ES423972A1 - Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES423972A1 ES423972A1 ES423972A ES423972A ES423972A1 ES 423972 A1 ES423972 A1 ES 423972A1 ES 423972 A ES423972 A ES 423972A ES 423972 A ES423972 A ES 423972A ES 423972 A1 ES423972 A1 ES 423972A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- signifies
- radical
- general formula
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylpethyl radical, a branched alcohol radical with 3 to 5 carbon atoms substituted with 1 to 3 hydroxyl groups, the isopropyl, ter, butyl or terpentyl group, or a group of the formula **(See formula)** where R1 signifies a hydrogen atom, a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n signifies the numbers 0, 1 or 2 and the two radicals A and B signify hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means numbers 1 or 2, R4 represents a straight or branched chain alcohol radical with 1 to 4 carbon atoms, an alkenyl radical with 2 to 4 carbon atoms, or a cycloalkyl radical with 3 or 4 carbon atoms, if R3 does not represent any hydrogen atom or R2 represents a branched alcohol radical with 3 to 5 carbon atoms substituted with 1 to 3 groups hydroxyl, and l means the numbers 1 or 2, being a halogen atom in position 2, as well as its acid addition salts physiologically compatible with organic or inorganic acids, characterized in that a phenol of the general formula II is reacted, **(See formula)** wherein R1, Hal and l are as initially defined, one of the radicals Hal being in position 2 of the compound of the general formula VIII, with formaldehyde or paraformaldehyde and with an amine of the general formula III, **(See formula)** wherein R2 and R4 are as initially defined and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its salts physiologically compatible with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19722251891 DE2251891C3 (en) | 1972-10-23 | Benzylamines, their physiologically acceptable salts, processes for their preparation and pharmaceuticals containing them | |
DE19732320967 DE2320967C3 (en) | 1973-04-26 | New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them | |
DE2346743A DE2346743C3 (en) | 1972-10-23 | 1973-09-17 | 2- or 4-Hydroxy-3,5-dihalogenobenzylamines, their physiologically tolerable salts, processes for their preparation and medicaments containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ES423972A1 true ES423972A1 (en) | 1976-06-16 |
Family
ID=27184785
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES423969A Expired ES423969A1 (en) | 1972-10-23 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES74423971A Expired ES423971A1 (en) | 1972-10-23 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES423972A Expired ES423972A1 (en) | 1972-10-23 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES423969A Expired ES423969A1 (en) | 1972-10-23 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
ES74423971A Expired ES423971A1 (en) | 1972-10-23 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
Country | Link |
---|---|
AT (2) | ATA89375A (en) |
DE (1) | DE2346743C3 (en) |
ES (3) | ES423969A1 (en) |
MX (1) | MX3103E (en) |
PH (1) | PH13986A (en) |
PL (2) | PL96274B1 (en) |
SU (3) | SU517248A3 (en) |
-
1973
- 1973-09-17 DE DE2346743A patent/DE2346743C3/en not_active Expired
- 1973-10-17 AT AT89375*A patent/ATA89375A/en not_active IP Right Cessation
- 1973-10-17 AT AT89075*A patent/ATA89075A/en not_active IP Right Cessation
- 1973-10-22 PH PH15134A patent/PH13986A/en unknown
- 1973-10-22 PL PL1973176692A patent/PL96274B1/en unknown
- 1973-10-22 PL PL1973176689A patent/PL91886B1/en unknown
- 1973-10-23 MX MX003606U patent/MX3103E/en unknown
-
1974
- 1974-03-06 ES ES423969A patent/ES423969A1/en not_active Expired
- 1974-03-06 ES ES74423971A patent/ES423971A1/en not_active Expired
- 1974-03-06 ES ES423972A patent/ES423972A1/en not_active Expired
- 1974-10-10 SU SU2065436A patent/SU517248A3/en active
- 1974-10-10 SU SU2065408A patent/SU519123A3/en active
- 1974-10-10 SU SU2065438A patent/SU520033A3/en active
Also Published As
Publication number | Publication date |
---|---|
ATA89075A (en) | 1975-07-15 |
DE2346743C3 (en) | 1979-07-12 |
SU519123A3 (en) | 1976-06-25 |
ES423971A1 (en) | 1976-06-16 |
PL96274B1 (en) | 1977-12-31 |
DE2346743B2 (en) | 1978-11-09 |
ATA89375A (en) | 1975-07-15 |
PH13986A (en) | 1980-11-20 |
PL91886B1 (en) | 1977-03-31 |
SU520033A3 (en) | 1976-06-30 |
ES423969A1 (en) | 1976-06-16 |
DE2346743A1 (en) | 1975-04-03 |
MX3103E (en) | 1980-04-10 |
SU517248A3 (en) | 1976-06-05 |
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