ES423780A1 - Production of 2,5-disubstituted benzamides - Google Patents

Production of 2,5-disubstituted benzamides

Info

Publication number
ES423780A1
ES423780A1 ES423780A ES423780A ES423780A1 ES 423780 A1 ES423780 A1 ES 423780A1 ES 423780 A ES423780 A ES 423780A ES 423780 A ES423780 A ES 423780A ES 423780 A1 ES423780 A1 ES 423780A1
Authority
ES
Spain
Prior art keywords
formula
radical
molecular weight
alcoholic
low molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423780A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES423780A1 publication Critical patent/ES423780A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of benzamides of the general formula: ** (See formula) ** as well as its addition salts with pharmaceutically acceptable organic or mineral acids and its quaternary ammonium salts, formula (I) in which A can be either a low molecular weight monoalkoxylamino or dialcoylamino radical in which the alcohol groups can be united together to form a ring with or without nitrogen, oxygen or sulfur, and when the ring contains a nitrogen atom, the nitrogen atom may be attached to a low molecular weight alcohol group, the rings being thus formed for example: pyrrolidinyl, piperidinyl, imidazolidinyl, piperazine, morpholino, thiazolidinyl, or A can be a heterocyclic radical of the form: ** (See formula) ** R being a low molecular weight alcoholic radical, or alcoholic; m is an integer less than 4; and B can be a low molecular weight alcohol radical or an alcohol radical; n = 1 or 2; and X can be an amino, monoalkoxylamino or dialcohilamino, alcoholic or alcoholic radical; said procedure consisting of starting a benzoic acid disubstituted in positions 2 and 5 of the formula: ** (See formula) ** where B and X have the same meanings as described above, and in treating it with an amine of the formula: H2N (CH2) nA (III) where A has the same meaning as described above, in the presence of silicon tetrachloride, so that the desired benzamide of formula (I) is obtained. (Machine-translation by Google Translate, not legally binding)
ES423780A 1973-03-05 1974-03-01 Production of 2,5-disubstituted benzamides Expired ES423780A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7307840A FR2220519B1 (en) 1973-03-05 1973-03-05

Publications (1)

Publication Number Publication Date
ES423780A1 true ES423780A1 (en) 1977-01-16

Family

ID=9115815

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423780A Expired ES423780A1 (en) 1973-03-05 1974-03-01 Production of 2,5-disubstituted benzamides

Country Status (9)

Country Link
JP (1) JPS5716983B2 (en)
AR (1) AR201943A1 (en)
AT (1) AT331220B (en)
CA (1) CA1015365A (en)
DE (1) DE2409892A1 (en)
ES (1) ES423780A1 (en)
FR (1) FR2220519B1 (en)
GB (1) GB1420912A (en)
IE (1) IE38948B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305176A1 (en) * 1975-03-28 1976-10-22 Ile De France NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE

Also Published As

Publication number Publication date
JPS5716983B2 (en) 1982-04-08
ATA158874A (en) 1975-11-15
DE2409892A1 (en) 1974-09-12
JPS49117448A (en) 1974-11-09
IE38948L (en) 1974-09-05
IE38948B1 (en) 1978-07-05
AR201943A1 (en) 1975-04-30
GB1420912A (en) 1976-01-14
CA1015365A (en) 1977-08-09
FR2220519A1 (en) 1974-10-04
FR2220519B1 (en) 1978-02-10
AT331220B (en) 1976-08-10

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