ES435620A1 - A procedure for the preparation of new derivatives of tolipomycinone. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new derivatives of tolipomycinone. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES435620A1
ES435620A1 ES435620A ES435620A ES435620A1 ES 435620 A1 ES435620 A1 ES 435620A1 ES 435620 A ES435620 A ES 435620A ES 435620 A ES435620 A ES 435620A ES 435620 A1 ES435620 A1 ES 435620A1
Authority
ES
Spain
Prior art keywords
formula
tolipomycinone
see formula
compound
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435620A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Farmaceutici SpA
Original Assignee
Alfa Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1167474A external-priority patent/GB1498033A/en
Application filed by Alfa Farmaceutici SpA filed Critical Alfa Farmaceutici SpA
Publication of ES435620A1 publication Critical patent/ES435620A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)

Abstract

A process for the preparation of new tolipomycinone derivatives of formula (II): ** (see formula) ** Wherein r represents an aliphatic hydrocarbon group whose chain of carbon atoms may be interrupted by one or more oxygen and/or sulfur and/or nitrogen atoms, and which may be substituted or unsubstituted; q represents one of the groups ** (see formula) ** (being r as defined above); and the groups: ** (see formula) ** A process comprising reacting tolipomycinone or, respectively, 16,17-dihydrotolipomycinone with a corresponding amine, thereby obtaining the compound of formula iii ** (see formula) ** Which is the compound of formula ii in which the group ** (see formula) ** And, if appropriate, reducing the product obtained having the formula iii to a compound in which the group ** (see formula) ** Thus giving a compound having the formula iv ** (see formula) ** Wherein r and q in formulas iii and iv are as defined above. (Machine-translation by Google Translate, not legally binding)
ES435620A 1974-03-15 1975-03-14 A procedure for the preparation of new derivatives of tolipomycinone. (Machine-translation by Google Translate, not legally binding) Expired ES435620A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1167474A GB1498033A (en) 1974-03-15 1974-03-15 Tolypomycinone derivatives and process for their preparation
GB4739874 1974-11-01

Publications (1)

Publication Number Publication Date
ES435620A1 true ES435620A1 (en) 1977-05-01

Family

ID=26248441

Family Applications (1)

Application Number Title Priority Date Filing Date
ES435620A Expired ES435620A1 (en) 1974-03-15 1975-03-14 A procedure for the preparation of new derivatives of tolipomycinone. (Machine-translation by Google Translate, not legally binding)

Country Status (14)

Country Link
JP (1) JPS5341680B2 (en)
AR (2) AR208540A1 (en)
AT (1) AT335610B (en)
CA (1) CA1063604A (en)
DE (1) DE2510931A1 (en)
DK (1) DK104075A (en)
ES (1) ES435620A1 (en)
FI (1) FI59101C (en)
FR (1) FR2263767A1 (en)
IT (1) IT1060152B (en)
LU (1) LU72029A1 (en)
NL (1) NL159986C (en)
PH (1) PH13558A (en)
SE (1) SE7502882L (en)

Also Published As

Publication number Publication date
DK104075A (en) 1975-09-16
NL159986C (en) 1979-09-17
PH13558A (en) 1980-06-26
IT1060152B (en) 1982-07-10
FI59101C (en) 1981-06-10
SE7502882L (en) 1975-09-16
LU72029A1 (en) 1976-02-04
NL7502980A (en) 1975-09-17
ATA195975A (en) 1976-07-15
AT335610B (en) 1977-03-25
JPS50157399A (en) 1975-12-19
FI59101B (en) 1981-02-27
DE2510931A1 (en) 1975-11-13
NL159986B (en) 1979-04-17
CA1063604A (en) 1979-10-02
AR213283A1 (en) 1979-01-15
FI750743A (en) 1975-09-16
FR2263767B1 (en) 1980-01-04
FR2263767A1 (en) 1975-10-10
AR208540A1 (en) 1977-02-15
JPS5341680B2 (en) 1978-11-06

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