ES416110A1 - Un procedimiento para preparar compuestos de cefalospori- nas. - Google Patents
Un procedimiento para preparar compuestos de cefalospori- nas.Info
- Publication number
- ES416110A1 ES416110A1 ES416110A ES416110A ES416110A1 ES 416110 A1 ES416110 A1 ES 416110A1 ES 416110 A ES416110 A ES 416110A ES 416110 A ES416110 A ES 416110A ES 416110 A1 ES416110 A1 ES 416110A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- carbon atoms
- group
- alkoxy
- heterocyclic ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 125000001951 carbamoylamino group Chemical class C(N)(=O)N* 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- -1 methoxy, azido, amino, carboxyl Chemical group 0.000 abstract 7
- 125000003545 alkoxy group Chemical group 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 3
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 3
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 239000000376 reactant Substances 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- HQWDILUMZXPFNW-UHFFFAOYSA-N 2-cyano-2-nitroacetamide Chemical group NC(=O)C(C#N)[N+]([O-])=O HQWDILUMZXPFNW-UHFFFAOYSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940056218 acid gone Drugs 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- NONOKGVFTBWRLD-UHFFFAOYSA-N isocyanatosulfanylimino(oxo)methane Chemical compound O=C=NSN=C=O NONOKGVFTBWRLD-UHFFFAOYSA-N 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26537172A | 1972-06-22 | 1972-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES416110A1 true ES416110A1 (es) | 1976-02-16 |
Family
ID=23010158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES416110A Expired ES416110A1 (es) | 1972-06-22 | 1973-06-20 | Un procedimiento para preparar compuestos de cefalospori- nas. |
Country Status (10)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4164586A (en) * | 1974-07-19 | 1979-08-14 | Hoffmann-La Roche Inc. | Therapeutic agent for improving cardiovascular function |
| US4174399A (en) * | 1978-07-10 | 1979-11-13 | Syntex (Usa) Inc. | Treatment of lactic acidosis in ruminants |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792112A (fr) * | 1971-12-06 | 1973-05-30 | Smith Kline French Lab | 7-ureidocephalosporines |
-
1973
- 1973-05-29 ZA ZA733650A patent/ZA733650B/xx unknown
- 1973-06-14 CH CH865373A patent/CH573945A5/xx not_active IP Right Cessation
- 1973-06-19 BE BE132416A patent/BE801099A/xx unknown
- 1973-06-20 ES ES416110A patent/ES416110A1/es not_active Expired
- 1973-06-20 FR FR7322462A patent/FR2189018B1/fr not_active Expired
- 1973-06-20 DE DE2331599A patent/DE2331599A1/de active Pending
- 1973-06-20 LU LU67826A patent/LU67826A1/xx unknown
- 1973-06-21 NL NL7308634A patent/NL7308634A/xx unknown
- 1973-06-22 JP JP48071235A patent/JPS4954394A/ja active Pending
- 1973-06-22 GB GB2969973A patent/GB1392156A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE801099A (fr) | 1973-12-19 |
| CH573945A5 (enrdf_load_stackoverflow) | 1976-03-31 |
| GB1392156A (en) | 1975-04-30 |
| DE2331599A1 (de) | 1974-01-10 |
| FR2189018B1 (enrdf_load_stackoverflow) | 1976-12-31 |
| FR2189018A1 (enrdf_load_stackoverflow) | 1974-01-25 |
| JPS4954394A (enrdf_load_stackoverflow) | 1974-05-27 |
| AU5726073A (en) | 1975-01-09 |
| NL7308634A (enrdf_load_stackoverflow) | 1973-12-27 |
| LU67826A1 (enrdf_load_stackoverflow) | 1973-08-28 |
| ZA733650B (en) | 1974-04-24 |
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