ES379815A1 - Proteins - Google Patents

Proteins

Info

Publication number
ES379815A1
ES379815A1 ES379815A ES379815A ES379815A1 ES 379815 A1 ES379815 A1 ES 379815A1 ES 379815 A ES379815 A ES 379815A ES 379815 A ES379815 A ES 379815A ES 379815 A1 ES379815 A1 ES 379815A1
Authority
ES
Spain
Prior art keywords
microbial
physical
strains
residue
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES379815A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES379815A1 publication Critical patent/ES379815A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Abstract

A slow alpha and beta-glycoprotein preparation procedure, characterized in that a microbial strain chosen from the group consisting of Pneumococci, Streptococci, Neisseria, Staphylococci, Micrococci, Klebsellia Pneumoniae and Hemophilus Influenzae, or a mixture of two or more of these strains or of an association of the different types of one of these strains, after full development, the microbial bodies are harvested manually or automatically, the microbial bodies are put back into suspension in a aqueous medium, the lysis of the microbial body is carried out by chemical, physical or enzymatic means, the waste is separated from microbial bodies by the usual physical means, the transparent solution thus obtained is evaporated, the residue is subjected to the action of one or various lipid solvents, the delipidized product is re-dissolved in an aqueous solvent, which is discharged from the Proteins by physical or chemical means, the precipitate of protides thus formed is separated, the slow glycoproteins are selectively precipitated, from the residue deprotected in aqueous medium, by the addition of a solvent or a mixture of solvents miscible with water and purified, if it is necessary, by the usual techniques of biochemistry. (Machine-translation by Google Translate, not legally binding)
ES379815A 1969-05-20 1970-05-19 Proteins Expired ES379815A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6916297A FR2043475A1 (en) 1969-05-20 1969-05-20

Publications (1)

Publication Number Publication Date
ES379815A1 true ES379815A1 (en) 1972-09-01

Family

ID=9034297

Family Applications (1)

Application Number Title Priority Date Filing Date
ES379815A Expired ES379815A1 (en) 1969-05-20 1970-05-19 Proteins

Country Status (11)

Country Link
BE (1) BE750641A (en)
CA (1) CA929476A (en)
CH (1) CH527272A (en)
DE (1) DE2024586B2 (en)
DK (1) DK129466B (en)
ES (1) ES379815A1 (en)
FR (1) FR2043475A1 (en)
GB (1) GB1317027A (en)
HU (1) HU162857B (en)
NL (2) NL169754C (en)
SE (1) SE392904B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2253499B1 (en) * 1973-12-10 1977-11-04 Fabre Sa Pierre
FR2407262A1 (en) * 1977-10-27 1979-05-25 Cassenne Lab Sa NEW POLYSACCHARIDES MICROBIAL BODY EXTRACTS OF HAEMOPHILUS INFLUENZAE, PROCESS FOR THE PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS OF THESE NEW PRODUCTS
NZ188211A (en) * 1977-10-28 1984-09-28 American Cyanamid Co Isolation of polyribosyl ribitol phosphate(prp)from haemophilus influenzae type b;vaccine comprising prp and bordetellapertussis antigens
CH633188A5 (en) * 1978-05-26 1982-11-30 Om Laboratoires Sa MEDICINE FOR INFECTIOUS DISEASES OF THE RESPIRATORY TRACT.
US4298596A (en) * 1979-03-29 1981-11-03 Burroughs Wellcome Co. Trypanosoma cruzi glycoprotein vaccine for inducing immunity to Chagas' disease
FR2462477A1 (en) * 1979-07-31 1981-02-13 Cassenne Lab Sa NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
FR2490495A1 (en) * 1980-09-19 1982-03-26 Roussel Uclaf NOVEL HYDROSOLUBLE IMMUNOSTIMULANT GLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PROCESS FOR OBTAINING THEM, USE THEREOF AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
FR2490496A1 (en) * 1980-09-19 1982-03-26 Roussel Uclaf NEW IMMUNOSTIMULANT GLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND COMPOSITIONS COMPRISING THE SAME
WO1983003354A1 (en) * 1982-03-30 1983-10-13 Us Army Neisseria gonorrhoeae vaccine
FR2574429B1 (en) * 1984-12-06 1987-12-11 Roussel Uclaf ACYLGLYCANNES EXTRACTED FROM KLEBSIELLA, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
US4912200A (en) * 1987-05-11 1990-03-27 Schering Corporation Extraction of granulocyte macrophage colony stimulating factor from bacteria
FR2653014B1 (en) * 1989-10-17 1994-09-16 Roussel Uclaf USE OF GLYCOPROTEINS EXTRACTED FROM GRAM (-) BACTERIA FOR THE MANUFACTURE OF COSMETIC OR DERMATOLOGICAL COMPOSITIONS AND COMPOSITIONS CONTAINING THEM.
EP0556521A1 (en) * 1992-01-09 1993-08-25 Becton, Dickinson and Company Sample processing using disinfectant
EP0552571A1 (en) * 1992-01-09 1993-07-28 Becton, Dickinson and Company Release of intracellular components

Also Published As

Publication number Publication date
FR2043475A1 (en) 1971-02-19
CH527272A (en) 1972-08-31
HU162857B (en) 1973-04-28
CA929476A (en) 1973-07-03
DE2024586A1 (en) 1970-11-26
DE2024586B2 (en) 1979-06-07
NL169754C (en) 1982-08-16
GB1317027A (en) 1973-05-16
NL174267B (en)
DK129466C (en) 1975-03-10
NL169754B (en) 1982-03-16
DK129466B (en) 1974-10-14
SE392904B (en) 1977-04-25
BE750641A (en) 1970-11-20
NL7007262A (en) 1970-11-24
DE2024586C3 (en) 1980-02-14

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