ES368497A1 - Novel imidazoline derivatives, the preparation thereof and compositions containing the same - Google Patents

Novel imidazoline derivatives, the preparation thereof and compositions containing the same

Info

Publication number
ES368497A1
ES368497A1 ES368497A ES368497A ES368497A1 ES 368497 A1 ES368497 A1 ES 368497A1 ES 368497 A ES368497 A ES 368497A ES 368497 A ES368497 A ES 368497A ES 368497 A1 ES368497 A1 ES 368497A1
Authority
ES
Spain
Prior art keywords
preparation
same
compositions containing
imidazoline derivatives
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES368497A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES368497A1 publication Critical patent/ES368497A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Novel 2 - phenylamino - imidazolines - (2) of the general formula wherein R is a fluorine or chlorine atom or a cyano, trifluoromethyl, C 1-4 alkyl or C 1-4 alkoxy group and X is a fluorine, chlorine or bromine atom, and physiologically acceptable acid addition salts thereof are prepared by bromination of a 2-phenylamino-imidazoline- (2) of the general formula optional conversion of the resulting hydrobromide salt to the corresponding free base and optional conversion of the said free base to a physiologically acceptable acid addition salt thereof other than the hydrobromide salt.
ES368497A 1968-06-21 1969-06-18 Novel imidazoline derivatives, the preparation thereof and compositions containing the same Expired ES368497A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT598868A AT285599B (en) 1968-06-21 1968-06-21 Process for the preparation of new trisubstituted 2-arylaminoimidazolines and their salts

Publications (1)

Publication Number Publication Date
ES368497A1 true ES368497A1 (en) 1971-05-01

Family

ID=3581723

Family Applications (1)

Application Number Title Priority Date Filing Date
ES368497A Expired ES368497A1 (en) 1968-06-21 1969-06-18 Novel imidazoline derivatives, the preparation thereof and compositions containing the same

Country Status (9)

Country Link
AT (1) AT285599B (en)
BE (1) BE734954A (en)
CH (1) CH511856A (en)
DE (1) DE1929950A1 (en)
ES (1) ES368497A1 (en)
FR (1) FR2011408A1 (en)
GB (1) GB1216945A (en)
IL (1) IL32444A0 (en)
NL (1) NL6909515A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2806775A1 (en) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO IMIDAZOLIDINE THEIR ACID ADDITION SALTS, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
DE2949287A1 (en) * 1979-12-07 1981-06-11 C.H. Boehringer Sohn, 6507 Ingelheim NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE3168754D1 (en) * 1980-07-09 1985-03-21 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea
CA1201066A (en) * 1981-11-20 1986-02-25 Alcon Laboratories, Inc. N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4444782A (en) * 1982-12-23 1984-04-24 Smithkline Beckman Corporation 2(4-tert.-Butyl-2,6-dichlorophenyl-imino)imidazolidine and use as an anti-hypertension agent
DE8708009U1 (en) * 1987-06-05 1987-08-20 Lescha Maschinenfabrik Gmbh, 8900 Augsburg, De
DE19514579A1 (en) 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Use of alpha-1-olone agonists for the treatment of urinary incontinence

Also Published As

Publication number Publication date
DE1929950A1 (en) 1970-03-05
NL6909515A (en) 1969-12-23
BE734954A (en) 1969-12-22
CH511856A (en) 1971-08-31
FR2011408A1 (en) 1970-02-27
GB1216945A (en) 1970-12-23
IL32444A0 (en) 1969-08-27
AT285599B (en) 1970-11-10

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