ES445381A1 - Un procedimiento de convertir asimetricamente la 2-deutero- 3-fluor-1-alanina en el correspondiente isomero d. - Google Patents
Un procedimiento de convertir asimetricamente la 2-deutero- 3-fluor-1-alanina en el correspondiente isomero d.Info
- Publication number
- ES445381A1 ES445381A1 ES445381A ES445381A ES445381A1 ES 445381 A1 ES445381 A1 ES 445381A1 ES 445381 A ES445381 A ES 445381A ES 445381 A ES445381 A ES 445381A ES 445381 A1 ES445381 A1 ES 445381A1
- Authority
- ES
- Spain
- Prior art keywords
- deutero
- fluoro
- alanine
- isomer
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UYTSRQMXRROFPU-LIIDHCAMSA-N (2s)-2-amino-2-deuterio-3-fluoropropanoic acid Chemical compound FC[C@](N)([2H])C(O)=O UYTSRQMXRROFPU-LIIDHCAMSA-N 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000010288 sodium nitrite Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
- C07C53/21—Acids containing three or more carbon atoms containing fluorine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
- C07C59/19—Pyruvic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/552,474 US3950411A (en) | 1972-02-03 | 1975-02-24 | Processes for asymmetric conversion of 3-fluoro-L-alanine and 2-deutero-3-fluoro-L-alanine to their D-isomers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES445381A1 true ES445381A1 (es) | 1977-06-01 |
Family
ID=24205490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES445381A Expired ES445381A1 (es) | 1975-02-24 | 1976-02-20 | Un procedimiento de convertir asimetricamente la 2-deutero- 3-fluor-1-alanina en el correspondiente isomero d. |
Country Status (21)
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3880922A (en) * | 1972-02-03 | 1975-04-29 | Merck & Co Inc | Process for preparing 3-fluoro-D-alanine by asymmetric rearrangement of 2-(azidocarbonyl)-3-fluoro-propionic ester or nitrile |
-
1976
- 1976-01-01 AR AR262279A patent/AR207277A1/es active
- 1976-02-09 FI FI760302A patent/FI760302A7/fi not_active Application Discontinuation
- 1976-02-10 SE SE7601423A patent/SE7601423L/xx unknown
- 1976-02-11 DK DK55976*#A patent/DK55976A/da unknown
- 1976-02-12 NO NO760448A patent/NO760448L/no unknown
- 1976-02-13 NL NL7601511A patent/NL7601511A/xx not_active Application Discontinuation
- 1976-02-16 PT PT64805A patent/PT64805B/pt unknown
- 1976-02-17 AU AU11178/76A patent/AU500536B2/en not_active Expired
- 1976-02-17 GR GR50072A patent/GR59306B/el unknown
- 1976-02-17 CH CH193076A patent/CH620194A5/de not_active IP Right Cessation
- 1976-02-18 CA CA246,060A patent/CA1045157A/en not_active Expired
- 1976-02-19 YU YU00418/76A patent/YU41876A/xx unknown
- 1976-02-19 GB GB6655/76A patent/GB1488332A/en not_active Expired
- 1976-02-20 FR FR7604715A patent/FR2301513A1/fr active Granted
- 1976-02-20 IE IE335/76A patent/IE43351B1/en unknown
- 1976-02-20 ES ES445381A patent/ES445381A1/es not_active Expired
- 1976-02-23 DE DE19762607252 patent/DE2607252A1/de not_active Withdrawn
- 1976-02-23 CS CS761182A patent/CS199274B2/cs unknown
- 1976-02-23 ZA ZA761045A patent/ZA761045B/xx unknown
- 1976-02-24 JP JP51018580A patent/JPS51110513A/ja active Pending
- 1976-02-24 HU HU76ME1954A patent/HU173362B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK55976A (da) | 1976-08-25 |
| FR2301513A1 (fr) | 1976-09-17 |
| AR207277A1 (es) | 1976-09-22 |
| YU41876A (en) | 1982-02-28 |
| FI760302A7 (enrdf_load_stackoverflow) | 1976-08-25 |
| CS199274B2 (en) | 1980-07-31 |
| HU173362B (hu) | 1979-04-28 |
| NO760448L (enrdf_load_stackoverflow) | 1976-08-25 |
| PT64805A (en) | 1976-03-01 |
| AU1117876A (en) | 1977-08-25 |
| SE7601423L (sv) | 1976-08-25 |
| DE2607252A1 (de) | 1976-09-02 |
| GR59306B (en) | 1977-12-12 |
| CH620194A5 (en) | 1980-11-14 |
| NL7601511A (nl) | 1976-08-26 |
| AU500536B2 (en) | 1979-05-24 |
| IE43351B1 (en) | 1981-02-11 |
| CA1045157A (en) | 1978-12-26 |
| IE43351L (en) | 1976-08-21 |
| ZA761045B (en) | 1977-09-28 |
| GB1488332A (en) | 1977-10-12 |
| JPS51110513A (enrdf_load_stackoverflow) | 1976-09-30 |
| FR2301513B1 (enrdf_load_stackoverflow) | 1979-02-02 |
| PT64805B (en) | 1978-02-06 |
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