ES429698A2 - Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES429698A2
ES429698A2 ES429698A ES429698A ES429698A2 ES 429698 A2 ES429698 A2 ES 429698A2 ES 429698 A ES429698 A ES 429698A ES 429698 A ES429698 A ES 429698A ES 429698 A2 ES429698 A2 ES 429698A2
Authority
ES
Spain
Prior art keywords
denotes
formula
image
bencilamines
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES429698A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732345443 external-priority patent/DE2345443C3/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES429698A2 publication Critical patent/ES429698A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

2-Aminobenzylamines of the formula (I) < IMAGE > in which Hal denotes a bromine or chlorine atom R1 denotes a hydrogen or bromine atom R2 denotes a cyclohexyl, hydroxycyclohexyl or morpholinocarbonylmethyl radical and R3 denotes a hydrogen atom or a methyl group, are prepared in excellent yields with the aid of a novel process. This process starts from novel compounds of the formula (II) < IMAGE > in which R4 denotes a methyl or phenyl group, which are reacted with an amine of the formula (III) < IMAGE > The compounds of the formula (I) and their physiologically tolerable salts with inorganic or organic acids are distinguished by secretolytic and/or antitussive actions.
ES429698A 1973-09-08 1974-08-31 Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding) Expired ES429698A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732345443 DE2345443C3 (en) 1973-09-08 Process for the preparation of 2-amino-benzylamines

Publications (1)

Publication Number Publication Date
ES429698A2 true ES429698A2 (en) 1977-07-01

Family

ID=5892074

Family Applications (1)

Application Number Title Priority Date Filing Date
ES429698A Expired ES429698A2 (en) 1973-09-08 1974-08-31 Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding)

Country Status (14)

Country Link
JP (1) JPS594413B2 (en)
AT (1) AT327875B (en)
BG (1) BG23896A3 (en)
CA (1) CA1050542A (en)
CH (1) CH612662A5 (en)
CS (1) CS167212B2 (en)
DK (2) DK473074A (en)
ES (1) ES429698A2 (en)
FI (1) FI60551C (en)
HU (1) HU167685B (en)
NL (1) NL7410820A (en)
PL (1) PL91734B1 (en)
SE (2) SE439158B (en)
YU (1) YU37109B (en)

Also Published As

Publication number Publication date
SE439158B (en) 1985-06-03
ATA650974A (en) 1975-05-15
PL91734B1 (en) 1977-03-31
FI231774A (en) 1975-03-09
FI60551C (en) 1982-02-10
SE427178B (en) 1983-03-14
SE7709868L (en) 1977-09-01
BG23896A3 (en) 1977-11-10
SE7411313L (en) 1975-03-10
NL7410820A (en) 1975-03-11
JPS5053347A (en) 1975-05-12
CA1050542A (en) 1979-03-13
HU167685B (en) 1975-11-28
FI60551B (en) 1981-10-30
DK579676A (en) 1976-12-22
JPS594413B2 (en) 1984-01-30
YU239274A (en) 1983-04-27
AT327875B (en) 1976-02-25
CS167212B2 (en) 1976-04-29
DK473074A (en) 1975-05-05
YU37109B (en) 1984-08-31
DE2345443B2 (en) 1976-01-02
CH612662A5 (en) 1979-08-15
DE2345443A1 (en) 1975-03-27

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