ES421068A1 - Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES421068A1
ES421068A1 ES421068A ES421068A ES421068A1 ES 421068 A1 ES421068 A1 ES 421068A1 ES 421068 A ES421068 A ES 421068A ES 421068 A ES421068 A ES 421068A ES 421068 A1 ES421068 A1 ES 421068A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES421068A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES421068A1 publication Critical patent/ES421068A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the preparation of new substituted 2-phenylaminoimidazolines of the general formula **(See formula)** wherein R1, R2 and R3, which may be the same or different, signify a hydrogen or fluorine, chlorine or bromine atom, or a methyl, ethyl, methoxy, hydroxy, trifluoromethyl or cyano group and R5 signifies a straight or branched with up to 12 carbon atoms, as well as their acid addition salts, characterized in that a metal salt of 2-phenylamino-imidazoline- (2) of the general formula is reacted **(See formula)** Where R1 through R3 are as defined above, Me + means a metal cation, preferably an alkali metal cation, with a halide of the general formula V Hal - R5 and eventually the product is transformed into an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES421068A 1972-12-02 1973-12-01 Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) Expired ES421068A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722259160 DE2259160A1 (en) 1972-12-02 1972-12-02 NEW SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE, THEIR ACID-ADDITIONAL SALTS AND METHOD FOR MANUFACTURING THE SAME AND THEIR USE AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
ES421068A1 true ES421068A1 (en) 1976-04-16

Family

ID=5863396

Family Applications (2)

Application Number Title Priority Date Filing Date
ES421068A Expired ES421068A1 (en) 1972-12-02 1973-12-01 Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)
ES421067A Expired ES421067A1 (en) 1972-12-02 1973-12-01 Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES421067A Expired ES421067A1 (en) 1972-12-02 1973-12-01 Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
JP (1) JPS4986365A (en)
AT (1) AT326118B (en)
AU (1) AU6309173A (en)
BE (1) BE808150A (en)
DE (1) DE2259160A1 (en)
ES (2) ES421068A1 (en)
FR (1) FR2208671A1 (en)
NL (1) NL7316405A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2636732A1 (en) * 1976-08-14 1978-02-16 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLAMINO IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE2830278A1 (en) * 1978-07-10 1980-01-31 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE2947563A1 (en) * 1979-11-26 1981-06-04 C.H. Boehringer Sohn, 6507 Ingelheim NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE2949287A1 (en) * 1979-12-07 1981-06-11 C.H. Boehringer Sohn, 6507 Ingelheim NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE3200258A1 (en) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO IMIDAZOLIDINE, THE ACID ADDITION SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME
IT1303672B1 (en) * 1998-07-28 2001-02-23 Nicox Sa NITRATED SALTS OF DRUGS ACTIVE IN BONE DISORDERS
US6703409B2 (en) 2002-01-31 2004-03-09 Boehringer Ingelheim Pharma Gmbh & Co Kg 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug
EP1333028A1 (en) * 2002-01-31 2003-08-06 Boehringer Ingelheim Pharma GmbH & Co.KG 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
AU2009257692A1 (en) * 2008-06-09 2009-12-17 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions

Also Published As

Publication number Publication date
JPS4986365A (en) 1974-08-19
AT326118B (en) 1975-11-25
FR2208671A1 (en) 1974-06-28
ATA943273A (en) 1975-02-15
ES421067A1 (en) 1976-04-01
BE808150A (en) 1974-06-04
AU6309173A (en) 1975-06-05
NL7316405A (en) 1974-06-05
DE2259160A1 (en) 1974-06-06

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