ES337729A2 - Derivatives of Ergolene - Google Patents

Derivatives of Ergolene

Info

Publication number
ES337729A2
ES337729A2 ES337729A ES337729A ES337729A2 ES 337729 A2 ES337729 A2 ES 337729A2 ES 337729 A ES337729 A ES 337729A ES 337729 A ES337729 A ES 337729A ES 337729 A2 ES337729 A2 ES 337729A2
Authority
ES
Spain
Prior art keywords
ergolene
prepared
treatment
acid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES337729A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH345566A external-priority patent/CH482831A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES337729A2 publication Critical patent/ES337729A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/183—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing an indolo[4,3-F,G]quinoleine nucleus, e.g. compound containing the lysergic acid nucleus as well as the dimeric ergot nucleus

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

6-Methyl-#8'9-ergolene-8-carboxylic acid is prepared by cultivating a mutant of the strain of Claviceps paspali Stevens et Hall NRRL 3080, prepared by irradiation with ultraviolet rays and/or X-rays and/or treatment with ethylene imine, in a nutrient medium and isolating the acid therefrom. Lysergic and isolysergic acid are obtained by isomerizing the above compound by treatment with a base followed by acidification.
ES337729A 1966-03-10 1967-03-08 Derivatives of Ergolene Expired ES337729A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH345566A CH482831A (en) 1963-08-29 1966-03-10 Process for the production of lysergic acid derivatives

Publications (1)

Publication Number Publication Date
ES337729A2 true ES337729A2 (en) 1968-08-16

Family

ID=4256304

Family Applications (1)

Application Number Title Priority Date Filing Date
ES337729A Expired ES337729A2 (en) 1966-03-10 1967-03-08 Derivatives of Ergolene

Country Status (7)

Country Link
AT (1) AT285063B (en)
BE (1) BE695214A (en)
DE (1) DE1642745C3 (en)
DK (1) DK118231B (en)
ES (1) ES337729A2 (en)
GB (1) GB1181836A (en)
NL (1) NL6703461A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795728B1 (en) * 1999-07-02 2001-09-07 Aventis Pharma Sa PROCESS FOR THE PREPARATION OF LYSERGIC ACID

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1140676B (en) * 1960-06-09 1962-12-06 Schloemann Ag Printing or injection molding machine with hydraulic locking device for locking the closing part in the mold closing position
GB1067513A (en) * 1963-08-29 1967-05-03 Sandoz Ltd Derivatives of ergolene

Also Published As

Publication number Publication date
DK118231B (en) 1970-07-27
DE1642745C3 (en) 1981-11-26
BE695214A (en) 1967-09-08
DE1642745A1 (en) 1971-05-19
GB1181836A (en) 1970-02-18
NL6703461A (en) 1967-09-11
AT285063B (en) 1970-10-12
DE1642745B2 (en) 1981-04-02

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