ES431775A1 - Procedimiento para la preparacion de derivados de 1-fenil-2-aminoguanidina. - Google Patents
Procedimiento para la preparacion de derivados de 1-fenil-2-aminoguanidina.Info
- Publication number
- ES431775A1 ES431775A1 ES431775A ES431775A ES431775A1 ES 431775 A1 ES431775 A1 ES 431775A1 ES 431775 A ES431775 A ES 431775A ES 431775 A ES431775 A ES 431775A ES 431775 A1 ES431775 A1 ES 431775A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- alkoxy
- hydroxy
- stands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2,6-disubstituted phenyl-aminoguanidine compounds Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7315350A NL7315350A (nl) | 1973-11-09 | 1973-11-09 | Nieuwe aminoguanidine verbindingen. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES431775A1 true ES431775A1 (es) | 1976-12-16 |
Family
ID=19819967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES431775A Expired ES431775A1 (es) | 1973-11-09 | 1974-11-08 | Procedimiento para la preparacion de derivados de 1-fenil-2-aminoguanidina. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3972932A (en, 2012) |
| JP (1) | JPS5546389B2 (en, 2012) |
| AR (1) | AR205358A1 (en, 2012) |
| BE (1) | BE822019A (en, 2012) |
| CA (1) | CA1032962A (en, 2012) |
| CH (1) | CH616656A5 (en, 2012) |
| DE (1) | DE2452691A1 (en, 2012) |
| DK (1) | DK138791B (en, 2012) |
| ES (1) | ES431775A1 (en, 2012) |
| FI (1) | FI62064C (en, 2012) |
| FR (1) | FR2250521B1 (en, 2012) |
| GB (1) | GB1487852A (en, 2012) |
| HU (1) | HU171856B (en, 2012) |
| IE (1) | IE40409B1 (en, 2012) |
| NL (1) | NL7315350A (en, 2012) |
| SE (1) | SE420720B (en, 2012) |
| ZA (1) | ZA746701B (en, 2012) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4141992A (en) * | 1975-08-22 | 1979-02-27 | American Cyanamid Company | Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents |
| US4113776A (en) * | 1976-04-15 | 1978-09-12 | Hoffmann-La Roche Inc. | 1-(2-Aminoethyl)-3-(2,6-dihalophenyl)guanidines |
| HU190639B (en) * | 1983-12-12 | 1986-09-29 | Gyogyszerkutato Intezet Kv,Hu | Process for production of new aminoguanidin derivatives |
| ZA857153B (en) * | 1984-09-19 | 1986-05-28 | Ciba Geigy Ag | Substituted carbodiimides |
| EP0175649B1 (de) * | 1984-09-19 | 1991-01-02 | Ciba-Geigy Ag | Substituierte Carbodiimide |
| US5262568A (en) * | 1990-03-02 | 1993-11-16 | State Of Oregon | Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists |
| ES2181668T3 (es) | 1990-03-02 | 2003-03-01 | Oregon State | Guanidinas tri- y tetra-substituidas y su uso como antagonistas de aminoacido excitador. |
| ZA92944B (en) * | 1991-02-08 | 1993-08-10 | Cambridge Neuroscience Inc | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and methodology for identifying neurotransmitter release blockers |
| US5741661A (en) * | 1991-02-08 | 1998-04-21 | Cambridge Neuroscience, Inc. | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers |
| US5847006A (en) * | 1991-02-08 | 1998-12-08 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
| CA2163361C (en) * | 1993-05-27 | 2008-06-17 | Graham J. Durant | Therapeutic substituted guanidines |
| AU705487B2 (en) * | 1993-11-23 | 1999-05-20 | Cambridge Neuroscience, Inc. | Therapeutic substituted guanidines |
| JPH09509156A (ja) | 1994-02-03 | 1997-09-16 | ケンブリッジ・ニューロサイエンス・インコーポレーテッド | 治療用グアニジン類 |
| US6787569B1 (en) | 1994-02-03 | 2004-09-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
| US7351743B1 (en) | 1994-02-03 | 2008-04-01 | Wyeth | Therapeutic guanidines |
| US6143791A (en) * | 1994-02-03 | 2000-11-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
| JP4739695B2 (ja) * | 2004-06-07 | 2011-08-03 | 株式会社日本ファインケム | ５−アミノ―１―置換―１，２，４―トリアゾールの製造方法、及び該製造方法で得られるトリアゾール誘導体 |
| JP4564786B2 (ja) * | 2004-06-07 | 2010-10-20 | 株式会社日本ファインケム | １−置換―１―アミノグアニジン又はその塩、及びこれらの製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB800869A (en) * | 1955-09-28 | 1958-09-03 | Ici Ltd | Substituted amino-guanidines |
| NL7011683A (en, 2012) * | 1970-08-07 | 1972-02-09 |
-
1973
- 1973-11-09 NL NL7315350A patent/NL7315350A/xx not_active Application Discontinuation
-
1974
- 1974-01-01 AR AR256431A patent/AR205358A1/es active
- 1974-10-22 ZA ZA00746701A patent/ZA746701B/xx unknown
- 1974-10-22 IE IE2173/74A patent/IE40409B1/xx unknown
- 1974-10-23 GB GB45874/74A patent/GB1487852A/en not_active Expired
- 1974-10-24 US US05/517,554 patent/US3972932A/en not_active Expired - Lifetime
- 1974-11-06 DK DK579774AA patent/DK138791B/da unknown
- 1974-11-06 HU HU74AO00000394A patent/HU171856B/hu unknown
- 1974-11-06 CH CH1484974A patent/CH616656A5/de not_active IP Right Cessation
- 1974-11-06 DE DE19742452691 patent/DE2452691A1/de not_active Withdrawn
- 1974-11-07 FI FI3243/74A patent/FI62064C/fi active
- 1974-11-08 ES ES431775A patent/ES431775A1/es not_active Expired
- 1974-11-08 CA CA213,351A patent/CA1032962A/en not_active Expired
- 1974-11-08 JP JP12882574A patent/JPS5546389B2/ja not_active Expired
- 1974-11-08 SE SE7414045A patent/SE420720B/xx unknown
- 1974-11-08 BE BE150356A patent/BE822019A/xx unknown
- 1974-11-08 FR FR7437192A patent/FR2250521B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA746701B (en) | 1975-11-26 |
| SE420720B (sv) | 1981-10-26 |
| DK579774A (en, 2012) | 1975-07-07 |
| FR2250521B1 (en, 2012) | 1979-03-16 |
| SE7414045L (en, 2012) | 1975-05-12 |
| DK138791B (da) | 1978-10-30 |
| FI324374A7 (en, 2012) | 1975-05-10 |
| FI62064B (fi) | 1982-07-30 |
| CA1032962A (en) | 1978-06-13 |
| CH616656A5 (en, 2012) | 1980-04-15 |
| GB1487852A (en) | 1977-10-05 |
| IE40409L (en) | 1975-05-09 |
| FI62064C (fi) | 1982-11-10 |
| JPS5077328A (en, 2012) | 1975-06-24 |
| DE2452691A1 (de) | 1975-05-15 |
| IE40409B1 (en) | 1979-05-23 |
| NL7315350A (nl) | 1975-05-13 |
| AR205358A1 (es) | 1976-04-30 |
| HU171856B (hu) | 1978-04-28 |
| FR2250521A1 (en, 2012) | 1975-06-06 |
| US3972932A (en) | 1976-08-03 |
| DK138791C (en, 2012) | 1979-04-09 |
| BE822019A (fr) | 1975-05-09 |
| JPS5546389B2 (en, 2012) | 1980-11-22 |
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