ES417147A1 - Procedimiento para la preparacion de lactona de acido beta-(3-ceto-7 alfa-acetiltio-17 beta-hidroxi-4-androsten-17 al- fa-il)-propionico. - Google Patents
Procedimiento para la preparacion de lactona de acido beta-(3-ceto-7 alfa-acetiltio-17 beta-hidroxi-4-androsten-17 al- fa-il)-propionico.Info
- Publication number
- ES417147A1 ES417147A1 ES417147A ES417147A ES417147A1 ES 417147 A1 ES417147 A1 ES 417147A1 ES 417147 A ES417147 A ES 417147A ES 417147 A ES417147 A ES 417147A ES 417147 A1 ES417147 A1 ES 417147A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- signifies
- see formula
- hydroxy
- signify
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 4
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- -1 acetylthio Chemical group 0.000 abstract 1
- 239000003929 acidic solution Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 125000000457 gamma-lactone group Chemical group 0.000 abstract 1
- 125000001976 hemiacetal group Chemical group 0.000 abstract 1
- 150000002373 hemiacetals Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- KOUKXHPPRFNWPP-UHFFFAOYSA-N pyrazine-2,5-dicarboxylic acid;hydrate Chemical compound O.OC(=O)C1=CN=C(C(O)=O)C=N1 KOUKXHPPRFNWPP-UHFFFAOYSA-N 0.000 abstract 1
- 238000003797 solvolysis reaction Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2237143A DE2237143A1 (de) | 1972-07-28 | 1972-07-28 | Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES417147A1 true ES417147A1 (es) | 1976-03-01 |
Family
ID=5852010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417147A Expired ES417147A1 (es) | 1972-07-28 | 1973-07-21 | Procedimiento para la preparacion de lactona de acido beta-(3-ceto-7 alfa-acetiltio-17 beta-hidroxi-4-androsten-17 al- fa-il)-propionico. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3900467A (fi) |
| JP (1) | JPS4943962A (fi) |
| AT (1) | AT340609B (fi) |
| AU (1) | AU474287B2 (fi) |
| BE (1) | BE802974A (fi) |
| CA (1) | CA1019722A (fi) |
| CH (1) | CH593997A5 (fi) |
| DE (1) | DE2237143A1 (fi) |
| DK (1) | DK131574C (fi) |
| ES (1) | ES417147A1 (fi) |
| FI (1) | FI50985C (fi) |
| FR (1) | FR2198937B1 (fi) |
| GB (1) | GB1444272A (fi) |
| NL (1) | NL7310227A (fi) |
| SE (1) | SE383155B (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3972871A (en) * | 1975-09-22 | 1976-08-03 | G. D. Searle & Co. | 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners |
| DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| YU41412B (en) * | 1978-08-15 | 1987-04-30 | Gist Brocades Nv | Process for obtaining 17 beta-hydroxy -3-dxo-17 alpha-pregn-4-en-21-carboxylic acid |
| DE3227598A1 (de) * | 1982-07-22 | 1984-01-26 | Schering AG, 1000 Berlin und 4709 Bergkamen | 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| US4501695A (en) * | 1983-05-16 | 1985-02-26 | The Upjohn Company | Spironalactone process |
| US5319115A (en) * | 1987-08-25 | 1994-06-07 | Cocensys Inc. | Method for making 3α-hydroxy, 3β-substituted-pregnanes |
| GB0711948D0 (en) * | 2007-06-20 | 2007-08-01 | Bionature E A Ltd | Neurosteriod compounds |
| JP6833832B2 (ja) | 2015-09-30 | 2021-02-24 | コーニング インコーポレイテッド | マイクロ波透過領域を有するマイクロ波モードスターラ装置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3137690A (en) * | 1963-09-26 | 1964-06-16 | Searle & Co | 17beta-hydroxy-3-oxoandrost-4-en-17alpha-ylpropionaldehyde lactol and delta1, delta6, delta1, 6, 19-nor and 7alpha-acetylthio congeners |
-
1972
- 1972-07-28 DE DE2237143A patent/DE2237143A1/de active Pending
-
1973
- 1973-07-21 ES ES417147A patent/ES417147A1/es not_active Expired
- 1973-07-23 NL NL7310227A patent/NL7310227A/xx not_active Application Discontinuation
- 1973-07-25 CH CH1087073A patent/CH593997A5/xx not_active IP Right Cessation
- 1973-07-26 US US382661A patent/US3900467A/en not_active Expired - Lifetime
- 1973-07-26 SE SE7310379A patent/SE383155B/xx unknown
- 1973-07-26 FR FR7327414A patent/FR2198937B1/fr not_active Expired
- 1973-07-26 FI FI732360A patent/FI50985C/fi active
- 1973-07-26 AU AU58527/73A patent/AU474287B2/en not_active Expired
- 1973-07-26 AT AT658873A patent/AT340609B/de not_active IP Right Cessation
- 1973-07-27 DK DK415973*A patent/DK131574C/da active
- 1973-07-27 GB GB3577973A patent/GB1444272A/en not_active Expired
- 1973-07-27 CA CA177,838A patent/CA1019722A/en not_active Expired
- 1973-07-28 JP JP48085369A patent/JPS4943962A/ja active Pending
- 1973-07-30 BE BE134021A patent/BE802974A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2237143A1 (de) | 1974-02-14 |
| SE7310379L (fi) | 1974-01-29 |
| AU5852773A (en) | 1975-01-30 |
| FR2198937A1 (fi) | 1974-04-05 |
| FR2198937B1 (fi) | 1976-09-17 |
| DK131574C (da) | 1976-01-05 |
| DK131574B (da) | 1975-08-04 |
| FI50985B (fi) | 1976-05-31 |
| US3900467A (en) | 1975-08-19 |
| JPS4943962A (fi) | 1974-04-25 |
| BE802974A (fr) | 1974-01-30 |
| AU474287B2 (en) | 1976-07-15 |
| GB1444272A (en) | 1976-07-28 |
| AT340609B (de) | 1977-12-27 |
| SE383155B (sv) | 1976-03-01 |
| FI50985C (fi) | 1976-09-10 |
| CH593997A5 (fi) | 1977-12-30 |
| ATA658873A (de) | 1977-04-15 |
| CA1019722A (en) | 1977-10-25 |
| NL7310227A (fi) | 1974-01-30 |
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