ES423629A1 - Preparation of 2,5-disubsituted benzamides - Google Patents
Preparation of 2,5-disubsituted benzamidesInfo
- Publication number
- ES423629A1 ES423629A1 ES423629A ES423629A ES423629A1 ES 423629 A1 ES423629 A1 ES 423629A1 ES 423629 A ES423629 A ES 423629A ES 423629 A ES423629 A ES 423629A ES 423629 A1 ES423629 A1 ES 423629A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- radical
- molecular weight
- alcoholic
- low molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
Procedure for the preparation of benzamides of the general formula: **(See formula)** as well as their addition salts with pharmaceutically acceptable mineral or organic acids and their quaternary ammonium salts; in which formula (I): A can be either a low molecular weight mono- or dialkoxylamino radical in which the alcohol groups can be linked together to form a ring with or without nitrogen, oxygen or sulfur; when the ring contains a nitrogen atom, the nitrogen atom may be attached to a low molecular weight alcohol group, the rings being thus formed for example: pyrrolidinyl, piperidinyl, imidazolidinyl, piperazine, morpholino thiazolidinyl, or A is a radical heterocyclic of the form: **(See formula)** R being a low molecular weight alcoholic radical, or alcoholic; m an integer of less than 4, B can be a low molecular weight alcohol radical or an alcohol radical; n = 1 or 2; X can be an amino, mono- or dialcoylamino, alcoholic or alcoholic radical; said procedure consisting of a benzoyl chloride disubstituted in positions 2 and 5, of the formula: **(See formula)** where B and X have the same meanings as above and treat it with lead sulfocyanide, so that the corresponding benzoyl isothiocyanate is obtained, then reacting this benzoyl isothiocyanate with an amine of the formula: H2N (CH2) nA (III) where A has the same value as above, so that the desired benzamide of formula (I) is obtained. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7307434A FR2219941B1 (en) | 1973-03-01 | 1973-03-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES423629A1 true ES423629A1 (en) | 1976-06-16 |
Family
ID=9115666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES423629A Expired ES423629A1 (en) | 1973-03-01 | 1974-02-26 | Preparation of 2,5-disubsituted benzamides |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5720946B2 (en) |
AR (1) | AR202294A1 (en) |
AT (1) | AT331223B (en) |
CA (1) | CA1015367A (en) |
DE (1) | DE2409386A1 (en) |
ES (1) | ES423629A1 (en) |
FR (1) | FR2219941B1 (en) |
GB (1) | GB1420574A (en) |
IE (1) | IE38929B1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2305176A1 (en) * | 1975-03-28 | 1976-10-22 | Ile De France | NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE |
-
1973
- 1973-03-01 FR FR7307434A patent/FR2219941B1/fr not_active Expired
-
1974
- 1974-02-25 CA CA193,454A patent/CA1015367A/en not_active Expired
- 1974-02-26 IE IE39074A patent/IE38929B1/en unknown
- 1974-02-26 ES ES423629A patent/ES423629A1/en not_active Expired
- 1974-02-26 GB GB866574A patent/GB1420574A/en not_active Expired
- 1974-02-27 AR AR25252274A patent/AR202294A1/en active
- 1974-02-27 AT AT159274A patent/AT331223B/en not_active IP Right Cessation
- 1974-02-27 DE DE19742409386 patent/DE2409386A1/en active Pending
- 1974-02-27 JP JP2323374A patent/JPS5720946B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IE38929B1 (en) | 1978-07-05 |
IE38929L (en) | 1974-09-01 |
JPS5720946B2 (en) | 1982-05-04 |
AT331223B (en) | 1976-08-10 |
AR202294A1 (en) | 1975-05-30 |
ATA159274A (en) | 1975-11-15 |
GB1420574A (en) | 1976-01-07 |
CA1015367A (en) | 1977-08-09 |
JPS49134652A (en) | 1974-12-25 |
FR2219941A1 (en) | 1974-09-27 |
FR2219941B1 (en) | 1977-02-04 |
DE2409386A1 (en) | 1974-09-05 |
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