ES331789A1 - Procedimiento para la preparacion de derivados del 2-anilino-1,3-diazaciclopenteno-(2) con accion sedante y depresora de la presion sanguinea. - Google Patents
Procedimiento para la preparacion de derivados del 2-anilino-1,3-diazaciclopenteno-(2) con accion sedante y depresora de la presion sanguinea.Info
- Publication number
- ES331789A1 ES331789A1 ES0331789A ES331789A ES331789A1 ES 331789 A1 ES331789 A1 ES 331789A1 ES 0331789 A ES0331789 A ES 0331789A ES 331789 A ES331789 A ES 331789A ES 331789 A1 ES331789 A1 ES 331789A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- methyl
- reacted
- see formula
- see
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000036772 blood pressure Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000001624 sedative effect Effects 0.000 title abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 239000000460 chlorine Substances 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical class NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- YZKMURMKJCXVIE-UHFFFAOYSA-N 1-(2-aminoethyl)-3-phenylurea Chemical compound NCCNC(=O)NC1=CC=CC=C1 YZKMURMKJCXVIE-UHFFFAOYSA-N 0.000 abstract 1
- PQXUSNYJJTUETQ-UHFFFAOYSA-N 1-nitro-1-phenylguanidine Chemical class NC(=N)N([N+]([O-])=O)C1=CC=CC=C1 PQXUSNYJJTUETQ-UHFFFAOYSA-N 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkyl mercaptoimidazoline Chemical compound 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0083964 | 1965-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES331789A1 true ES331789A1 (es) | 1967-11-01 |
Family
ID=6982208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0331789A Expired ES331789A1 (es) | 1965-10-01 | 1966-09-30 | Procedimiento para la preparacion de derivados del 2-anilino-1,3-diazaciclopenteno-(2) con accion sedante y depresora de la presion sanguinea. |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE687656A (es) |
| CH (1) | CH484912A (es) |
| CS (2) | CS155146B2 (es) |
| DK (1) | DK115627B (es) |
| ES (1) | ES331789A1 (es) |
| FI (1) | FI46959C (es) |
| FR (2) | FR6998M (es) |
| GB (1) | GB1141487A (es) |
| IL (1) | IL26613A (es) |
| IT (1) | IT7949465A0 (es) |
| NL (3) | NL156398B (es) |
| PL (1) | PL79137B1 (es) |
| SE (1) | SE331280B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE755270A (fr) * | 1969-08-27 | 1971-02-25 | Sandoz Sa | Nouveaux derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives |
| DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
| DE2854659A1 (de) * | 1978-12-18 | 1980-07-10 | Boehringer Sohn Ingelheim | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| HU192986B (en) | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
-
1966
- 1966-09-30 DK DK506966AA patent/DK115627B/da unknown
- 1966-09-30 ES ES0331789A patent/ES331789A1/es not_active Expired
- 1966-09-30 NL NL6613829.A patent/NL156398B/xx not_active IP Right Cessation
- 1966-09-30 SE SE13242/66A patent/SE331280B/xx unknown
- 1966-09-30 FR FR78361A patent/FR6998M/fr not_active Expired
- 1966-09-30 BE BE687656D patent/BE687656A/xx not_active IP Right Cessation
- 1966-09-30 FR FR78365A patent/FR1506407A/fr not_active Expired
- 1966-09-30 CH CH1414166A patent/CH484912A/de not_active IP Right Cessation
- 1966-10-01 PL PL1966116712A patent/PL79137B1/pl unknown
- 1966-10-01 CS CS486672*1A patent/CS155146B2/cs unknown
- 1966-10-01 CS CS629466A patent/CS155145B2/cs unknown
- 1966-10-01 FI FI662577A patent/FI46959C/fi active
- 1966-10-02 IL IL26613A patent/IL26613A/en unknown
- 1966-10-03 GB GB44068/66A patent/GB1141487A/en not_active Expired
-
1977
- 1977-09-14 NL NL7710061A patent/NL7710061A/xx not_active Application Discontinuation
- 1977-09-14 NL NL7710062A patent/NL7710062A/xx not_active Application Discontinuation
-
1979
- 1979-06-19 IT IT7949465A patent/IT7949465A0/it unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE687656A (es) | 1967-03-30 |
| NL156398B (nl) | 1978-04-17 |
| IT7949465A0 (it) | 1979-06-19 |
| SE331280B (es) | 1970-12-21 |
| PL79137B1 (en) | 1975-06-30 |
| DK115627B (da) | 1969-10-27 |
| GB1141487A (en) | 1969-01-29 |
| CS155146B2 (es) | 1974-05-30 |
| NL7710062A (nl) | 1978-01-31 |
| NL6613829A (es) | 1967-04-03 |
| CH484912A (de) | 1970-01-31 |
| FR1506407A (fr) | 1967-12-22 |
| CS155145B2 (es) | 1974-05-30 |
| FI46959B (es) | 1973-05-02 |
| FR6998M (es) | 1969-06-02 |
| IL26613A (en) | 1970-07-19 |
| FI46959C (fi) | 1973-08-10 |
| NL7710061A (nl) | 1978-01-31 |
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