ES352666A1 - Un procedimiento para la preparacion de un miembro selec- cionado entre el grupo formado por una pirazinoilguanidina. - Google Patents
Un procedimiento para la preparacion de un miembro selec- cionado entre el grupo formado por una pirazinoilguanidina.Info
- Publication number
- ES352666A1 ES352666A1 ES352666A ES352666A ES352666A1 ES 352666 A1 ES352666 A1 ES 352666A1 ES 352666 A ES352666 A ES 352666A ES 352666 A ES352666 A ES 352666A ES 352666 A1 ES352666 A1 ES 352666A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- halophenyl
- atom
- heterocyclic ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63052167A | 1967-04-13 | 1967-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES352666A1 true ES352666A1 (es) | 1970-01-01 |
Family
ID=24527511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES352666A Expired ES352666A1 (es) | 1967-04-13 | 1968-04-10 | Un procedimiento para la preparacion de un miembro selec- cionado entre el grupo formado por una pirazinoilguanidina. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3527758A (enExample) |
| AT (1) | AT281064B (enExample) |
| BE (1) | BE713471A (enExample) |
| CH (1) | CH512497A (enExample) |
| DE (1) | DE1770174A1 (enExample) |
| ES (1) | ES352666A1 (enExample) |
| FR (1) | FR1559541A (enExample) |
| GB (1) | GB1185408A (enExample) |
| IE (1) | IE32004B1 (enExample) |
| IL (1) | IL29735A (enExample) |
| NL (1) | NL6804247A (enExample) |
| SE (1) | SE354865B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894376A (en) * | 1988-02-26 | 1990-01-16 | Trustees Of The University Of Pennsylvania | Methods of treating diseases characterized by hyperexcitability of neurons |
| TW213903B (enExample) * | 1991-08-16 | 1993-10-01 | Boehringer Ingelheim Kg | |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| EP1646371A4 (en) * | 2003-06-26 | 2010-09-22 | Biotron Ltd | ANTIVIRAL COMPOSITIONS AND METHODS |
| AU2004266704B2 (en) * | 2003-08-18 | 2012-02-23 | Parion Sciences, Inc. | Capped pyrazinoylguanidine sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| US20070099968A1 (en) * | 2004-06-26 | 2007-05-03 | Biotron Limited | Antiviral compounds and methods |
| US7399766B2 (en) * | 2004-08-18 | 2008-07-15 | Parion Sciences, Inc. | Soluble amide & ester pyrazinoylguanidine sodium channel blockers |
| US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| HUE032891T2 (hu) | 2012-12-17 | 2017-11-28 | Parion Sciences Inc | Klórpirazin-karboxamid-származékok nem kielégítõ nyálkahártya-hidratáció által elõsegített megbetegedések kezelésére |
| RU2671976C2 (ru) | 2012-12-17 | 2018-11-08 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4-фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
-
1967
- 1967-04-13 US US630521A patent/US3527758A/en not_active Expired - Lifetime
-
1968
- 1968-03-26 NL NL6804247A patent/NL6804247A/xx unknown
- 1968-04-01 IL IL29735A patent/IL29735A/xx unknown
- 1968-04-02 IE IE377/68A patent/IE32004B1/xx unknown
- 1968-04-04 SE SE04523/68A patent/SE354865B/xx unknown
- 1968-04-08 GB GB06833/68A patent/GB1185408A/en not_active Expired
- 1968-04-08 AT AT343168A patent/AT281064B/de not_active IP Right Cessation
- 1968-04-08 CH CH518468A patent/CH512497A/de not_active IP Right Cessation
- 1968-04-10 DE DE19681770174 patent/DE1770174A1/de active Pending
- 1968-04-10 BE BE713471D patent/BE713471A/xx unknown
- 1968-04-10 ES ES352666A patent/ES352666A1/es not_active Expired
- 1968-04-12 FR FR1559541D patent/FR1559541A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT281064B (de) | 1970-05-11 |
| US3527758A (en) | 1970-09-08 |
| NL6804247A (enExample) | 1968-10-14 |
| CH512497A (de) | 1971-09-15 |
| GB1185408A (en) | 1970-03-25 |
| IE32004B1 (en) | 1973-03-07 |
| IL29735A0 (en) | 1968-06-20 |
| IE32004L (en) | 1968-10-13 |
| FR1559541A (enExample) | 1969-03-07 |
| SE354865B (enExample) | 1973-03-26 |
| DE1770174A1 (de) | 1971-09-23 |
| BE713471A (enExample) | 1968-10-10 |
| IL29735A (en) | 1971-08-25 |
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