ES412468A1 - Un procedimiento para la produccion de acido 7-aminocefa- losporanico. - Google Patents
Un procedimiento para la produccion de acido 7-aminocefa- losporanico.Info
- Publication number
- ES412468A1 ES412468A1 ES412468A ES412468A ES412468A1 ES 412468 A1 ES412468 A1 ES 412468A1 ES 412468 A ES412468 A ES 412468A ES 412468 A ES412468 A ES 412468A ES 412468 A1 ES412468 A1 ES 412468A1
- Authority
- ES
- Spain
- Prior art keywords
- chloride
- cephalosporin
- imino
- acid
- cephalosporin derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 150000001780 cephalosporins Chemical class 0.000 title abstract 2
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 4
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 3
- 235000010633 broth Nutrition 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 2
- 230000004151 fermentation Effects 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- IPIVAXLHTVNRBS-UHFFFAOYSA-N decanoyl chloride Chemical compound CCCCCCCCCC(Cl)=O IPIVAXLHTVNRBS-UHFFFAOYSA-N 0.000 abstract 1
- WASQWSOJHCZDFK-UHFFFAOYSA-N diketene Chemical compound C=C1CC(=O)O1 WASQWSOJHCZDFK-UHFFFAOYSA-N 0.000 abstract 1
- NQGIJDNPUZEBRU-UHFFFAOYSA-N dodecanoyl chloride Chemical compound CCCCCCCCCCCC(Cl)=O NQGIJDNPUZEBRU-UHFFFAOYSA-N 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- -1 silyl di-ester Chemical class 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1100672A GB1395184A (en) | 1972-03-09 | 1972-03-09 | Cephalosporin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES412468A1 true ES412468A1 (es) | 1976-05-01 |
Family
ID=9978321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES412468A Expired ES412468A1 (es) | 1972-03-09 | 1973-03-08 | Un procedimiento para la produccion de acido 7-aminocefa- losporanico. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3931161A (en, 2012) |
| JP (1) | JPS49284A (en, 2012) |
| AR (1) | AR201427A1 (en, 2012) |
| AT (1) | AT331390B (en, 2012) |
| BE (1) | BE796540A (en, 2012) |
| CH (1) | CH580105A5 (en, 2012) |
| DE (1) | DE2311117A1 (en, 2012) |
| ES (1) | ES412468A1 (en, 2012) |
| FR (1) | FR2175204A1 (en, 2012) |
| GB (1) | GB1395184A (en, 2012) |
| HU (1) | HU168580B (en, 2012) |
| NL (1) | NL7303391A (en, 2012) |
| SU (1) | SU499812A3 (en, 2012) |
| ZA (1) | ZA731618B (en, 2012) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4916006A (en, 2012) * | 1972-06-07 | 1974-02-13 | ||
| JPS557438B2 (en, 2012) * | 1974-02-22 | 1980-02-25 | ||
| DE2619243C2 (de) * | 1975-05-06 | 1985-07-04 | Takeda Chemical Industries, Ltd., Osaka | Verfahren zur Herstellung von 3-Acyloxymethyl-cephem-Verbindungen |
| GR70261B (en, 2012) * | 1977-12-12 | 1982-09-02 | Takeda Chemical Industries Ltd | |
| WO1994012504A1 (en) * | 1992-12-02 | 1994-06-09 | Fujisawa Pharmaceutical Co., Ltd. | Method of purifying 7-aminocephalosporanic acid |
| RU2240388C1 (ru) * | 2003-11-25 | 2004-11-20 | Смирнова Елена Леонидовна | Термостойкий тканый материал |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3575970A (en) * | 1967-08-07 | 1971-04-20 | Koninklijke Gist Spiritus | Process for preparation of 7-amino-cephalosporanic acid compounds |
| US3573295A (en) * | 1968-07-01 | 1971-03-30 | Bristol Myers Co | Process for the preparation of 7-aminocephalosporanic acid |
| US3573296A (en) * | 1968-07-01 | 1971-03-30 | Bristol Myers Co | Process for the preparation of 7-aminocephalosporanic acid |
| US3641018A (en) * | 1969-06-26 | 1972-02-08 | Lilly Co Eli | Process for preparing 7-amino cephalosporanic acid |
| GB1355347A (en) * | 1970-08-25 | 1974-06-05 | Glaxo Lab Ltd | Recovery of cephalosporin c and derivatives thereof |
| BE788142A (fr) * | 1971-09-03 | 1973-02-28 | Lilly Co Eli | Procede de preparation de l'acide 7-aminocephalosporanique |
-
1972
- 1972-03-09 GB GB1100672A patent/GB1395184A/en not_active Expired
-
1973
- 1973-03-06 HU HUAA726A patent/HU168580B/hu unknown
- 1973-03-06 US US05/338,515 patent/US3931161A/en not_active Expired - Lifetime
- 1973-03-07 SU SU1892343A patent/SU499812A3/ru active
- 1973-03-07 DE DE19732311117 patent/DE2311117A1/de active Pending
- 1973-03-08 ZA ZA731618A patent/ZA731618B/xx unknown
- 1973-03-08 ES ES412468A patent/ES412468A1/es not_active Expired
- 1973-03-08 CH CH342573A patent/CH580105A5/xx not_active IP Right Cessation
- 1973-03-08 AR AR246957A patent/AR201427A1/es active
- 1973-03-09 FR FR7308439A patent/FR2175204A1/fr not_active Withdrawn
- 1973-03-09 JP JP48027910A patent/JPS49284A/ja active Pending
- 1973-03-09 AT AT211973A patent/AT331390B/de not_active IP Right Cessation
- 1973-03-09 NL NL7303391A patent/NL7303391A/xx not_active Application Discontinuation
- 1973-03-09 BE BE128595A patent/BE796540A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT331390B (de) | 1976-08-25 |
| BE796540A (fr) | 1973-07-02 |
| ATA211973A (de) | 1975-11-15 |
| CH580105A5 (en, 2012) | 1976-09-30 |
| SU499812A3 (ru) | 1976-01-15 |
| DE2311117A1 (de) | 1973-09-20 |
| ZA731618B (en) | 1973-12-19 |
| NL7303391A (en, 2012) | 1973-09-11 |
| FR2175204A1 (en, 2012) | 1973-10-19 |
| US3931161A (en) | 1976-01-06 |
| HU168580B (en, 2012) | 1976-06-28 |
| JPS49284A (en, 2012) | 1974-01-05 |
| AR201427A1 (es) | 1975-03-14 |
| GB1395184A (en) | 1975-05-21 |
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