ES442910A1 - Treatment of depressive states and Parkinson{3 s disease - Google Patents

Treatment of depressive states and Parkinson{3 s disease

Info

Publication number
ES442910A1
ES442910A1 ES442910A ES442910A ES442910A1 ES 442910 A1 ES442910 A1 ES 442910A1 ES 442910 A ES442910 A ES 442910A ES 442910 A ES442910 A ES 442910A ES 442910 A1 ES442910 A1 ES 442910A1
Authority
ES
Spain
Prior art keywords
parkinson
group
disease
depressive states
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES442910A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7440233A external-priority patent/FR2293931A1/en
Priority claimed from FR7532483A external-priority patent/FR2328468A2/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES442910A1 publication Critical patent/ES442910A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Novel compositions having antidepressive, antiemetic and anti-Parkinson activities comprising an effective amount of at least one compound selected from the group consisting of 3-(4'-piperidyl)-indoles of the formula WHEREIN R is selected from the group consisting of hydrogen and alkoxy of 1 to 5 carbon atoms and R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts and a pharmaceutical carrier and to a method of treating depressive states and Parkinson disease in warm-blooded animals and humans.
ES442910A 1974-12-09 1975-11-24 Treatment of depressive states and Parkinson{3 s disease Expired ES442910A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7440233A FR2293931A1 (en) 1974-12-09 1974-12-09 Antidepressant, antiemetic and anti Parkinson 3-(4-piperidyl) indoles - e.g. 5-methoxy-3-(4-piperidyl)indole
FR7532483A FR2328468A2 (en) 1975-10-23 1975-10-23 Antidepressant, antiemetic and anti Parkinson 3-(4-piperidyl) indoles - e.g. 5-methoxy-3-(4-piperidyl)indole

Publications (1)

Publication Number Publication Date
ES442910A1 true ES442910A1 (en) 1979-05-01

Family

ID=26218630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES442910A Expired ES442910A1 (en) 1974-12-09 1975-11-24 Treatment of depressive states and Parkinson{3 s disease

Country Status (15)

Country Link
US (1) US3993764A (en)
JP (1) JPS5186475A (en)
AU (1) AU498955B2 (en)
CA (1) CA1089766A (en)
CH (1) CH605915A5 (en)
DE (1) DE2552869C2 (en)
DK (1) DK139580B (en)
ES (1) ES442910A1 (en)
GB (2) GB1529329A (en)
IE (1) IE42618B1 (en)
IL (1) IL48508A (en)
LU (1) LU73947A1 (en)
MX (1) MX3046E (en)
NL (1) NL7514255A (en)
SE (1) SE408422B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362628A1 (en) * 1976-08-26 1978-03-24 Roussel Uclaf NEW DERIVATIVES OF PIPERIDYL-INDOLE AND THEIR SALTS, METHOD OF PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS
FR2421899A1 (en) * 1978-01-16 1979-11-02 Roussel Uclaf NEW TETRAHYDROPYRIDINYL-INDOLE DERIVATIVES AND THEIR SALTS, THE PREPARATION PROCESS AND THE MEDICINAL APPLICATION OF THESE NEW PRODUCTS
FR2444678A2 (en) * 1978-12-22 1980-07-18 Roussel Uclaf NOVEL PROCESS FOR THE PREPARATION OF PIPERIDYL-INDOLE DERIVATIVES AND THEIR SALTS
FR2460947A1 (en) * 1979-07-13 1981-01-30 Roussel Uclaf NOVEL N-SUBSTITUTED TETRAHYDROPYRIDINYL-INDOLE DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING SAME
SE8004129L (en) * 1979-07-13 1981-01-14 Roussel Uclaf NEW TETRAHYDROPYRIDIN-4-YL-INDOLD DERIVATIVES AND SALTS THEREOF, PREPARATION AND USE THEREOF AS A MEDICINAL PRODUCT AND COMPOSITIONS CONTAINING THESE COMPOUNDS
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
DK733788A (en) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co INDOLYL PIPERIDE INGREDIENTS AND PROCEDURES FOR PREPARING THEREOF
MX19185A (en) * 1989-01-20 1993-12-01 Pfizer PROCEDURE FOR PREPARING 3- (1,2,5,6-TRETRAHIDROPIRIDIL) -PIRROLOPIRIDINAS.
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
DK36291D0 (en) * 1991-03-01 1991-03-01 Lundbeck & Co As H APPLICATION OF PIPERIDYL-SUBSTITUTED INDEX DERIVATIVES FOR TREATMENT OF COGNITIVE DISORDERS
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2193584B1 (en) * 1972-07-28 1975-08-08 Roussel Uclaf

Also Published As

Publication number Publication date
SE408422B (en) 1979-06-11
IE42618L (en) 1976-06-09
IE42618B1 (en) 1980-09-10
IL48508A (en) 1979-10-31
JPS5186475A (en) 1976-07-29
DK139580C (en) 1979-08-27
NL7514255A (en) 1976-06-11
CA1089766A (en) 1980-11-18
MX3046E (en) 1980-03-04
DK139580B (en) 1979-03-12
DE2552869C2 (en) 1981-09-17
IL48508A0 (en) 1976-01-30
DE2552869A1 (en) 1976-06-10
GB1529329A (en) 1978-10-18
CH605915A5 (en) 1978-10-13
AU8717375A (en) 1977-06-09
DK553175A (en) 1976-06-10
LU73947A1 (en) 1976-11-11
GB1529330A (en) 1978-10-18
SE7513391L (en) 1976-06-10
US3993764A (en) 1976-11-23
AU498955B2 (en) 1979-03-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103