ES396708A1 - Un procedimiento para producir esteres de protaglandina. - Google Patents
Un procedimiento para producir esteres de protaglandina.Info
- Publication number
- ES396708A1 ES396708A1 ES396708A ES396708A ES396708A1 ES 396708 A1 ES396708 A1 ES 396708A1 ES 396708 A ES396708 A ES 396708A ES 396708 A ES396708 A ES 396708A ES 396708 A1 ES396708 A1 ES 396708A1
- Authority
- ES
- Spain
- Prior art keywords
- production
- prostaglandin
- reacting
- prostaglandin esters
- amine salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Prostaglandin esters Chemical class 0.000 title abstract 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9891970A JPS4920766B1 (da) | 1970-11-10 | 1970-11-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES396708A1 true ES396708A1 (es) | 1975-04-16 |
Family
ID=14232524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES396708A Expired ES396708A1 (es) | 1970-11-10 | 1971-11-05 | Un procedimiento para producir esteres de protaglandina. |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS4920766B1 (da) |
AR (1) | AR193625A1 (da) |
BE (1) | BE775106A (da) |
CA (1) | CA951314A (da) |
CH (1) | CH559716A5 (da) |
DD (1) | DD95372A5 (da) |
DE (1) | DE2155546A1 (da) |
DK (1) | DK128733B (da) |
ES (1) | ES396708A1 (da) |
FR (1) | FR2113883B1 (da) |
GB (1) | GB1362956A (da) |
HU (1) | HU162848B (da) |
NL (1) | NL7115393A (da) |
NO (1) | NO133325C (da) |
SU (1) | SU433670A3 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4163108A (en) * | 1967-02-16 | 1979-07-31 | Lever Brothers Company | Prostaglandins |
JPS4942648A (da) * | 1972-08-24 | 1974-04-22 | ||
US3984424A (en) * | 1972-11-08 | 1976-10-05 | Pfizer Inc. | P-biphenyl esters of 15-substituted-ω-pentanorprostaglandins |
US3989736A (en) * | 1973-01-08 | 1976-11-02 | Pfizer Inc. | Prostaglandin 5-indanyl esters |
US3968140A (en) * | 1974-01-08 | 1976-07-06 | The Upjohn Company | Substituted anilide esters of PGE1 |
US3931281A (en) * | 1974-01-08 | 1976-01-06 | The Upjohn Company | Substituted anilide ester of PGA2 |
US3890372A (en) * | 1974-01-08 | 1975-06-17 | Upjohn Co | Amino substituted phenyl and naphthyl esters of PGF{HD 2{301 {B - type compounds |
US3959319A (en) * | 1974-01-08 | 1976-05-25 | The Upjohn Company | Phenyl and naphthyl esters of PGF2 α type prostaglandins |
US3962289A (en) * | 1974-01-08 | 1976-06-08 | The Upjohn Company | Esters of PGA2 and p-tritylphenol |
US3988355A (en) * | 1974-01-08 | 1976-10-26 | The Upjohn Company | Substituted phenyl and naphthyl esters of PGE1 |
US4013707A (en) * | 1974-01-08 | 1977-03-22 | The Upjohn Company | Substituted phenyl esters of PGA1 |
US3932486A (en) * | 1974-01-08 | 1976-01-13 | The Upjohn Company | Substituted tolyl esters of PGA2 |
US3969464A (en) * | 1974-01-08 | 1976-07-13 | The Upjohn Company | Polycyclic aromatic esters of PGA1 |
US3931285A (en) * | 1974-01-08 | 1976-01-06 | The Upjohn Company | Substituted tolyl esters of PGE1 |
US4013693A (en) * | 1974-01-08 | 1977-03-22 | The Upjohn Company | Substituted phenyl esters of PGA1 |
US3948970A (en) * | 1974-01-08 | 1976-04-06 | The Upjohn Company | Substituted tolyl esters of PGA1 |
US3987067A (en) * | 1974-01-08 | 1976-10-19 | The Upjohn Company | Substituted aromatic esters of PGF2.sub.α |
US3998869A (en) * | 1974-11-14 | 1976-12-21 | The Upjohn Company | Substituted anilide esters of 16-substituted PGE2 |
US4042606A (en) * | 1974-12-12 | 1977-08-16 | The Upjohn Company | Substituted phenyl esters of PGA2 |
US4058551A (en) * | 1974-12-12 | 1977-11-15 | The Upjohn Company | Substituted phenyl esters of PGA2 |
JPS5420344U (da) * | 1977-07-13 | 1979-02-09 | ||
ES2213504T1 (es) † | 1988-09-06 | 2004-09-01 | Pfizer Health Ab | Derivados de prostaglandina para el tratamiento del glaucoma o hipertension ocular. |
AU8475301A (en) | 2000-08-07 | 2002-02-18 | Univ Vanderbilt | Detection of cox-2 activity and anandamide metabolites |
US7314709B2 (en) | 2002-08-06 | 2008-01-01 | Vanderbilt University | Compositions and methods for detecting and quantifying COX-2 activity by lipoamino acid metabolism |
EP2084124B9 (en) | 2006-10-02 | 2015-07-01 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates |
JP5925158B2 (ja) * | 2013-06-04 | 2016-05-25 | テックフィールズ バイオケム カンパニー リミテッド | 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ |
JP6030168B2 (ja) * | 2015-03-09 | 2016-11-24 | テックフィールズ バイオケム カンパニー リミテッド | 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ |
JP6306067B2 (ja) * | 2016-01-08 | 2018-04-04 | テックフィールズ バイオケム カンパニー リミテッド | 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ |
CN109400513B (zh) * | 2018-11-26 | 2020-06-09 | 武汉嘉诺康医药技术有限公司 | 一种卡前列素的纯化方法 |
-
1970
- 1970-11-10 JP JP9891970A patent/JPS4920766B1/ja active Pending
-
1971
- 1971-11-05 GB GB5161571A patent/GB1362956A/en not_active Expired
- 1971-11-05 ES ES396708A patent/ES396708A1/es not_active Expired
- 1971-11-09 HU HUOO000176 patent/HU162848B/hu unknown
- 1971-11-09 DK DK549271A patent/DK128733B/da unknown
- 1971-11-09 NO NO413771A patent/NO133325C/no unknown
- 1971-11-09 DE DE19712155546 patent/DE2155546A1/de active Pending
- 1971-11-09 DD DD15881771A patent/DD95372A5/xx unknown
- 1971-11-09 CA CA127,208,A patent/CA951314A/en not_active Expired
- 1971-11-09 FR FR7140157A patent/FR2113883B1/fr not_active Expired
- 1971-11-09 AR AR23895871A patent/AR193625A1/es active
- 1971-11-09 NL NL7115393A patent/NL7115393A/xx unknown
- 1971-11-09 BE BE775106A patent/BE775106A/xx unknown
- 1971-11-10 CH CH1634271A patent/CH559716A5/xx not_active IP Right Cessation
- 1971-11-10 SU SU1715000A patent/SU433670A3/ru active
Also Published As
Publication number | Publication date |
---|---|
BE775106A (fr) | 1972-03-01 |
DE2155546A1 (da) | 1972-05-18 |
DK128733B (da) | 1974-06-24 |
DD95372A5 (da) | 1973-02-05 |
SU433670A3 (da) | 1974-06-25 |
HU162848B (da) | 1973-04-28 |
FR2113883A1 (da) | 1972-06-30 |
GB1362956A (en) | 1974-08-07 |
NL7115393A (da) | 1972-05-15 |
CA951314A (en) | 1974-07-16 |
AR193625A1 (es) | 1973-05-11 |
CH559716A5 (da) | 1975-03-14 |
JPS4920766B1 (da) | 1974-05-27 |
NO133325B (da) | 1976-01-05 |
FR2113883B1 (da) | 1975-08-01 |
NO133325C (da) | 1976-04-12 |
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