ES403523A1 - Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES403523A1
ES403523A1 ES403523A ES403523A ES403523A1 ES 403523 A1 ES403523 A1 ES 403523A1 ES 403523 A ES403523 A ES 403523A ES 403523 A ES403523 A ES 403523A ES 403523 A1 ES403523 A1 ES 403523A1
Authority
ES
Spain
Prior art keywords
formula
aminocephalosporanic acid
translation
derived
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES403523A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Industrial Products SA
Original Assignee
Gema SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gema SA filed Critical Gema SA
Priority to ES403523A priority Critical patent/ES403523A1/en
Publication of ES403523A1 publication Critical patent/ES403523A1/en
Expired legal-status Critical Current

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Abstract

Preparation procedure for N-acyl-derivatives of 7-aminocephalosporanic acid, characterized in that a dimethylformiminium N-halide-halosulfite of formula **(See formula)** where X = chlorine, bromine, iodine, with a carboxylic acid of the following general formula R - COOH R being an aromatic, alkanoaromatic, heterocidic group, suspended or dissolved in an inert medium and at a temperature of -20 to + 20º; the resulting mixture is then added gradually, over a solution or suspension of a 7-aminocephalosporanic acid of formula **(See formula)** R1 being an ester, hydroxyl, quaternary N-pyridinium group and R2 being hydrogen, an alkali metal, alkaline earth metal, benzathine salt, or internal salt in the case of N-pyridinium compounds, to form an N-acyl- derived from the formula **(See formula)** where R, R1 and R2 have the significance given above, which is isolated by precipitation, by dilution of the reaction mixture in an aliphatic hydrocarbon of 6 to 10 carbon atoms. (Machine-translation by Google Translate, not legally binding)
ES403523A 1972-06-05 1972-06-05 Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) Expired ES403523A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES403523A ES403523A1 (en) 1972-06-05 1972-06-05 Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES403523A ES403523A1 (en) 1972-06-05 1972-06-05 Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES403523A1 true ES403523A1 (en) 1975-05-01

Family

ID=8461355

Family Applications (1)

Application Number Title Priority Date Filing Date
ES403523A Expired ES403523A1 (en) 1972-06-05 1972-06-05 Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES403523A1 (en)

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