ES424717A1 - Procedimiento para preparar carboxamidas y tiocarboxamidas. - Google Patents
Procedimiento para preparar carboxamidas y tiocarboxamidas.Info
- Publication number
- ES424717A1 ES424717A1 ES424717A ES424717A ES424717A1 ES 424717 A1 ES424717 A1 ES 424717A1 ES 424717 A ES424717 A ES 424717A ES 424717 A ES424717 A ES 424717A ES 424717 A1 ES424717 A1 ES 424717A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- compound
- hydrogen
- group
- compound obtained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003857 carboxamides Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 27
- 150000001875 compounds Chemical class 0.000 abstract 24
- -1 4- (2, 1, 3-benzothiadiazolyl) -2-benzothiazolyl Chemical group 0.000 abstract 14
- 229910052739 hydrogen Inorganic materials 0.000 abstract 11
- 239000001257 hydrogen Substances 0.000 abstract 11
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 7
- 150000002431 hydrogen Chemical group 0.000 abstract 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 150000001447 alkali salts Chemical class 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 239000002168 alkylating agent Substances 0.000 abstract 2
- 229940100198 alkylating agent Drugs 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004530 1,2,4-triazinyl group Chemical group N1=NC(=NC=C1)* 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- BXDZOYLPNAIDOC-UHFFFAOYSA-N N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-1-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]piperidine-4-carboxamide Chemical compound CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCN(CC(=O)NCCOCCOCCOCCNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)CC3)s2)o1 BXDZOYLPNAIDOC-UHFFFAOYSA-N 0.000 abstract 1
- 238000005644 Wolff-Kishner reduction reaction Methods 0.000 abstract 1
- 125000000641 acridinyl group Chemical group C1(=CC=CC2=NC3=CC=CC=C3C=C12)* 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000000908 ammonium hydroxide Substances 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000005518 carboxamido group Chemical group 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000004966 cyanoalkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004307 pyrazin-2-yl group Chemical group [H]C1=C([H])N=C(*)C([H])=N1 0.000 abstract 1
- 125000002206 pyridazin-3-yl group Chemical group [H]C1=C([H])C([H])=C(*)N=N1 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
- 125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 abstract 1
- 125000004943 pyrimidin-6-yl group Chemical group N1=CN=CC=C1* 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US346005A US3928380A (en) | 1973-03-29 | 1973-03-29 | 1,1{40 -Spirobis(cyclopenta-{8 4,5-c{9 pyrroles) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES424717A1 true ES424717A1 (es) | 1976-11-01 |
Family
ID=23357526
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES424717A Expired ES424717A1 (es) | 1973-03-29 | 1974-03-28 | Procedimiento para preparar carboxamidas y tiocarboxamidas. |
| ES447116A Expired ES447116A1 (es) | 1973-03-29 | 1976-04-15 | Un procedimiento para preparar 2,4,5,6-tetrahidrociclopenta-(c)pirrol-4-carbonitrilos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES447116A Expired ES447116A1 (es) | 1973-03-29 | 1976-04-15 | Un procedimiento para preparar 2,4,5,6-tetrahidrociclopenta-(c)pirrol-4-carbonitrilos. |
Country Status (6)
| Country | Link |
|---|---|
| AR (1) | AR213064A1 (es) |
| ES (2) | ES424717A1 (es) |
| IE (1) | IE39694B1 (es) |
| IL (2) | IL44490A (es) |
| PH (1) | PH12366A (es) |
| SE (1) | SE7609982L (es) |
-
1974
- 1974-03-25 IL IL44490A patent/IL44490A/xx unknown
- 1974-03-26 IE IE656/74A patent/IE39694B1/xx unknown
- 1974-03-28 ES ES424717A patent/ES424717A1/es not_active Expired
- 1974-03-29 AR AR253065A patent/AR213064A1/es active
- 1974-03-29 PH PH7415680A patent/PH12366A/en unknown
-
1976
- 1976-04-15 ES ES447116A patent/ES447116A1/es not_active Expired
- 1976-08-11 IL IL50239A patent/IL50239A0/xx unknown
- 1976-09-09 SE SE7609982A patent/SE7609982L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12366A (en) | 1979-01-29 |
| IL44490A0 (en) | 1974-06-30 |
| SE7609982L (sv) | 1977-12-30 |
| AR213064A1 (es) | 1978-12-15 |
| IE39694L (en) | 1974-09-29 |
| IL50239A0 (en) | 1976-10-31 |
| IL44490A (en) | 1978-09-29 |
| IE39694B1 (en) | 1978-12-06 |
| ES447116A1 (es) | 1977-10-16 |
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