ES369991A1 - Procedimiento para producir un compuesto de prostaglandi- nas. - Google Patents
Procedimiento para producir un compuesto de prostaglandi- nas.Info
- Publication number
- ES369991A1 ES369991A1 ES369991A ES369991A ES369991A1 ES 369991 A1 ES369991 A1 ES 369991A1 ES 369991 A ES369991 A ES 369991A ES 369991 A ES369991 A ES 369991A ES 369991 A1 ES369991 A1 ES 369991A1
- Authority
- ES
- Spain
- Prior art keywords
- methylprostaglandin
- ethyl acetate
- see formula
- formula
- fractions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002131 composite material Substances 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
- 150000004702 methyl esters Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002024 ethyl acetate extract Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- XONPDZSGENTBNJ-UHFFFAOYSA-N molecular hydrogen;sodium Chemical compound [Na].[H][H] XONPDZSGENTBNJ-UHFFFAOYSA-N 0.000 abstract 1
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- -1 prostaglandin compound Chemical class 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 229910052938 sodium sulfate Inorganic materials 0.000 abstract 1
- 235000011152 sodium sulphate Nutrition 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 238000002211 ultraviolet spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74816768A | 1968-07-29 | 1968-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES369991A1 true ES369991A1 (es) | 1972-01-01 |
Family
ID=25008303
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES369991A Expired ES369991A1 (es) | 1968-07-29 | 1969-07-29 | Procedimiento para producir un compuesto de prostaglandi- nas. |
| ES394673A Expired ES394673A1 (es) | 1968-07-29 | 1971-08-31 | Procedimiento para producir un compuesto de prostaglandi- nas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES394673A Expired ES394673A1 (es) | 1968-07-29 | 1971-08-31 | Procedimiento para producir un compuesto de prostaglandi- nas. |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE736727A (es) |
| BR (1) | BR6911098D0 (es) |
| CH (1) | CH548971A (es) |
| DE (1) | DE1937921A1 (es) |
| ES (2) | ES369991A1 (es) |
| FR (1) | FR2013926A1 (es) |
| IL (1) | IL32518A (es) |
| NL (1) | NL6911477A (es) |
| PL (1) | PL80229B1 (es) |
| SE (1) | SE377566B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA944358A (en) * | 1970-11-27 | 1974-03-26 | Upjohn Company (The) | Bicyclic acetals and preparation thereof |
| MXPA01009893A (es) | 1999-04-01 | 2003-07-28 | Esperion Therapeutics Inc | Compuestos con eter, composiciones y usos de estos. |
| EP1862444A3 (en) * | 1999-04-01 | 2008-01-09 | Esperion Therapeutics, Inc. | Ether compounds, compositions, and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1198071A (en) * | 1966-08-09 | 1970-07-08 | George Erich Just | Improvements in or relating to Prostaglandin Analogues and the Manufacture thereof |
-
1969
- 1969-07-01 IL IL32518A patent/IL32518A/xx unknown
- 1969-07-25 SE SE6910520A patent/SE377566B/xx unknown
- 1969-07-25 DE DE19691937921 patent/DE1937921A1/de active Pending
- 1969-07-25 NL NL6911477A patent/NL6911477A/xx unknown
- 1969-07-28 FR FR6925803A patent/FR2013926A1/fr active Granted
- 1969-07-28 BR BR211098/69A patent/BR6911098D0/pt unknown
- 1969-07-28 CH CH1149569A patent/CH548971A/xx not_active IP Right Cessation
- 1969-07-28 PL PL1969135097A patent/PL80229B1/pl unknown
- 1969-07-29 BE BE736727A patent/BE736727A/fr unknown
- 1969-07-29 ES ES369991A patent/ES369991A1/es not_active Expired
-
1971
- 1971-08-31 ES ES394673A patent/ES394673A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2013926A1 (en) | 1970-04-10 |
| DE1937921A1 (de) | 1970-01-29 |
| BR6911098D0 (pt) | 1973-05-31 |
| CH548971A (de) | 1974-05-15 |
| NL6911477A (es) | 1970-02-02 |
| IL32518A (en) | 1974-03-14 |
| IL32518A0 (en) | 1969-09-25 |
| PL80229B1 (en) | 1975-08-30 |
| BE736727A (fr) | 1970-01-29 |
| ES394673A1 (es) | 1974-02-16 |
| SE377566B (es) | 1975-07-14 |
| FR2013926B1 (es) | 1973-01-12 |
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