ES359406A1 - Substd salicylanilide cpds anthelmintics - Google Patents

Substd salicylanilide cpds anthelmintics

Info

Publication number
ES359406A1
ES359406A1 ES359406A ES359406A ES359406A1 ES 359406 A1 ES359406 A1 ES 359406A1 ES 359406 A ES359406 A ES 359406A ES 359406 A ES359406 A ES 359406A ES 359406 A1 ES359406 A1 ES 359406A1
Authority
ES
Spain
Prior art keywords
anthelmintics
cpds
haloalkyl
salicylanilide
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES359406A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of ES359406A1 publication Critical patent/ES359406A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
    • A23G9/04—Production of frozen sweets, e.g. ice-cream
    • A23G9/08—Batch production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Improved method of prepn. for cpds. of general formula (I): - n = 0 - 3 - Y = Hal, OH, alkyl, haloalkyl, O alkyl, or NO2. - X and X1 = Hal, alkyl, haloalkyl, NO2, CN, O-haloalkyl, or S-haloalkyl. - Q = O or S - Anthelmintics, esp. active vs. Fasciola hepatica and F. gigantica. - 2-Chloro-4-(m-trifluoromethylphenoxy) benzene-diazonium fluoroborate (3.86 g.), was added (2 h.) to 2-hydroxy-3, 5-di-iodobenzonitrile (3.71 g.) in dioxan (30 ml.) at 65 deg.-75 deg., heated 30 min. at 70 deg., dild. with H2O (30 ml.), stood 17 h., filtered, washed, and recryst. from EtOH, giving (I), m.p. 127-9 deg.
ES359406A 1967-10-23 1968-10-22 Substd salicylanilide cpds anthelmintics Expired ES359406A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2189067 1967-10-23

Publications (1)

Publication Number Publication Date
ES359406A1 true ES359406A1 (en) 1970-06-01

Family

ID=11188282

Family Applications (1)

Application Number Title Priority Date Filing Date
ES359406A Expired ES359406A1 (en) 1967-10-23 1968-10-22 Substd salicylanilide cpds anthelmintics

Country Status (4)

Country Link
BE (1) BE722687A (en)
DE (1) DE1804331A1 (en)
ES (1) ES359406A1 (en)
NL (1) NL6815158A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG50585A1 (en) * 1990-01-18 1998-07-20 Cura Nominees Pty Ltd Glycoalkaloids
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
CU20110244A7 (en) * 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem SPI-ESTEROID SYSTEMS WITH NEUROACTIVE AND ANTI-INFLAMMATORY EFFECTS

Also Published As

Publication number Publication date
DE1804331A1 (en) 1969-05-22
BE722687A (en) 1969-04-22
NL6815158A (en) 1969-04-25

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