ES403523A1 - Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES403523A1 ES403523A1 ES403523A ES403523A ES403523A1 ES 403523 A1 ES403523 A1 ES 403523A1 ES 403523 A ES403523 A ES 403523A ES 403523 A ES403523 A ES 403523A ES 403523 A1 ES403523 A1 ES 403523A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- aminocephalosporanic acid
- translation
- derived
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pyridine Compounds (AREA)
Abstract
Preparation procedure for N-acyl-derivatives of 7-aminocephalosporanic acid, characterized in that a dimethylformiminium N-halide-halosulfite of formula **(See formula)** where X = chlorine, bromine, iodine, with a carboxylic acid of the following general formula R - COOH R being an aromatic, alkanoaromatic, heterocidic group, suspended or dissolved in an inert medium and at a temperature of -20 to + 20º; the resulting mixture is then added gradually, over a solution or suspension of a 7-aminocephalosporanic acid of formula **(See formula)** R1 being an ester, hydroxyl, quaternary N-pyridinium group and R2 being hydrogen, an alkali metal, alkaline earth metal, benzathine salt, or internal salt in the case of N-pyridinium compounds, to form an N-acyl- derived from the formula **(See formula)** where R, R1 and R2 have the significance given above, which is isolated by precipitation, by dilution of the reaction mixture in an aliphatic hydrocarbon of 6 to 10 carbon atoms. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES403523A ES403523A1 (en) | 1972-06-05 | 1972-06-05 | Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES403523A ES403523A1 (en) | 1972-06-05 | 1972-06-05 | Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES403523A1 true ES403523A1 (en) | 1975-05-01 |
Family
ID=8461355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES403523A Expired ES403523A1 (en) | 1972-06-05 | 1972-06-05 | Procedure for the preparation of N-acil derived from 7-aminocephalosporanic acid. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES403523A1 (en) |
-
1972
- 1972-06-05 ES ES403523A patent/ES403523A1/en not_active Expired
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