ES417073A1 - Procedure for the preparation of active triciclic compounds, as shock absorbers of the central nervous system and neurolopticos. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of active triciclic compounds, as shock absorbers of the central nervous system and neurolopticos. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES417073A1 ES417073A1 ES417073A ES417073A ES417073A1 ES 417073 A1 ES417073 A1 ES 417073A1 ES 417073 A ES417073 A ES 417073A ES 417073 A ES417073 A ES 417073A ES 417073 A1 ES417073 A1 ES 417073A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- indicated
- general formula
- hydrogenated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedure for the preparation of tricyclic compounds active as central nervous system and neuroleptic buffers of the general formula **(See formula)** in which n represents the number 2, 3 or 4, R1 represents a halogen atom or a group of lower alkyl, di (lower alkyl) sulfamoyl, nitro, amino, di (lower alkyl) amino or trifluoromethyl, X represents an oxygen atom or an imino group, (lower alkyl) imino or methylene, m represents the number 0 or 1 and R2 and R3 each represent a hydrogen atom, or R2 and R3 represent the grouping **(See formula)** and where the link indicated by a broken line may be hydrogenated, and its salts, whose process includes (a) reacting a compound of the general formula **(See formula)** in which R1 has the meaning indicated above and Y represents a part atom with a compound of the general formula **(See formula)** in which m, n, R2, R3 and X have the meaning indicated above, to obtain a compound of formula I in which the bond indicated by a broken line is hydrogenated, or, in an alternative thereof, (b) reducing a compound of the general formula **(See formula)** in which m, n, R1, R2, R3 and X have the meaning indicated above, to obtain a compound of formula I where the indicated bond with a broken line is hydrogenated, or, in a variant thereof, (c) reacting a compound of the general formula **(See formula)** in which R1 has the meaning indicated above, with a compound of the general formula **(See formula)** in which m, n, X, R2 and R3 have the meaning indicated above, and Y has the meaning set forth above in this claim, to obtain a compound of formula I where the indicated bond with a broken line is hydrogenated, or in another alternative (d) reacting a compound of the general formula **(See formula)** in which R1 has the meaning indicated above, with a compound of formula III, set forth above in this claim, to obtain a compound of formula I wherein the bond indicated by a broken line is not hydrogenated and, in any case, if desired, reduce an indicated nitro group by R1 to obtain the amino group; proceed, if desired, to the di (lower alkylation) of an amino group indicated by and, convert, if desired, a compound of formula I obtained into a salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1100172A CH569013A5 (en) | 1972-07-21 | 1972-07-21 | |
| CH705973 | 1973-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES417073A1 true ES417073A1 (en) | 1976-05-16 |
Family
ID=25700663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417073A Expired ES417073A1 (en) | 1972-07-21 | 1973-07-20 | Procedure for the preparation of active triciclic compounds, as shock absorbers of the central nervous system and neurolopticos. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES417073A1 (en) |
-
1973
- 1973-07-20 ES ES417073A patent/ES417073A1/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES408565A1 (en) | Cyclic diamine derivatives | |
| ES387016A1 (en) | Isoquinoline derivatives | |
| GB925429A (en) | Indole derivatives | |
| ES420179A1 (en) | Tricyclic imines | |
| ES422906A1 (en) | Derivatives of 2-aminoindane, the preparation and use thereof | |
| ES417073A1 (en) | Procedure for the preparation of active triciclic compounds, as shock absorbers of the central nervous system and neurolopticos. (Machine-translation by Google Translate, not legally binding) | |
| ES390163A1 (en) | Procedure for the preparation of amino-derivatives of pirazolo (3,4-b) pyridine-5-carboxylic acids. (Machine-translation by Google Translate, not legally binding) | |
| ES394761A1 (en) | 2-amino-1,5-benzodiazocine derivatives | |
| ES433299A1 (en) | Procedure for the preparation of new benzopiran derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES419386A1 (en) | Indenopyrrole derivatives | |
| ES362612A1 (en) | 3-hydrocarbon-4-tertiary amino methyl sydnones | |
| GB1226251A (en) | ||
| GB1065889A (en) | Improvements in or relating to the production of isoxazole compounds and the products thereof | |
| ES416231A1 (en) | Procedure for preparation of a heterocicles nenzamide compound. (Machine-translation by Google Translate, not legally binding) | |
| ES372424A1 (en) | A procedure to prepare a feed composition for birds. (Machine-translation by Google Translate, not legally binding) | |
| GB1042205A (en) | Manufacture of benzo[a]quinolizines | |
| ES419548A1 (en) | N-(indazolyl-n1-methyl)dialkanolamines | |
| ES422085A1 (en) | Primary amino acylanilides methods of making the same and use as antiarrhythmic drugs | |
| ES387921A1 (en) | A procedure for the preparation of derivatives of difeniltetrafluoretano. (Machine-translation by Google Translate, not legally binding) | |
| GB1159223A (en) | Novel N-Substituted Azabicyclooctanes and -Nonanes and the preparation thereof | |
| GB1308181A (en) | 5-nitrofur furylidenalkyl derivatives processes for their manufactur and their use as feedstuff additives | |
| ES382297A1 (en) | 0,4-methano and 1,4-ethano-tetrahydronaphthyloxypropanols | |
| ES243575A1 (en) | Procedure for preparing compounds of 1,1-dioxide of 3-oxo-3,4-dihydro-1,2,4-benzotiadiacin (Machine-translation by Google Translate, not legally binding) | |
| GB1293909A (en) | Halopyridine derivatives | |
| ES443599A1 (en) | A procedure for the preparation of 3-alkyl-3-cefem-4-carboxylic acids. (Machine-translation by Google Translate, not legally binding) |