ES391800A1 - Preparation of phenylaminoethanols - Google Patents

Preparation of phenylaminoethanols

Info

Publication number
ES391800A1
ES391800A1 ES391800A ES391800A ES391800A1 ES 391800 A1 ES391800 A1 ES 391800A1 ES 391800 A ES391800 A ES 391800A ES 391800 A ES391800 A ES 391800A ES 391800 A1 ES391800 A1 ES 391800A1
Authority
ES
Spain
Prior art keywords
formula
compound
formaldehyde
preparation
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES391800A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allen and Hanburys Ltd
Original Assignee
Allen and Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allen and Hanburys Ltd filed Critical Allen and Hanburys Ltd
Publication of ES391800A1 publication Critical patent/ES391800A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/84—Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

A procedure for the preparation of phenylaminoethanol derivatives of formula I: ** (See formula) ** where R1 represents a hydrogen atom or a benzyl group; and R2 represents a hydrogen atom or a straight or branched chain alkyl radical containing from 1 to 6 carbon atoms or an arylalkyl radical; whose procedure is to treat a compound of formula II ** (See formula) ** where R1 and R2 have the meaning given above, with formaldehyde or a formaldehyde-forming compound, in the presence of a strong base and an alkali metal borate, and, optionally, when R1 is benzyl, debenzylate to obtain the compound where R1 is hydrogen. (Machine-translation by Google Translate, not legally binding)
ES391800A 1970-06-02 1971-05-31 Preparation of phenylaminoethanols Expired ES391800A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26523/70A GB1298284A (en) 1970-06-02 1970-06-02 Preparation of phenylaminoethanols

Publications (1)

Publication Number Publication Date
ES391800A1 true ES391800A1 (en) 1974-11-01

Family

ID=10244972

Family Applications (1)

Application Number Title Priority Date Filing Date
ES391800A Expired ES391800A1 (en) 1970-06-02 1971-05-31 Preparation of phenylaminoethanols

Country Status (14)

Country Link
JP (1) JPS5216102B1 (en)
AT (1) AT308724B (en)
CA (1) CA989418A (en)
CH (1) CH558329A (en)
DE (1) DE2127177C3 (en)
DK (1) DK125388B (en)
ES (1) ES391800A1 (en)
FI (1) FI56823C (en)
GB (1) GB1298284A (en)
IL (1) IL36836A (en)
NL (1) NL174040C (en)
NO (1) NO130312B (en)
SE (1) SE376764B (en)
YU (1) YU34979B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51118737A (en) * 1975-04-10 1976-10-18 Shionogi & Co Ltd Novel process for preparation of monosubstituted aminobenzylalcohols a t o-n position
US4952729A (en) * 1986-09-05 1990-08-28 Schering-Plough Corp. Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol
EP0259159A3 (en) * 1986-09-05 1989-08-09 Schering Corporation Method for the preparation of alpha1- [[(1,1-Dimethylethyl) amino] methyl]-4-hydroxy-1,3-benzenedimethanol, and intermediates used in its preparation

Also Published As

Publication number Publication date
GB1298284A (en) 1972-11-29
IL36836A0 (en) 1971-07-28
NL174040B (en) 1983-11-16
DE2127177B2 (en) 1980-05-22
YU34979B (en) 1980-06-30
JPS5216102B1 (en) 1977-05-06
NL7107588A (en) 1971-12-06
NL174040C (en) 1984-04-16
SE376764B (en) 1975-06-09
YU127171A (en) 1979-12-31
DK125388B (en) 1973-02-12
AT308724B (en) 1973-07-25
CA989418A (en) 1976-05-18
DE2127177C3 (en) 1981-01-29
DE2127177A1 (en) 1971-12-09
CH558329A (en) 1975-01-31
FI56823C (en) 1980-04-10
IL36836A (en) 1973-07-30
FI56823B (en) 1979-12-31
NO130312B (en) 1974-08-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19840227