ES341322A1 - Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. - Google Patents

Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas.

Info

Publication number
ES341322A1
ES341322A1 ES341322A ES341322A ES341322A1 ES 341322 A1 ES341322 A1 ES 341322A1 ES 341322 A ES341322 A ES 341322A ES 341322 A ES341322 A ES 341322A ES 341322 A1 ES341322 A1 ES 341322A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
phenyl
pyrazinamido
pyrazinoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES341322A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES341322A1 publication Critical patent/ES341322A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES341322A 1966-08-25 1967-06-02 Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. Expired ES341322A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57491066A 1966-08-25 1966-08-25

Publications (1)

Publication Number Publication Date
ES341322A1 true ES341322A1 (es) 1968-10-01

Family

ID=24298148

Family Applications (1)

Application Number Title Priority Date Filing Date
ES341322A Expired ES341322A1 (es) 1966-08-25 1967-06-02 Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas.

Country Status (6)

Country Link
BE (1) BE699436A (ru)
CH (1) CH487167A (ru)
DK (1) DK115846B (ru)
ES (1) ES341322A1 (ru)
GB (1) GB1158399A (ru)
NL (1) NL6707564A (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246406A (en) * 1979-03-27 1981-01-20 Merck & Co., Inc. Heterocyclic substituted pyrazinoylguanidines
US4224447A (en) * 1979-03-27 1980-09-23 Merck & Co., Inc. Novel pyrazinecarboxamides and processes for preparing same
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
KR101578235B1 (ko) 2007-12-10 2015-12-16 노파르티스 아게 유기 화합물
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
PT2931713T (pt) 2012-12-17 2017-02-22 Parion Sciences Inc Derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por insuficiente hidratação das mucosas
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
CH487167A (de) 1970-03-15
NL6707564A (ru) 1968-02-26
DK115846B (da) 1969-11-17
BE699436A (ru) 1967-12-04
GB1158399A (en) 1969-07-16

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