ES437262A1 - Manufacture of diazepin compound - Google Patents

Manufacture of diazepin compound

Info

Publication number
ES437262A1
ES437262A1 ES437262A ES437262A ES437262A1 ES 437262 A1 ES437262 A1 ES 437262A1 ES 437262 A ES437262 A ES 437262A ES 437262 A ES437262 A ES 437262A ES 437262 A1 ES437262 A1 ES 437262A1
Authority
ES
Spain
Prior art keywords
chlorine
bromine atom
group
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437262A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES437262A1 publication Critical patent/ES437262A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Abstract

Procedure for the preparation of new substituted 6-aryl-4H-s-triazolo- [3,4c] -tiene - [2,3e] -l, 4-diazepines of the general formula **(See formula)** where it means a hydrogen, chlorine or bromine atom or an alcohol group with 1 to 4 carbon atoms; R2 signifies a hydrogen, fluorine, chlorine or bromine atom, the nitro group or the trifluoromethyl group; and R3 means a chlorine or bromine atom, an apt alkoxy or alcoholic group with 1 to 3 carbon atoms, as well as their physiologically compatible acid addition salts, characterized in that: it is subjected to chlorination or bromination to a compound of the formula **(See formula)** wherein R1 and R2 have the indicated meanings and, if desired, the chlorine or bromine atom is replaced by an alkoxy or alcoholmercapto group; and because eventually a compound of formula I thus obtained is transformed into a physiologically harmless acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES437262A 1974-07-20 1975-04-30 Manufacture of diazepin compound Expired ES437262A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2435041A DE2435041C3 (en) 1974-07-20 1974-07-20 8-Substituted 6-aryl-4H-s-triazolo [3,4c] thieno [23e] 1,4-diazepines, process for their preparation, their use in medicaments and pharmaceutical preparations containing them

Publications (1)

Publication Number Publication Date
ES437262A1 true ES437262A1 (en) 1977-04-01

Family

ID=5921115

Family Applications (1)

Application Number Title Priority Date Filing Date
ES437262A Expired ES437262A1 (en) 1974-07-20 1975-04-30 Manufacture of diazepin compound

Country Status (8)

Country Link
JP (2) JPS6023116B2 (en)
AT (1) AT338810B (en)
DE (1) DE2435041C3 (en)
ES (1) ES437262A1 (en)
HK (1) HK46081A (en)
IT (1) IT7949468A0 (en)
PL (2) PL99670B1 (en)
ZA (1) ZA774316B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2699274B1 (en) * 1992-12-15 1995-01-13 Inst Francais Du Petrole Method and device for controlling a flow of particles in a conduit.
DE10116378C2 (en) * 2001-04-04 2003-05-28 Boehringer Ingelheim Pharma Process for the preparation of 6-aryl-4H-s-triazolo [3,4-c] thieno [2,3-e] -1,4-diazepines

Also Published As

Publication number Publication date
DE2435041B2 (en) 1977-08-04
DE2435041A1 (en) 1976-02-05
ATA101876A (en) 1977-01-15
JPS6023116B2 (en) 1985-06-05
JPS59108787A (en) 1984-06-23
IT7949468A0 (en) 1979-06-20
JPS5555192A (en) 1980-04-22
AT338810B (en) 1977-09-12
HK46081A (en) 1981-09-18
PL99670B1 (en) 1978-07-31
ZA774316B (en) 1977-09-28
PL99176B1 (en) 1978-06-30
DE2435041C3 (en) 1978-10-19
JPS6148840B2 (en) 1986-10-25

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