ES399367A1 - Procedure for the production of triazolbenzodiazepinas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the production of triazolbenzodiazepinas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES399367A1
ES399367A1 ES399367A ES399367A ES399367A1 ES 399367 A1 ES399367 A1 ES 399367A1 ES 399367 A ES399367 A ES 399367A ES 399367 A ES399367 A ES 399367A ES 399367 A1 ES399367 A1 ES 399367A1
Authority
ES
Spain
Prior art keywords
group
formula
alkyl
translation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES399367A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES399367A1 publication Critical patent/ES399367A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Procedure for the production of triazobenzodiazepines, of formula I: **(See formula)** wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms inclusive; wherein R1 is hydrogen or alkyl defined as above; wherein R2, R3, R4 and R5 are selected from the group consisting of hydrogen, alkyl defined as above, fluorine, chlorine, bromine, nitro, cyano, trifluoromethyl, alkoxy of 1 to 3 carbon atoms inclusive, amino, alkanoylamino, in the which alkanoyl group has from 1 to 3 carbon atoms inclusive, alkylthio in which the alkyl group is defined as above, alkylsulfinyl in which the alkyl group is defined as above, and dialkylamino in which the chyl group is defined as above, characterized by comprising the following stages: 1. reflux a 2-chloro-4-phenylquinoline of formula II **(See formula)** wherein R2, R3, R4 and R5 are defined as above, with hydrazine hydrate to give the corresponding 2-hydrazino-4-phenylquinoline of formula (III): **(See formula)** where R2, R3, R4 and R5 are defined as above. (Machine-translation by Google Translate, not legally binding)
ES399367A 1971-02-09 1972-02-01 Procedure for the production of triazolbenzodiazepinas. (Machine-translation by Google Translate, not legally binding) Expired ES399367A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11404971A 1971-02-09 1971-02-09

Publications (1)

Publication Number Publication Date
ES399367A1 true ES399367A1 (en) 1974-12-01

Family

ID=22353111

Family Applications (1)

Application Number Title Priority Date Filing Date
ES399367A Expired ES399367A1 (en) 1971-02-09 1972-02-01 Procedure for the production of triazolbenzodiazepinas. (Machine-translation by Google Translate, not legally binding)

Country Status (6)

Country Link
JP (1) JPS4946639B1 (en)
ES (1) ES399367A1 (en)
HU (1) HU164348B (en)
IL (3) IL38505A (en)
PH (3) PH9300A (en)
SU (1) SU444371A3 (en)

Also Published As

Publication number Publication date
IL46953A (en) 1977-07-31
IL38505A (en) 1977-07-31
PH13160A (en) 1980-01-08
JPS4946639B1 (en) 1974-12-11
IL38505A0 (en) 1972-03-28
SU444371A3 (en) 1974-09-25
IL41672A (en) 1977-07-31
PH9300A (en) 1975-08-15
HU164348B (en) 1974-01-28
PH11466A (en) 1978-02-01

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