1 (es) | 1977-08-16 |
Family
ID=9976621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES445913A Expired ES445913A1 (es) | 1975-03-15 | 1976-03-09 | Un procedimiento para la preparacion de una sal dibasica farmaceuticamente aceptable de m. m. 17880. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4261977A (en:Method) |
| JP (1) | JPS599155B2 (en:Method) |
| AR (1) | AR208765A1 (en:Method) |
| AT (1) | AT355718B (en:Method) |
| AU (1) | AU502846B2 (en:Method) |
| BE (1) | BE839324A (en:Method) |
| CA (1) | CA1058540A (en:Method) |
| CH (1) | CH603792A5 (en:Method) |
| DD (1) | DD124121A5 (en:Method) |
| DE (1) | DE2609766A1 (en:Method) |
| DK (1) | DK139532B (en:Method) |
| ES (1) | ES445913A1 (en:Method) |
| FI (1) | FI55216C (en:Method) |
| FR (1) | FR2304351A1 (en:Method) |
| GB (1) | GB1483142A (en:Method) |
| GR (1) | GR59308B (en:Method) |
| HU (1) | HU175339B (en:Method) |
| IE (1) | IE42489B1 (en:Method) |
| IL (1) | IL49125A (en:Method) |
| MX (1) | MX3674E (en:Method) |
| NL (1) | NL7602671A (en:Method) |
| NO (1) | NO144674C (en:Method) |
| NZ (1) | NZ180167A (en:Method) |
| PH (1) | PH14828A (en:Method) |
| SE (1) | SE7603165L (en:Method) |
| SU (1) | SU581881A3 (en:Method) |
| YU (1) | YU63976A (en:Method) |
| ZA (1) | ZA761370B (en:Method) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165379A (en) * | 1975-11-21 | 1979-08-21 | Merck & Co., Inc. | N-acetyl thienamycin |
| US4839352A (en) * | 1975-11-21 | 1989-06-13 | Merck & Co., Inc. | N-acyl derivatives of thienamycin |
| US4162324A (en) * | 1975-11-21 | 1979-07-24 | Merck & Co., Inc. | Antibiotics 890A1 and 890A3 |
| DK487977A (da) * | 1976-11-17 | 1978-05-18 | Merck & Co Inc | Fremgangsmaade til fremstilling af et antiotisk stof |
| US4264736A (en) * | 1976-11-17 | 1981-04-28 | Merck & Co., Inc. | Antibiotic 890A10 |
| JPS53109997A (en) * | 1977-03-04 | 1978-09-26 | Sankyo Co Ltd | Antibiotic substance no.17927 a2 |
| EP0002564B1 (en) * | 1977-11-12 | 1984-06-20 | Beecham Group Plc | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates |
| US4220639A (en) * | 1978-02-14 | 1980-09-02 | Meiji Seika Kaisha, Ltd. | Antibiotics SF-2050 and SF-2050B substances and production and use thereof |
| JPS55136282A (en) | 1979-04-06 | 1980-10-23 | Shionogi & Co Ltd | Novel antibiotic pa-31088-4 |
| US4530791A (en) * | 1979-04-16 | 1985-07-23 | Kowa Co., Ltd. | β-Lactam antibiotics |
| US4409147A (en) * | 1980-03-10 | 1983-10-11 | Takeda Chemical Industries, Ltd. | Carbapenem compounds and their production |
-
1975
- 1975-03-15 GB GB10914/75A patent/GB1483142A/en not_active Expired
-
1976
- 1976-02-26 IE IE379/76A patent/IE42489B1/en unknown
- 1976-03-01 GR GR50192A patent/GR59308B/el unknown
- 1976-03-01 NO NO760681A patent/NO144674C/no unknown
- 1976-03-01 IL IL49125A patent/IL49125A/xx unknown
- 1976-03-02 NZ NZ180167A patent/NZ180167A/xx unknown
- 1976-03-05 ZA ZA761370A patent/ZA761370B/xx unknown
- 1976-03-05 FR FR7606248A patent/FR2304351A1/fr active Granted
- 1976-03-08 BE BE164961A patent/BE839324A/xx not_active IP Right Cessation
- 1976-03-09 DE DE19762609766 patent/DE2609766A1/de not_active Withdrawn
- 1976-03-09 ES ES445913A patent/ES445913A1/es not_active Expired
- 1976-03-10 SE SE7603165A patent/SE7603165L/xx not_active Application Discontinuation
- 1976-03-11 HU HU76BE1256A patent/HU175339B/hu unknown
- 1976-03-11 MX MX7663U patent/MX3674E/es unknown
- 1976-03-11 YU YU00639/76A patent/YU63976A/xx unknown
- 1976-03-12 SU SU7602333503A patent/SU581881A3/ru active
- 1976-03-12 CA CA247,809A patent/CA1058540A/en not_active Expired
- 1976-03-12 AT AT183176A patent/AT355718B/de not_active IP Right Cessation
- 1976-03-12 DK DK107676AA patent/DK139532B/da unknown
- 1976-03-15 NL NL7602671A patent/NL7602671A/xx not_active Application Discontinuation
- 1976-03-15 PH PH18211A patent/PH14828A/en unknown
- 1976-03-15 AR AR262550A patent/AR208765A1/es active
- 1976-03-15 DD DD191856A patent/DD124121A5/xx unknown
- 1976-03-15 FI FI760674A patent/FI55216C/fi not_active IP Right Cessation
- 1976-03-15 AU AU12014/76A patent/AU502846B2/en not_active Expired
- 1976-03-15 JP JP51028543A patent/JPS599155B2/ja not_active Expired
- 1976-03-15 CH CH318376A patent/CH603792A5/xx not_active IP Right Cessation
-
1978
- 1978-08-29 US US05/937,736 patent/US4261977A/en not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |