ES406374A1 - Procedimiento para la obtencion de 1-(3-trifluor - metil - fenil)-4-(ciclicas-amido-alquilicas)-piperazinas. - Google Patents
Procedimiento para la obtencion de 1-(3-trifluor - metil - fenil)-4-(ciclicas-amido-alquilicas)-piperazinas.Info
- Publication number
- ES406374A1 ES406374A1 ES406374A ES406374A ES406374A1 ES 406374 A1 ES406374 A1 ES 406374A1 ES 406374 A ES406374 A ES 406374A ES 406374 A ES406374 A ES 406374A ES 406374 A1 ES406374 A1 ES 406374A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- cyclic
- phenyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- VANNPISTIUFMLH-UHFFFAOYSA-N glutaric anhydride Chemical compound O=C1CCCC(=O)O1 VANNPISTIUFMLH-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000005424 tosyloxy group Chemical group S(=O)(=O)(C1=CC=C(C)C=C1)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4132271 | 1971-09-04 | ||
| GB2053672A GB1368256A (en) | 1971-09-04 | 1972-05-03 | 1- trifluoromethyl-phenyl- 4-cyclic-amidoalkyl- piperazines useful as amorectic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES406374A1 true ES406374A1 (es) | 1975-07-16 |
Family
ID=26254732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES406374A Expired ES406374A1 (es) | 1971-09-04 | 1972-09-04 | Procedimiento para la obtencion de 1-(3-trifluor - metil - fenil)-4-(ciclicas-amido-alquilicas)-piperazinas. |
Country Status (12)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
| DE2727469A1 (de) * | 1977-06-18 | 1978-12-21 | Hoechst Ag | Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
| NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
| NL8005131A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met analgetische werking. |
| US4452798A (en) * | 1982-06-22 | 1984-06-05 | Warner-Lambert Company | 1-Substituted phenyl-4-alkyl hydantoin piperazine compounds as antihypertensive agents |
| JPS5976059A (ja) * | 1982-10-21 | 1984-04-28 | Sumitomo Chem Co Ltd | 環状イミド誘導体及びその酸付加塩 |
| US6083950A (en) * | 1997-11-13 | 2000-07-04 | Ranbaxy Laboratories Limited | 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers |
| AU1979799A (en) * | 1998-07-21 | 2000-02-14 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uro-selective alpha-1-adrenoceptor blockers |
| WO2000005205A1 (en) * | 1998-07-21 | 2000-02-03 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers |
| US20050228180A1 (en) * | 2002-04-08 | 2005-10-13 | Mohammad Salman | Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers |
-
0
- BE BE788280D patent/BE788280A/xx unknown
-
1972
- 1972-05-03 GB GB2053672A patent/GB1368256A/en not_active Expired
- 1972-08-24 AU AU45940/72A patent/AU4594072A/en not_active Expired
- 1972-08-28 NL NL7211694A patent/NL7211694A/xx unknown
- 1972-08-29 IE IE117372A patent/IE37697B1/xx unknown
- 1972-08-29 DE DE19722242382 patent/DE2242382A1/de active Pending
- 1972-09-01 AT AT1089573A patent/AT320655B/de not_active IP Right Cessation
- 1972-09-01 AT AT752072A patent/AT321307B/de not_active IP Right Cessation
- 1972-09-01 CH CH356874A patent/CH551430A/fr not_active IP Right Cessation
- 1972-09-01 FR FR7231080A patent/FR2154449A1/fr not_active Withdrawn
- 1972-09-01 CH CH1293572A patent/CH554899A/fr not_active IP Right Cessation
- 1972-09-01 AR AR24388272A patent/AR200387A1/es active
- 1972-09-04 ES ES406374A patent/ES406374A1/es not_active Expired
- 1972-09-04 JP JP8802072A patent/JPS4885584A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH551430A (fr) | 1974-07-15 |
| FR2154449A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| AT320655B (de) | 1975-02-25 |
| GB1368256A (en) | 1974-09-25 |
| JPS4885584A (enrdf_load_stackoverflow) | 1973-11-13 |
| IE37697L (en) | 1973-03-04 |
| AR200387A1 (es) | 1974-11-08 |
| NL7211694A (enrdf_load_stackoverflow) | 1973-03-06 |
| BE788280A (fr) | 1973-02-28 |
| AU4594072A (en) | 1974-02-28 |
| DE2242382A1 (de) | 1973-03-15 |
| CH554899A (fr) | 1974-10-15 |
| IE37697B1 (en) | 1977-09-28 |
| AT321307B (de) | 1975-03-25 |
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