ES423970A1 - Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES423970A1
ES423970A1 ES423970A ES423970A ES423970A1 ES 423970 A1 ES423970 A1 ES 423970A1 ES 423970 A ES423970 A ES 423970A ES 423970 A ES423970 A ES 423970A ES 423970 A1 ES423970 A1 ES 423970A1
Authority
ES
Spain
Prior art keywords
radical
signifies
carbon atoms
group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423970A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722251891 external-priority patent/DE2251891C3/en
Priority claimed from DE2316325A external-priority patent/DE2316325A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES423970A1 publication Critical patent/ES423970A1/en
Expired legal-status Critical Current

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Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where R3 signifies a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n signifies the numbers 0, 1 or 2 and the two radicals A and B signify hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means numbers 1 or 2, R4 a hydrogen atom and l means numbers 1 or 2, as well as their acid addition salts Physiologically compatible with organic or inorganic acids, characterized in that a compound of the general formula is reduced **(See formula)** or a compound of the general formula IIa **(See formula)** where R1, R2, Hal and l are as initially defined; Z signifies a cyclohexylidene radical optionally substituted with a hydroxy group or with an alcohol group with 1 to 4 carbon atoms, a branched alcoholicidene radical with 3 to 5 carbon atoms or the morpholinocarbonylmethylidene radical and R7 means a hydrogen atom or a radical of carboxylic acid; and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
ES423970A 1972-10-23 1974-03-16 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) Expired ES423970A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19722251891 DE2251891C3 (en) 1972-10-23 Benzylamines, their physiologically acceptable salts, processes for their preparation and pharmaceuticals containing them
DE2316325A DE2316325A1 (en) 1972-10-23 1973-04-02 Halo-hydroxy-substd-benzylamines - as secretolytic and antitussive agents
DE19732320967 DE2320967C3 (en) 1973-04-26 New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them

Publications (1)

Publication Number Publication Date
ES423970A1 true ES423970A1 (en) 1976-07-01

Family

ID=27184783

Family Applications (3)

Application Number Title Priority Date Filing Date
ES419607A Expired ES419607A1 (en) 1972-10-23 1973-10-13 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423970A Expired ES423970A1 (en) 1972-10-23 1974-03-16 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES432699A Expired ES432699A2 (en) 1972-10-23 1974-12-07 Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES419607A Expired ES419607A1 (en) 1972-10-23 1973-10-13 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES432699A Expired ES432699A2 (en) 1972-10-23 1974-12-07 Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (3) ES419607A1 (en)

Also Published As

Publication number Publication date
ES419607A1 (en) 1976-06-16
ES432699A2 (en) 1977-07-01

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