ES439488A1 - Procedure for the obtaining of new pregnan-21-aldehydes and their derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of new pregnan-21-aldehydes and their derivatives. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES439488A1
ES439488A1 ES439488A ES439488A ES439488A1 ES 439488 A1 ES439488 A1 ES 439488A1 ES 439488 A ES439488 A ES 439488A ES 439488 A ES439488 A ES 439488A ES 439488 A1 ES439488 A1 ES 439488A1
Authority
ES
Spain
Prior art keywords
formula
group
hydroxy group
esterified
signifies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES439488A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH313472A external-priority patent/CH592113A5/xx
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES439488A1 publication Critical patent/ES439488A1/en
Expired legal-status Critical Current

Links

Abstract

Procedure for obtaining new pregnan-21-aldehydes and their derivatives of formula ** (See formula) ** wherein R1 and R2 together signify an oxo group or, in each case, a free, esterified or esterified hydroxy group, R3 signifies a free or esterified hydroxy group, R4 signifies an oxo group or a hydroxy group in β together with a hydrogen atom and one of the radicals R5 and R6 means one fluorine atom and the other hydrogen or a fluorine atom, characterized in that a compound of formula ** (See formula) ** wherein R1, R2, R3, R4, R5 and R6 have the meaning indicated above, optionally under transient protection of the 11-hydroxy and/or 20-oxo group, chlorine is added to the double bond 1.2 and the compound 1,2-dichloro obtained dissociates hydrochloric acid and, if desired, the obtained compounds of formula (X), where R1 and R2 together form a gold group or at least one of the radicals R1 and R2 signifies a free hydroxy group, is treated with esterifying or etheating agents, or the compounds obtained of formula (I), wherein at least one of the residues R1 and R2 means an esterified or esterified hydroxy group, it is treated with hydrolyzing means, or in the obtained compounds, where R4 signifies a free hydroxy group, this is oxidized to the oxo group. (Machine-translation by Google Translate, not legally binding)
ES439488A 1972-03-03 1975-07-16 Procedure for the obtaining of new pregnan-21-aldehydes and their derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES439488A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH313472A CH592113A5 (en) 1972-03-03 1972-03-03
CH132573 1973-01-30

Publications (1)

Publication Number Publication Date
ES439488A1 true ES439488A1 (en) 1977-09-16

Family

ID=25687335

Family Applications (1)

Application Number Title Priority Date Filing Date
ES439488A Expired ES439488A1 (en) 1972-03-03 1975-07-16 Procedure for the obtaining of new pregnan-21-aldehydes and their derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES439488A1 (en)

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