ES349847A1 - Procedimiento para la preparacion de nuevos 1-fenoxi-2hi- droxi-3-alcohilamonopropanos sustituidos, racemicos u opti- camente activos. - Google Patents
Procedimiento para la preparacion de nuevos 1-fenoxi-2hi- droxi-3-alcohilamonopropanos sustituidos, racemicos u opti- camente activos.Info
- Publication number
- ES349847A1 ES349847A1 ES349847A ES349847A ES349847A1 ES 349847 A1 ES349847 A1 ES 349847A1 ES 349847 A ES349847 A ES 349847A ES 349847 A ES349847 A ES 349847A ES 349847 A1 ES349847 A1 ES 349847A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- racemic
- preparation
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 230000003301 hydrolyzing effect Effects 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- GGMMAAJZMHANAP-UHFFFAOYSA-N C(C(=O)O)(=O)O.COC(=O)C1=CC=C(OCC(CNC(C)C)OC2OCCCC2)C=C1 Chemical compound C(C(=O)O)(=O)O.COC(=O)C1=CC=C(OCC(CNC(C)C)OC2OCCCC2)C=C1 GGMMAAJZMHANAP-UHFFFAOYSA-N 0.000 abstract 1
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000000466 oxiranyl group Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0091070 | 1967-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES349847A1 true ES349847A1 (es) | 1970-04-16 |
Family
ID=6985633
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES349847A Expired ES349847A1 (es) | 1967-02-06 | 1968-01-27 | Procedimiento para la preparacion de nuevos 1-fenoxi-2hi- droxi-3-alcohilamonopropanos sustituidos, racemicos u opti- camente activos. |
| ES369537A Expired ES369537A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2 - hidroxi-3-alhocilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369538A Expired ES369538A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3 - alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES69369543A Expired ES369543A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369539A Expired ES369539A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369542A Expired ES369542A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi - 2 - hidroxi - 3 - alcohilaminopropanos sustituidos, racemicos u opticamente activos. |
| ES369541A Expired ES369541A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369540A Expired ES369540A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-alcohilaminopropanos sustituidos, racericos u op- ticamente activos. |
| ES69369544A Expired ES369544A1 (es) | 1967-02-06 | 1969-07-15 | Un procedimiento para la preparacion de nuevos 1-fenixi-2- hidroxi-3- alcohilaminopropanos sustituidos, racemicos u op-ticamente activos. |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES369537A Expired ES369537A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2 - hidroxi-3-alhocilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369538A Expired ES369538A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3 - alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES69369543A Expired ES369543A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369539A Expired ES369539A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369542A Expired ES369542A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi - 2 - hidroxi - 3 - alcohilaminopropanos sustituidos, racemicos u opticamente activos. |
| ES369541A Expired ES369541A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos sustituidos, racemicos u op- ticamente activos. |
| ES369540A Expired ES369540A1 (es) | 1967-02-06 | 1969-07-15 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-alcohilaminopropanos sustituidos, racericos u op- ticamente activos. |
| ES69369544A Expired ES369544A1 (es) | 1967-02-06 | 1969-07-15 | Un procedimiento para la preparacion de nuevos 1-fenixi-2- hidroxi-3- alcohilaminopropanos sustituidos, racemicos u op-ticamente activos. |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE710400A (en。) |
| BG (2) | BG15030A3 (en。) |
| CH (10) | CH521310A (en。) |
| DE (1) | DE1593762A1 (en。) |
| ES (9) | ES349847A1 (en。) |
| FI (1) | FI49496C (en。) |
| FR (2) | FR1566349A (en。) |
| GB (1) | GB1227480A (en。) |
| IE (1) | IE32353B1 (en。) |
| IL (1) | IL29416A (en。) |
| NL (2) | NL139236B (en。) |
| SE (1) | SE359292B (en。) |
| YU (4) | YU32762B (en。) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA945172A (en) * | 1969-02-21 | 1974-04-09 | Imperial Chemical Industries Limited | Alkanolamine derivatives |
| JPS4875539A (en。) * | 1972-01-12 | 1973-10-11 | ||
| JPS49245A (en。) * | 1972-04-17 | 1974-01-05 | ||
| DE2839475A1 (de) * | 1978-09-11 | 1980-03-20 | Dolorgiet Arzneimittelfabrik | Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
| US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| DE3407695A1 (de) * | 1984-03-02 | 1985-09-12 | Röhm Pharma GmbH, 6108 Weiterstadt | Pteridinverbindungen mit pharmazeutischer wirksamkeit |
| US4665094A (en) * | 1985-08-29 | 1987-05-12 | Merck & Co., Inc. | Oculoselective beta-blockers for treatment of elevated intraocular pressure |
-
1967
- 1967-02-06 DE DE19671593762 patent/DE1593762A1/de active Pending
-
1968
- 1968-01-27 ES ES349847A patent/ES349847A1/es not_active Expired
- 1968-02-01 CH CH1374270A patent/CH521310A/de not_active IP Right Cessation
- 1968-02-01 CH CH1373970A patent/CH510633A/de not_active IP Right Cessation
- 1968-02-01 CH CH1374570A patent/CH510637A/de not_active IP Right Cessation
- 1968-02-01 CH CH1374370A patent/CH511212A/de not_active IP Right Cessation
- 1968-02-01 CH CH1373770A patent/CH510631A/de not_active IP Right Cessation
- 1968-02-01 CH CH1374070A patent/CH510634A/de not_active IP Right Cessation
- 1968-02-01 CH CH153968A patent/CH506482A/de not_active IP Right Cessation
- 1968-02-01 CH CH1374170A patent/CH510635A/de not_active IP Right Cessation
- 1968-02-01 CH CH1374470A patent/CH510636A/de not_active IP Right Cessation
- 1968-02-01 CH CH1373870A patent/CH510632A/de not_active IP Right Cessation
- 1968-02-05 IL IL6829416A patent/IL29416A/xx unknown
- 1968-02-05 YU YU0252/68*7A patent/YU32762B/xx unknown
- 1968-02-06 FR FR1566349D patent/FR1566349A/fr not_active Expired
- 1968-02-06 BG BG011429A patent/BG15030A3/bg unknown
- 1968-02-06 SE SE01539/68A patent/SE359292B/xx unknown
- 1968-02-06 IE IE152/68A patent/IE32353B1/xx unknown
- 1968-02-06 FI FI680290A patent/FI49496C/fi active
- 1968-02-06 BG BG011427A patent/BG15028A3/bg unknown
- 1968-02-06 FR FR138848A patent/FR8040M/fr not_active Expired
- 1968-02-06 NL NL686801661A patent/NL139236B/xx unknown
- 1968-02-06 BE BE710400D patent/BE710400A/xx unknown
- 1968-02-06 GB GB1227480D patent/GB1227480A/en not_active Expired
-
1969
- 1969-07-15 ES ES369537A patent/ES369537A1/es not_active Expired
- 1969-07-15 ES ES369538A patent/ES369538A1/es not_active Expired
- 1969-07-15 ES ES69369543A patent/ES369543A1/es not_active Expired
- 1969-07-15 ES ES369539A patent/ES369539A1/es not_active Expired
- 1969-07-15 ES ES369542A patent/ES369542A1/es not_active Expired
- 1969-07-15 ES ES369541A patent/ES369541A1/es not_active Expired
- 1969-07-15 ES ES369540A patent/ES369540A1/es not_active Expired
- 1969-07-15 ES ES69369544A patent/ES369544A1/es not_active Expired
-
1973
- 1973-02-08 NL NL7301803A patent/NL7301803A/xx unknown
- 1973-06-05 YU YU1498/73A patent/YU32763B/xx unknown
- 1973-06-05 YU YU1493/73A patent/YU32761B/xx unknown
- 1973-06-05 YU YU01494/73A patent/YU149473A/xx unknown
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