ES420360A2 - Phenothiazine derivatives - Google Patents

Phenothiazine derivatives

Info

Publication number
ES420360A2
ES420360A2 ES420360A ES420360A ES420360A2 ES 420360 A2 ES420360 A2 ES 420360A2 ES 420360 A ES420360 A ES 420360A ES 420360 A ES420360 A ES 420360A ES 420360 A2 ES420360 A2 ES 420360A2
Authority
ES
Spain
Prior art keywords
methyl
phenothiazine
piperidino
trifluoromethyl
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES420360A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES420360A2 publication Critical patent/ES420360A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Improvements introduced in the object of the main patent No. 412,585 applied for on March 13, 1973 by: "A process for the preparation of derivatives of (alkoxy-4-alcohol-4-piperidino-alcoholic) -l0-phenothiazines" according to which for the preparation of {[(decanoyloxy-2-ethoxy) -4-methyl-4-piperidino] -3-propyl} -10-trifluoromethyl-2-phenothiazine, of {[([methyl-2-heptanoyloxy] -2 -ethoxy) -4-methyl-4-piperidino] -3-propyl} -10-trifluoromethyl-2-phenothiazine, and of {[(hexadecanoyloxy-2-ethoxy) -4-methyl-4-piperidino] -3- propyl} -10-trifluoromethyl-2-phenothiazine, as well as its salts, such improvements include reacting (chloro-3-propyl) -10-trifluoromethyl-2-phenothiazine with (methyl-4-piperidyl-4) - oxy-2-ethanol to obtain {[(hydroxy-2-ethoxy) -4-methyl-4-piperidino] -3-propyl} -10-trifluoromethyl-2-phenothiazine which is reacted with an acid chloride of the formula Cl-CO-R3 in which -CO-R3 represents a decanoyl, methyl-2-heptanoyl or hexadecanoyl radical and, if desired, is reacted, on the obtained product, a mineral or organic acid to form its salt. (Machine-translation by Google Translate, not legally binding)
ES420360A 1972-11-09 1973-11-08 Phenothiazine derivatives Expired ES420360A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7239673A FR2205317B2 (en) 1972-11-09 1972-11-09

Publications (1)

Publication Number Publication Date
ES420360A2 true ES420360A2 (en) 1977-07-01

Family

ID=9106882

Family Applications (1)

Application Number Title Priority Date Filing Date
ES420360A Expired ES420360A2 (en) 1972-11-09 1973-11-08 Phenothiazine derivatives

Country Status (10)

Country Link
JP (1) JPS4993376A (en)
AU (1) AU6230973A (en)
BE (1) BE807072R (en)
DE (1) DE2356168A1 (en)
ES (1) ES420360A2 (en)
FR (1) FR2205317B2 (en)
GB (1) GB1393490A (en)
IL (1) IL43544A (en)
NL (1) NL7315410A (en)
ZA (1) ZA738627B (en)

Also Published As

Publication number Publication date
IL43544A (en) 1976-05-31
JPS4993376A (en) 1974-09-05
GB1393490A (en) 1975-05-07
AU6230973A (en) 1975-05-08
DE2356168A1 (en) 1974-05-22
BE807072R (en) 1974-05-08
NL7315410A (en) 1974-05-13
ZA738627B (en) 1974-11-27
FR2205317B2 (en) 1975-11-28
FR2205317A2 (en) 1974-05-31

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