IE43351B1 - Processes for asymmetric conversion of 3-fluoro-l-alanine and 2-deutero-3-fluoro-l-alanine to their d-isomers - Google Patents

Processes for asymmetric conversion of 3-fluoro-l-alanine and 2-deutero-3-fluoro-l-alanine to their d-isomers

Info

Publication number
IE43351B1
IE43351B1 IE335/76A IE33576A IE43351B1 IE 43351 B1 IE43351 B1 IE 43351B1 IE 335/76 A IE335/76 A IE 335/76A IE 33576 A IE33576 A IE 33576A IE 43351 B1 IE43351 B1 IE 43351B1
Authority
IE
Ireland
Prior art keywords
deutero
fluoro
alanine
acid
halo
Prior art date
Application number
IE335/76A
Other languages
English (en)
Other versions
IE43351L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/552,474 external-priority patent/US3950411A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE43351L publication Critical patent/IE43351L/xx
Publication of IE43351B1 publication Critical patent/IE43351B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00Derivatives of isocyanic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/19Acids containing three or more carbon atoms
    • C07C53/21Acids containing three or more carbon atoms containing fluorine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185Saturated compounds having only one carboxyl group and containing keto groups
    • C07C59/19Pyruvic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE335/76A 1975-02-24 1976-02-20 Processes for asymmetric conversion of 3-fluoro-l-alanine and 2-deutero-3-fluoro-l-alanine to their d-isomers IE43351B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/552,474 US3950411A (en) 1972-02-03 1975-02-24 Processes for asymmetric conversion of 3-fluoro-L-alanine and 2-deutero-3-fluoro-L-alanine to their D-isomers

Publications (2)

Publication Number Publication Date
IE43351L IE43351L (en) 1976-08-21
IE43351B1 true IE43351B1 (en) 1981-02-11

Family

ID=24205490

Family Applications (1)

Application Number Title Priority Date Filing Date
IE335/76A IE43351B1 (en) 1975-02-24 1976-02-20 Processes for asymmetric conversion of 3-fluoro-l-alanine and 2-deutero-3-fluoro-l-alanine to their d-isomers

Country Status (21)

Country Link
JP (1) JPS51110513A (enrdf_load_stackoverflow)
AR (1) AR207277A1 (enrdf_load_stackoverflow)
AU (1) AU500536B2 (enrdf_load_stackoverflow)
CA (1) CA1045157A (enrdf_load_stackoverflow)
CH (1) CH620194A5 (enrdf_load_stackoverflow)
CS (1) CS199274B2 (enrdf_load_stackoverflow)
DE (1) DE2607252A1 (enrdf_load_stackoverflow)
DK (1) DK55976A (enrdf_load_stackoverflow)
ES (1) ES445381A1 (enrdf_load_stackoverflow)
FI (1) FI760302A7 (enrdf_load_stackoverflow)
FR (1) FR2301513A1 (enrdf_load_stackoverflow)
GB (1) GB1488332A (enrdf_load_stackoverflow)
GR (1) GR59306B (enrdf_load_stackoverflow)
HU (1) HU173362B (enrdf_load_stackoverflow)
IE (1) IE43351B1 (enrdf_load_stackoverflow)
NL (1) NL7601511A (enrdf_load_stackoverflow)
NO (1) NO760448L (enrdf_load_stackoverflow)
PT (1) PT64805B (enrdf_load_stackoverflow)
SE (1) SE7601423L (enrdf_load_stackoverflow)
YU (1) YU41876A (enrdf_load_stackoverflow)
ZA (1) ZA761045B (enrdf_load_stackoverflow)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880922A (en) * 1972-02-03 1975-04-29 Merck & Co Inc Process for preparing 3-fluoro-D-alanine by asymmetric rearrangement of 2-(azidocarbonyl)-3-fluoro-propionic ester or nitrile

Also Published As

Publication number Publication date
DK55976A (da) 1976-08-25
FR2301513A1 (fr) 1976-09-17
AR207277A1 (es) 1976-09-22
YU41876A (en) 1982-02-28
FI760302A7 (enrdf_load_stackoverflow) 1976-08-25
CS199274B2 (en) 1980-07-31
HU173362B (hu) 1979-04-28
NO760448L (enrdf_load_stackoverflow) 1976-08-25
PT64805A (en) 1976-03-01
AU1117876A (en) 1977-08-25
SE7601423L (sv) 1976-08-25
DE2607252A1 (de) 1976-09-02
ES445381A1 (es) 1977-06-01
GR59306B (en) 1977-12-12
CH620194A5 (en) 1980-11-14
NL7601511A (nl) 1976-08-26
AU500536B2 (en) 1979-05-24
CA1045157A (en) 1978-12-26
IE43351L (en) 1976-08-21
ZA761045B (en) 1977-09-28
GB1488332A (en) 1977-10-12
JPS51110513A (enrdf_load_stackoverflow) 1976-09-30
FR2301513B1 (enrdf_load_stackoverflow) 1979-02-02
PT64805B (en) 1978-02-06

Similar Documents

Publication Publication Date Title
DE69619809T2 (de) Verfahren zur herstellung von (s)-3-(aminoethyl)-5-metylhexansäure
IE65907B1 (en) New 3-hydroxy-2-cyclobuten-1-one salts their preparation and use
US2489232A (en) Synthesis of biotin
IE47910B1 (en) Optically-active ethers of -cyano-3-phenoxybenzyl alcohol
US3032585A (en) Process for the production of p-bis-(2-chloroethyl)-aminophenylalanine
US3153092A (en) 1-methyl-2-phenylcyclopropylamine derivatives
EP0594099A1 (en) Process for the purification of crude clavulanic acid
NO821088L (no) Fremgangsmaate for fremstilling av d-2-(6-metoksy-2-naftyl)-propionsyre
IE43351B1 (en) Processes for asymmetric conversion of 3-fluoro-l-alanine and 2-deutero-3-fluoro-l-alanine to their d-isomers
US2786077A (en) Desdimethylaminotetracyclines and process
Beard et al. 2-Phenylcyclobutylamine
US3972921A (en) Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts
US4542235A (en) Method for producing an optically active 2,2-dimethylcyclopropanecarboxylic acid
US3059020A (en) Substituted cyclopropylamines and cyclopropylcarbamates
SU458976A3 (ru) Способ получени -(транс-4оксициклогексил-2-амино-3,5дибромбензил)-амина
US3880922A (en) Process for preparing 3-fluoro-D-alanine by asymmetric rearrangement of 2-(azidocarbonyl)-3-fluoro-propionic ester or nitrile
US3299095A (en) 1-benzyl tetramic acid derivatives
US3950411A (en) Processes for asymmetric conversion of 3-fluoro-L-alanine and 2-deutero-3-fluoro-L-alanine to their D-isomers
US2906772A (en) Resolution of di-2, 2-diphenyl-3-methyl-4-dimethylaminobutyronitrile
IE44046B1 (en) Improved method of synthesis of trans-2-phenylcycloprpylamine
US3541139A (en) Resolution of racemic alpha-hydroxy-beta,beta-dimethyl-gamma- butyrolactone
EP0772584B1 (de) Verfahren zur herstellung von selegilin
US3014925A (en) Unsaturated mevalonic acid
US2701798A (en) Ch-cha
HU186528B (en) Process for producing tetronnoic acid