ES389055A1 - Antibiotic purification procedure. (Machine-translation by Google Translate, not legally binding) - Google Patents

Antibiotic purification procedure. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES389055A1
ES389055A1 ES389055A ES389055A ES389055A1 ES 389055 A1 ES389055 A1 ES 389055A1 ES 389055 A ES389055 A ES 389055A ES 389055 A ES389055 A ES 389055A ES 389055 A1 ES389055 A1 ES 389055A1
Authority
ES
Spain
Prior art keywords
antibiotic
translation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES389055A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES389055A1 publication Critical patent/ES389055A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A process for the recovery of the antibiotic 7- (d-5-amino-5-carboxylaramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or a salt thereof from the impure aqueous solutions they contain said antibiotic, which method consists of passing a fermentation broth or a solution containing said antibiotic through a column of an ion exchange resin, selected from the group formed by anion exchange resins and strongly acidic cation exchange resins, elute the adsorbate in resin with an eluting solvent, collect the eluates and combine the active fractions. (Machine-translation by Google Translate, not legally binding)
ES389055A 1970-03-13 1971-03-09 Antibiotic purification procedure. (Machine-translation by Google Translate, not legally binding) Expired ES389055A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1949770A 1970-03-13 1970-03-13
US9667470A 1970-12-09 1970-12-09

Publications (1)

Publication Number Publication Date
ES389055A1 true ES389055A1 (en) 1974-02-16

Family

ID=26692278

Family Applications (1)

Application Number Title Priority Date Filing Date
ES389055A Expired ES389055A1 (en) 1970-03-13 1971-03-09 Antibiotic purification procedure. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
CH (1) CH552625A (en)
CS (1) CS179951B2 (en)
ES (1) ES389055A1 (en)
NL (1) NL7103135A (en)

Also Published As

Publication number Publication date
NL7103135A (en) 1971-09-15
CS179951B2 (en) 1977-12-30
CH552625A (en) 1974-08-15

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