ES386962A2 - Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES386962A2
ES386962A2 ES386962A ES386962A ES386962A2 ES 386962 A2 ES386962 A2 ES 386962A2 ES 386962 A ES386962 A ES 386962A ES 386962 A ES386962 A ES 386962A ES 386962 A2 ES386962 A2 ES 386962A2
Authority
ES
Spain
Prior art keywords
penicillins
translation
procedure
obtaining
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES386962A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Industrial Products SA
Original Assignee
Gema SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gema SA filed Critical Gema SA
Priority to ES386962A priority Critical patent/ES386962A2/en
Priority to BE762311A priority patent/BE762311A/en
Priority to CH162471A priority patent/CH549049A/en
Priority to DE19712105166 priority patent/DE2105166A1/en
Priority to AT97271A priority patent/AT314730B/en
Priority to NL7101575A priority patent/NL7101575A/xx
Publication of ES386962A2 publication Critical patent/ES386962A2/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Improvements in the patent of invention no. 376,271 by "procedure for the preparation of semisynthesis penicillins", according to which the intermediate resulting from the combination of a dimethylformamide N-halidehalosulfite and a carboxylic acid is reacted with a tertiary amine salt 6-apa in the presence of fatty acids, characterized in that to the transformation product, water and a aldehyde or a low molecular weight ketone are added, adjusting the ph from 2 to 2.5, obtaining by decantation an organic phase, which is again adjusted to ph 6-6.5 with 2-ethylhexanoate sodium and then by dilution in an aliphatic hydrocarbon, precipitating the corresponding penicillin. (Machine-translation by Google Translate, not legally binding)
ES386962A 1970-02-05 1970-12-31 Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding) Expired ES386962A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES386962A ES386962A2 (en) 1970-12-31 1970-12-31 Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding)
BE762311A BE762311A (en) 1970-02-05 1971-01-29 PROCESS FOR OBTAINING SEMI-SYNTHETIC PENICILLINS AND PRODUCTS THUS OBTAINED
CH162471A CH549049A (en) 1970-02-05 1971-02-02 PROCESS FOR OBTAINING PENICILLINS AND PENICILLINS THUS OBTAINED.
DE19712105166 DE2105166A1 (en) 1970-02-05 1971-02-04 Semi-synthetic penicillins prodn
AT97271A AT314730B (en) 1970-02-05 1971-02-05 Process for the production of semi-synthetic penicillins
NL7101575A NL7101575A (en) 1970-02-05 1971-02-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES386962A ES386962A2 (en) 1970-12-31 1970-12-31 Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES386962A2 true ES386962A2 (en) 1973-04-01

Family

ID=8457586

Family Applications (1)

Application Number Title Priority Date Filing Date
ES386962A Expired ES386962A2 (en) 1970-02-05 1970-12-31 Procedure for the obtaining of penicillins of semisintesis. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES386962A2 (en)

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170703