ES424931A1 - Un procedimiento de preparacion de piroglutamato de argini-na. - Google Patents
Un procedimiento de preparacion de piroglutamato de argini-na.Info
- Publication number
- ES424931A1 ES424931A1 ES424931A ES424931A ES424931A1 ES 424931 A1 ES424931 A1 ES 424931A1 ES 424931 A ES424931 A ES 424931A ES 424931 A ES424931 A ES 424931A ES 424931 A1 ES424931 A1 ES 424931A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- arginine
- preparation
- pyroglutamate
- arginine pyroglutamate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- UYCAGRPOUWSBIQ-WOYAITHZSA-N [(1s)-1-carboxy-4-(diaminomethylideneamino)butyl]azanium;(2s)-5-oxopyrrolidine-2-carboxylate Chemical compound OC(=O)[C@@H]1CCC(=O)N1.OC(=O)[C@@H](N)CCCN=C(N)N UYCAGRPOUWSBIQ-WOYAITHZSA-N 0.000 title abstract 2
- 229940075863 arginine pyroglutamate Drugs 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- ODHCTXKNWHHXJC-GSVOUGTGSA-N Pyroglutamic acid Natural products OC(=O)[C@H]1CCC(=O)N1 ODHCTXKNWHHXJC-GSVOUGTGSA-N 0.000 abstract 1
- ODHCTXKNWHHXJC-UHFFFAOYSA-N acide pyroglutamique Natural products OC(=O)C1CCC(=O)N1 ODHCTXKNWHHXJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT49236/73A IT1019020B (it) | 1973-04-04 | 1973-04-04 | Arginia piroglutamato e procedi mento per prepararlo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES424931A1 true ES424931A1 (es) | 1976-05-16 |
Family
ID=11270040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES424931A Expired ES424931A1 (es) | 1973-04-04 | 1974-04-03 | Un procedimiento de preparacion de piroglutamato de argini-na. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5221572B2 (enrdf_load_stackoverflow) |
| AR (1) | AR203747A1 (enrdf_load_stackoverflow) |
| CH (1) | CH592058A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2416339C3 (enrdf_load_stackoverflow) |
| ES (1) | ES424931A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2224154B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1421089A (enrdf_load_stackoverflow) |
| IT (1) | IT1019020B (enrdf_load_stackoverflow) |
| ZA (1) | ZA742095B (enrdf_load_stackoverflow) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52102268U (enrdf_load_stackoverflow) * | 1976-01-30 | 1977-08-03 | ||
| IT1150694B (it) * | 1982-03-18 | 1986-12-17 | Baldacci Lab Spa | Composizione farmaceutica ad attivita' immunomodulatrice |
| JPS63143376U (enrdf_load_stackoverflow) * | 1987-03-10 | 1988-09-21 | ||
| IT1244548B (it) * | 1991-02-06 | 1994-07-15 | Poli Ind Chimica Spa | Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche |
| DE19520792A1 (de) * | 1995-06-07 | 1996-12-12 | Bloch Wilhelm Dr | Verwendung der Stickstoffmonoxidsynthese hemmenden Substanzen der Gruppe der L-Argininanaloge zur Herstellung eines Mittels zur Abschwellung entzündlich bzw. allergisch angeschwollener Nasenschleimhaut und der Hemmung entzündlich und allergisch bedingter Nasensekretion |
-
1973
- 1973-04-04 IT IT49236/73A patent/IT1019020B/it active
-
1974
- 1974-03-27 GB GB1352974A patent/GB1421089A/en not_active Expired
- 1974-04-02 AR AR253103A patent/AR203747A1/es active
- 1974-04-02 FR FR7411680A patent/FR2224154B1/fr not_active Expired
- 1974-04-02 ZA ZA00742095A patent/ZA742095B/xx unknown
- 1974-04-03 ES ES424931A patent/ES424931A1/es not_active Expired
- 1974-04-04 CH CH472574A patent/CH592058A5/xx not_active IP Right Cessation
- 1974-04-04 DE DE2416339A patent/DE2416339C3/de not_active Expired
- 1974-04-04 JP JP49038406A patent/JPS5221572B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2416339A1 (de) | 1975-02-13 |
| CH592058A5 (enrdf_load_stackoverflow) | 1977-10-14 |
| GB1421089A (en) | 1976-01-14 |
| AR203747A1 (es) | 1975-10-15 |
| ZA742095B (en) | 1975-04-30 |
| IT1019020B (it) | 1977-11-10 |
| FR2224154A1 (enrdf_load_stackoverflow) | 1974-10-31 |
| JPS5221572B2 (enrdf_load_stackoverflow) | 1977-06-11 |
| DE2416339C3 (de) | 1979-09-27 |
| FR2224154B1 (enrdf_load_stackoverflow) | 1977-11-04 |
| JPS5035317A (enrdf_load_stackoverflow) | 1975-04-04 |
| DE2416339B2 (de) | 1979-02-08 |
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