ES399728A1 - Benzotriazepines processes for their preparation and compositions incorporating them - Google Patents

Benzotriazepines processes for their preparation and compositions incorporating them

Info

Publication number
ES399728A1
ES399728A1 ES399728A ES399728A ES399728A1 ES 399728 A1 ES399728 A1 ES 399728A1 ES 399728 A ES399728 A ES 399728A ES 399728 A ES399728 A ES 399728A ES 399728 A1 ES399728 A1 ES 399728A1
Authority
ES
Spain
Prior art keywords
carbon atoms
general formula
hydrogen atom
alcohol
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES399728A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES399728A1 publication Critical patent/ES399728A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for preparing compounds of general formula VII: **(See formula)** where R represents a hydrogen atom, an alcohol radical having from 6 to 6 carbon atoms, a cycloalcohyl radical containing from 3 to 7 carbon atoms, an aralcohyl or aryl radical having no more than 8 carbon atoms and optionally substituted in the aromatic nucleus with one or more halogen atoms, with an alcohol or alkoxy radical; R'and R''identical or different from each other, represent a hydrogen atom, a hydroxyl, nitro, lower alkoxy, trifluoromethyl group, or a carboxyl group esterified with an aliphatic alcohol containing 1 to 3 carbon atoms, and of general formula X: **(See formula)** where R, R'and R''retain their meaning indicated above, and R8 represents a hydrogen atom or an alcohol radical containing from 1 to 5 carbon atoms; said process characterized in that a compound of general formula II is reacted: **(See formula)** where R, R'and R''retain their meaning indicated above, with hydrogen sulphide, to obtain a compound of general formula VII: **(See formula)** which is subjected, if desired, to the action of a HalCH2COR8 halogenoketone, where R8 represents a hydrogen atom or an alcohol radical containing from 1 to 5 carbon atoms, to obtain a compound of general formula X: (see formula) (Machine-translation by Google Translate, not legally binding)
ES399728A 1970-07-17 1972-02-12 Benzotriazepines processes for their preparation and compositions incorporating them Expired ES399728A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2757970 1970-07-17

Publications (1)

Publication Number Publication Date
ES399728A1 true ES399728A1 (en) 1974-11-16

Family

ID=11221924

Family Applications (3)

Application Number Title Priority Date Filing Date
ES393364A Expired ES393364A1 (en) 1970-07-17 1971-07-16 Benzotriazepines processes for their preparation and compositions incorporating them
ES399728A Expired ES399728A1 (en) 1970-07-17 1972-02-12 Benzotriazepines processes for their preparation and compositions incorporating them
ES399727A Expired ES399727A1 (en) 1970-07-17 1972-02-12 Benzotriazepines processes for their preparation and compositions incorporating them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES393364A Expired ES393364A1 (en) 1970-07-17 1971-07-16 Benzotriazepines processes for their preparation and compositions incorporating them

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES399727A Expired ES399727A1 (en) 1970-07-17 1972-02-12 Benzotriazepines processes for their preparation and compositions incorporating them

Country Status (14)

Country Link
AR (1) AR192716A1 (en)
AT (1) AT311975B (en)
AU (1) AU3132571A (en)
BE (1) BE770031A (en)
CA (1) CA945160A (en)
CH (2) CH543525A (en)
DE (1) DE2135765A1 (en)
ES (3) ES393364A1 (en)
FR (1) FR2100922B1 (en)
GB (1) GB1350413A (en)
HU (1) HU163435B (en)
IL (1) IL37298A0 (en)
NL (1) NL7109885A (en)
ZA (1) ZA714743B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1056710B (en) * 1967-03-07 1982-02-20 Lab Farmaceutici Maestretti So 4 KETO IH 4,5 DIIDRO 1,2,5 BENZO TRIAZEPINE USEFUL AS DRUGS AND PROCESS FOR THEIR PREPARATION
FR2073289B1 (en) * 1969-12-30 1973-01-12 Roussel Uclaf

Also Published As

Publication number Publication date
IL37298A0 (en) 1971-10-20
HU163435B (en) 1973-08-28
FR2100922A1 (en) 1972-03-24
GB1350413A (en) 1974-04-18
CH543525A (en) 1973-12-14
AT311975B (en) 1973-12-10
ES393364A1 (en) 1973-08-16
AU3132571A (en) 1973-01-18
ES399727A1 (en) 1974-11-16
FR2100922B1 (en) 1974-11-15
CH543524A (en) 1973-10-31
BE770031A (en) 1972-01-17
CA945160A (en) 1974-04-09
ZA714743B (en) 1972-11-29
NL7109885A (en) 1972-01-19
DE2135765A1 (en) 1972-01-20
AR192716A1 (en) 1973-03-14

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