ES418328A1 - Un procedimiento para la preparacion de nuevos derivados deacido 1-acilanidocefalosporanico 3-tiolado. - Google Patents

Un procedimiento para la preparacion de nuevos derivados deacido 1-acilanidocefalosporanico 3-tiolado.

Info

Publication number
ES418328A1
ES418328A1 ES418328A ES418328A ES418328A1 ES 418328 A1 ES418328 A1 ES 418328A1 ES 418328 A ES418328 A ES 418328A ES 418328 A ES418328 A ES 418328A ES 418328 A1 ES418328 A1 ES 418328A1
Authority
ES
Spain
Prior art keywords
formula
easily hydrolyzable
ester
preparation
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES418328A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00285764A external-priority patent/US3813376A/en
Priority claimed from US00286792A external-priority patent/US3823141A/en
Priority claimed from US00286630A external-priority patent/US3813390A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES418328A1 publication Critical patent/ES418328A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/67Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES418328A 1972-08-31 1973-08-30 Un procedimiento para la preparacion de nuevos derivados deacido 1-acilanidocefalosporanico 3-tiolado. Expired ES418328A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US00285764A US3813376A (en) 1972-08-31 1972-08-31 7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US00286792A US3823141A (en) 1972-09-06 1972-09-06 7-(o-aminomethyl-p-hydroxy-phenylacetamido)-3-(3-hydroxy-pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US00286630A US3813390A (en) 1972-09-06 1972-09-06 7-(o-aminomethylphenylthioacetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
ES418328A1 true ES418328A1 (es) 1976-09-01

Family

ID=27403558

Family Applications (1)

Application Number Title Priority Date Filing Date
ES418328A Expired ES418328A1 (es) 1972-08-31 1973-08-30 Un procedimiento para la preparacion de nuevos derivados deacido 1-acilanidocefalosporanico 3-tiolado.

Country Status (10)

Country Link
JP (1) JPS5930716B2 (es)
AU (1) AU476592B2 (es)
DE (1) DE2344095A1 (es)
DK (1) DK145465C (es)
ES (1) ES418328A1 (es)
FI (1) FI57420C (es)
FR (1) FR2279408A1 (es)
GB (1) GB1412721A (es)
NL (1) NL7312062A (es)
SE (1) SE415980B (es)

Also Published As

Publication number Publication date
AU476592B2 (en) 1976-09-30
FI57420C (fi) 1980-08-11
SE415980B (sv) 1980-11-17
DE2344095A1 (de) 1974-04-18
GB1412721A (en) 1975-11-05
FR2279408A1 (fr) 1976-02-20
NL7312062A (es) 1974-03-04
JPS5930716B2 (ja) 1984-07-28
AU5974273A (en) 1975-03-06
JPS4992091A (es) 1974-09-03
FI57420B (fi) 1980-04-30
DK145465C (da) 1983-04-18
FR2279408B1 (es) 1978-07-28
DK145465B (da) 1982-11-22

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