ES330391A1 - A procedure for the stabilization of 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-ona. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the stabilization of 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-ona. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES330391A1
ES330391A1 ES0330391A ES330391A ES330391A1 ES 330391 A1 ES330391 A1 ES 330391A1 ES 0330391 A ES0330391 A ES 0330391A ES 330391 A ES330391 A ES 330391A ES 330391 A1 ES330391 A1 ES 330391A1
Authority
ES
Spain
Prior art keywords
benzodiazepin
dihydro
nitro
stabilization
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0330391A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES330391A1 publication Critical patent/ES330391A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the stabilization of 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one, characterized by adsorbing this benzodiazepine derivative in an acid ion exchange resin, susceptible to adsorption and, if desired, by converting the product thus obtained into a suspension syrup. (Machine-translation by Google Translate, not legally binding)
ES0330391A 1965-08-20 1966-08-19 A procedure for the stabilization of 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-ona. (Machine-translation by Google Translate, not legally binding) Expired ES330391A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1177965 1965-08-20

Publications (1)

Publication Number Publication Date
ES330391A1 true ES330391A1 (en) 1967-10-16

Family

ID=4376790

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0330391A Expired ES330391A1 (en) 1965-08-20 1966-08-19 A procedure for the stabilization of 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-ona. (Machine-translation by Google Translate, not legally binding)

Country Status (14)

Country Link
JP (1) JPS507079B1 (en)
BE (1) BE685589A (en)
DE (1) DE1617513C3 (en)
DK (1) DK111277B (en)
ES (1) ES330391A1 (en)
FI (1) FI45726C (en)
FR (1) FR6063M (en)
GB (1) GB1101366A (en)
IL (1) IL26306A (en)
IT (1) IT1053660B (en)
MY (1) MY6900059A (en)
NL (1) NL6610569A (en)
NO (1) NO120752B (en)
SE (1) SE351978B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020032245A1 (en) * 2000-07-27 2002-03-14 Lyn Hughes Resinate composition
US20020031490A1 (en) * 2000-07-27 2002-03-14 Bellamy Simon Andrew Method for preparing resinates
US20030059397A1 (en) * 2001-09-17 2003-03-27 Lyn Hughes Dosage forms
DE60226899D1 (en) * 2002-01-18 2008-07-10 Rohm & Haas USE OF A RESINATE FOR PRODUCING A FORMULATION TO END SMOKING

Also Published As

Publication number Publication date
MY6900059A (en) 1969-12-31
SE351978B (en) 1972-12-18
BE685589A (en) 1967-02-17
JPS507079B1 (en) 1975-03-20
IL26306A (en) 1970-02-19
DE1617513A1 (en) 1970-12-23
FI45726C (en) 1972-09-11
DE1617513C3 (en) 1974-04-18
NL6610569A (en) 1967-02-21
GB1101366A (en) 1968-01-31
DE1617513B2 (en) 1973-08-16
NO120752B (en) 1970-11-30
FR6063M (en) 1968-05-27
IT1053660B (en) 1981-10-10
DK111277B (en) 1968-07-15
FI45726B (en) 1972-05-31

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