ES397789A1 - Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES397789A1
ES397789A1 ES397789A ES397789A ES397789A1 ES 397789 A1 ES397789 A1 ES 397789A1 ES 397789 A ES397789 A ES 397789A ES 397789 A ES397789 A ES 397789A ES 397789 A1 ES397789 A1 ES 397789A1
Authority
ES
Spain
Prior art keywords
general formula
translation
procedure
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES397789A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702060720 external-priority patent/DE2060720A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES397789A1 publication Critical patent/ES397789A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Procedure for the preparation of sulfonylureas of the general formula **(See formula)** in which R-1 means a phenyl radical optionally substituted by a chlorine or bromine atom or by a methyl or trifluoromethyl group, as well as its alkali metal and alkaline earth metal salts, characterized in that a sulfonamide of the general formula **(See formula)** in which R1 is as previously defined or one of its alkali metal salts, with a compound of the general formula **(See formula)** wherein X means a halogen atom, an amino group or a hydroxy or mercapto group substituted by an optionally substituted alcoholic, aralcohyl or aryl radical in any way, optionally in the presence of a tertiary organic or inorganic base; and the compounds of the general formula I obtained are transformed, if desired, into their alkali metal and alkaline earth metal salts. (Machine-translation by Google Translate, not legally binding)
ES397789A 1970-12-10 1971-12-09 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding) Expired ES397789A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702060720 DE2060720A1 (en) 1969-07-01 1970-12-10 1-(2-(2-phenylpropionyl) tetrahydroisoquinolinyl-7-sulphonyl)-3- - cyclohexylamino-ureas prepn - useful as hypoglycaemics

Publications (1)

Publication Number Publication Date
ES397789A1 true ES397789A1 (en) 1974-06-01

Family

ID=5790525

Family Applications (7)

Application Number Title Priority Date Filing Date
ES397789A Expired ES397789A1 (en) 1970-12-10 1971-12-09 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES398954A Expired ES398954A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES398956A Expired ES398956A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES398958A Expired ES398958A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES72398953A Expired ES398953A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES398955A Expired ES398955A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES398957A Expired ES398957A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)

Family Applications After (6)

Application Number Title Priority Date Filing Date
ES398954A Expired ES398954A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES398956A Expired ES398956A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES398958A Expired ES398958A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES72398953A Expired ES398953A1 (en) 1970-12-10 1972-01-18 PROCEDURE FOR THE PREPARATION OF SULFONYLUREAS.
ES398955A Expired ES398955A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES398957A Expired ES398957A1 (en) 1970-12-10 1972-01-18 Procedure for the preparation of sulfonilureas. (Machine-translation by Google Translate, not legally binding)

Country Status (9)

Country Link
AT (7) AT317915B (en)
BG (6) BG20786A3 (en)
CA (1) CA960675A (en)
CH (4) CH567479A5 (en)
DD (1) DD96068A5 (en)
ES (7) ES397789A1 (en)
HU (1) HU163804B (en)
RO (1) RO61566A (en)
SE (1) SE378244B (en)

Also Published As

Publication number Publication date
AT313914B (en) 1974-03-11
ES398953A1 (en) 1974-10-01
ES398954A1 (en) 1974-10-01
RO61566A (en) 1977-01-15
SE378244B (en) 1975-08-25
CA960675A (en) 1975-01-07
BG20573A3 (en) 1975-12-05
AT317913B (en) 1974-09-25
BG20343A3 (en) 1975-11-05
DD96068A5 (en) 1973-03-05
HU163804B (en) 1973-10-27
ES398957A1 (en) 1974-10-16
CH567479A5 (en) 1975-10-15
BG20572A3 (en) 1975-12-05
AT317912B (en) 1974-09-25
BG20786A3 (en) 1975-12-20
BG19137A3 (en) 1975-04-30
AT317916B (en) 1974-09-25
BG20571A3 (en) 1975-12-05
AT317917B (en) 1974-09-25
CH567478A5 (en) 1975-10-15
ES398956A1 (en) 1974-10-16
CH568292A5 (en) 1975-10-31
CH568293A5 (en) 1975-10-31
AT317915B (en) 1974-09-25
AT317914B (en) 1974-09-25
ES398955A1 (en) 1974-10-16
ES398958A1 (en) 1974-10-16

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