ES397400A1 - Amidoxime-o-carbamates - Google Patents
Amidoxime-o-carbamatesInfo
- Publication number
- ES397400A1 ES397400A1 ES397400A ES397400A ES397400A1 ES 397400 A1 ES397400 A1 ES 397400A1 ES 397400 A ES397400 A ES 397400A ES 397400 A ES397400 A ES 397400A ES 397400 A1 ES397400 A1 ES 397400A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- carbon atoms
- acid addition
- addition salts
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms
Abstract
Novel amidoxime o - carbamates of the Formula I wherein R is an aliphatic hydrocarbon radical having 3 to 12 carbon atoms, and each of R 1 and R 2 , which may be the same or different is H or C 1-3 alkyl, the sum of the carbon atoms in R 1 and R 2 not exceeding 3 and acid addition salts thereof are prepared by reacting amidoximes of the general Formula II with alkali metal cyanates, or with C 1-3 alkyl isocyanates of the formula or with carbamoyl halides of the formula wherein X is halogen. Pentanamidoxime is obtained by reacting valeronitrile with hydroxylamine hydrochloride. Pharmaceutical compositions, suitable for oral or parenteral administration and having antihypertensive activity, contain the above novel compounds or acid addition salts thereof, and pharmaceutically acceptable carriers or diluents.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78995969A | 1969-01-08 | 1969-01-08 | |
US88473769A | 1969-12-12 | 1969-12-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES397400A1 true ES397400A1 (en) | 1975-03-16 |
Family
ID=27120978
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES375236A Expired ES375236A1 (en) | 1969-01-08 | 1970-01-07 | Amidoxime-o-carbamates |
ES397400A Expired ES397400A1 (en) | 1969-01-08 | 1971-11-26 | Amidoxime-o-carbamates |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES375236A Expired ES375236A1 (en) | 1969-01-08 | 1970-01-07 | Amidoxime-o-carbamates |
Country Status (12)
Country | Link |
---|---|
AR (1) | AR192723A1 (en) |
BE (1) | BE743784A (en) |
CH (1) | CH534135A (en) |
DE (1) | DE2000492B2 (en) |
DK (1) | DK125390B (en) |
ES (2) | ES375236A1 (en) |
FR (1) | FR2034457B1 (en) |
GB (1) | GB1244592A (en) |
IL (1) | IL33612A (en) |
LU (1) | LU60149A1 (en) |
NL (1) | NL7000156A (en) |
SE (1) | SE350032B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA731406B (en) * | 1972-04-18 | 1974-10-30 | Du Pont | New antihypertensive agents |
NL7908922A (en) * | 1979-12-12 | 1981-07-16 | Akzo Nv | CARBOXIMIDAMIDE DERIVATIVES. |
-
1969
- 1969-12-26 IL IL33612A patent/IL33612A/en unknown
- 1969-12-29 BE BE743784D patent/BE743784A/xx not_active IP Right Cessation
-
1970
- 1970-01-06 CH CH6170A patent/CH534135A/en not_active IP Right Cessation
- 1970-01-07 ES ES375236A patent/ES375236A1/en not_active Expired
- 1970-01-07 DK DK6170AA patent/DK125390B/en unknown
- 1970-01-07 GB GB885/70A patent/GB1244592A/en not_active Expired
- 1970-01-07 DE DE19702000492 patent/DE2000492B2/en active Pending
- 1970-01-07 LU LU60149D patent/LU60149A1/xx unknown
- 1970-01-07 NL NL7000156A patent/NL7000156A/xx unknown
- 1970-01-07 SE SE00113/70A patent/SE350032B/xx unknown
- 1970-01-08 FR FR707000586A patent/FR2034457B1/fr not_active Expired
-
1971
- 1971-10-20 AR AR238570A patent/AR192723A1/en active
- 1971-11-26 ES ES397400A patent/ES397400A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL33612A0 (en) | 1970-03-22 |
DE2000492B2 (en) | 1976-03-04 |
ES375236A1 (en) | 1972-08-01 |
AR192723A1 (en) | 1973-03-14 |
GB1244592A (en) | 1971-09-02 |
CH534135A (en) | 1973-02-28 |
SE350032B (en) | 1972-10-16 |
FR2034457B1 (en) | 1973-04-06 |
BE743784A (en) | 1970-05-28 |
IL33612A (en) | 1973-06-29 |
DE2000492A1 (en) | 1970-07-16 |
NL7000156A (en) | 1970-07-10 |
FR2034457A1 (en) | 1970-12-11 |
DK125390B (en) | 1973-02-12 |
LU60149A1 (en) | 1970-03-09 |
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